|
HS Code |
465431 |
| Iupac Name | 4-Amino-2,6-di-tert-butylphenol |
| Cas Number | 88-60-8 |
| Molecular Formula | C14H23NO |
| Molecular Weight | 221.34 g/mol |
| Appearance | Off-white to light yellow crystalline powder |
| Melting Point | 166-170 °C |
| Solubility In Water | Insoluble |
| Density | 1.06 g/cm³ |
| Flash Point | 155 °C |
| Synonyms | 4-Amino-2,6-di-tert-butylphenol; 2,6-Di-tert-butyl-4-aminophenol |
| Pubchem Cid | 6947 |
As an accredited Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl)- is packaged in a 100-gram amber glass bottle with a tamper-evident screw cap. |
| Shipping | Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl)- should be shipped in tightly sealed, chemical-resistant containers, clearly labeled, and protected from light and moisture. It must comply with relevant hazardous material transport regulations (such as DOT, IATA, or IMDG), ensuring appropriate documentation, safety data sheets (SDS), and secondary containment to prevent leakage during transit. |
| Storage | Store Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl)- in a tightly closed container, in a cool, dry, well-ventilated area, away from incompatible substances such as strong oxidizing agents and acids. Protect from light and moisture. Use appropriate secondary containment, and ensure storage area is equipped with spill control and proper hazard identification. Avoid contact and inhalation; only handle using suitable protective equipment. |
Competitive Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl)- prices that fit your budget—flexible terms and customized quotes for every order.
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At our production site, Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl) stands out as one of the specialty chemicals that ties decades of experience with current industry needs. Every batch reflects our focus on purity, repeatability, and a thorough grasp of how this compound behaves under different conditions. Recognized in the lab as 4-Amino-2,6-di-tert-butylphenol, our process brings out its distinguishing qualities, putting to use what we have learned from countless synthesis runs and client feedback sessions.
This compound attracts attention due to its bulky tert-butyl groups at the 2 and 6 positions, which aren’t just a twist on simpler phenols—they significantly reshape its reactivity profile, shelf stability, handling, and downstream uses. While others might seek a basic phenolic antioxidant or an aromatic amine, many industries require something more tailored. Our experience tells us that this molecule’s unique mix of functional groups gives formulators a broader palette, both in terms of chemical compatibility and physical performance.
Our batches of 4-Amino-2,6-di-tert-butylphenol follow strict specification limits, reflecting years of adjustments to synthesis and purification. Most of our customers need a compound with high assay (above 99 percent), limited moisture content, and defined melting point. We manage these targets through precise temperature gradients, controlled addition rates, and frequent in-process sampling. The incoming raw materials go through a double-check process; without it, out-of-specification lots could push up purification costs or create handling headaches later.
The white to pale yellow crystalline appearance acts as a visual first check: discoloration hints at trace oxidation or polymerization. We only release lots when the HPLC purity surpasses 99 percent and the melting range falls between 151 to 153 °C—benchmarks selected after years working side-by-side with research and technical staff facing the realities of downstream reactions, resin modification or polymer compounding. Water, as so many in this field know, causes trouble both in reactions and through caking, so we dry under vacuum and pack with desiccants immediately after final isolation.
We hear from coatings chemists, lubricant formulators, and antioxidant developers that batch-to-batch consistency is a deal breaker. Our technical staff participate directly in process troubleshooting and lab-scale application studies. When a batch risked higher by-product formation due to a subtle temperature swing, they were the first to spot it and adjust our reflux parameters. Small details like this make a compound reliable beyond analytical purity charts—they determine how products perform once they leave our facility and get blended or reacted by our clients’ chemists.
Over time, the uses for 4-Amino-2,6-di-tert-butylphenol have expanded from niche stabilizer roles to diverse application areas. This material first proved itself as an oxidation inhibitor in greases and lubricants, especially under thermal stress. The tert-butyl groups protect the phenolic core, lowering volatility and improving resistance to degradation during high-temperature operation—a recurring issue with simpler phenols and amines. Lubricant formulators using this product have reported slower color change and reduced sludge formation in extended engine testing. That isn’t just marketing talk; we have received returned lubricant samples where our chemists confirmed oxidative stability benefits through chromatographic analysis.
In polymer modification, this compound wins out for its fusion of antioxidant and amine functionality. The amino group allows for possible further derivatization—linking onto resins, building blocks for curing agents, and even certain pharmaceutical intermediates where sterics and electron donation matter. In polyurethane R&D, for example, we supplied this molecule to partners exploring novel chain extenders. They noted improved hydrolytic resistance and lighter final color compared to alternatives lacking the extra tert-butyl shielding effect.
For epoxy resin systems, the story shifts slightly. Our direct conversations with end-users uncovered that simple phenols tended to suffer from yellowing, especially on prolonged UV exposure or post-cure heat treatment. This amino-tert-butyl derivative, with its greater radical trapping ability and steric hindrance, slows that yellowing and offers end-products greater visual clarity and longer lifespan. Several adhesive and encapsulant formulators have substituted older, more volatile antioxidants with our product—including in electronics and transportation sectors—after head-to-head trials demonstrated better performance and cleaner end-process spectra.
Some clients explore this amino phenol in dye chemistry, though the structure limits some coupling reactions due to steric effects. Where the synthesis method demands strong electron donation without excessive side reactivity, our batches perform well, enabling sharper color shades in final dye lots and reduced by-product formation. These are nuanced advantages, understood only after being involved in mill-scale and pilot-lot syntheses, fielding questions, and troubleshooting mid-reaction surprises alongside technical leads at client facilities.
Many in the chemical business know phenolic stabilizers are a crowded field. Simple phenols lack the steric protection provided by tert-butyl groups, making them more prone to air oxidation. Products with only amine function tend to react readily but can also degrade faster or form colored by-products under stress. The dual protection in 4-Amino-2,6-di-tert-butylphenol shields both the phenol ring and the amino group, reducing volatility, increasing shelf stability, and cutting risk of color changes during processing.
Analogues with mono-tert-butyl substitution or without amino groups show lower threshold resistance to thermal oxidative stress. We’ve run comparative testing in grease aging and polymer extruder trials, monitoring acid value, color, and residual active content after extended cycling. Simple phenol stabilizers drop off in performance at elevated heat and oxygen concentrations. Our product keeps its mass and function longer, thanks to both chemical shielding and molecular bulk. This isn’t a theoretical benefit: we supply directly to polymer compounders and synthetic lubricant refiners who provide us with accelerated stress test results. Our batch testing aligns with their field data, closing the loop and spurring further modest improvements each year.
Some producers offer closely related molecules with different positional isomers or fewer tert-butyl groups. These alternatives cost less to synthesize, but customers dealing with exacting color or thermal demands see the difference, especially in long-duration stress environments. The evidence comes from side-by-side sample trials we conducted alongside procurement and lab teams in Europe and Asia—their feedback and returned product histories provide plenty of data points. No amount of generic datasheet comparison replaces receiving real-world feedback after three or six months in a finished product.
For some end uses, volatility and compatibility with reactive diluents or polymer matrices is key. Our product, with its higher molecular weight and reduced vapor pressure, leads to less evaporation loss in hot processing conditions. This has direct impact: less loss during extrusion, reduced migration in high-temperature service, and lower tendency to alter mechanical properties in cured systems.
Producing a compound like 4-Amino-2,6-di-tert-butylphenol brings home the importance of close supply chain monitoring and hands-on technical support. We source key raw materials from vetted upstream partners and audit their facilities in person. In periods of upstream volatility—like during supply interruptions caused by regulatory changes or logistics disruptions—we keep buffer stocks and run parallel syntheses to avoid letting impurities accumulate or disrupting downstream deliveries. The learning curve on this product included a few tough seasons: temperature swings, raw material shortages, and labor constraints, but the operational lessons strengthened our process control systems and staff training.
Clients often share concerns regarding exact active content or residual impurities due to the impact on process safety and finished product certifications. Regulatory awareness plays a role: certain applications in food packaging, sensitive adhesives, or critical automotive materials require extremely low impurity thresholds and detailed batch histories. Our site keeps full lot traceability and stores samples for post-market analysis. This matters most in projects where a small contamination or a run of low-purity material could halt production or force customer recalls.
The importance of communication flows both ways. We run technical workshops with downstream users and incorporate feedback on melting behavior, solution color, and filtration ease. This gives us a working understanding of day-to-day realities on client production lines, labs, and warehouses. Once, a customer reported increased filter clogging in their polymer compounding; quick coordination between our R&D and their plant staff traced the issue to a subtle shift in crystallization protocol. We tweaked the cooling profile: filter performance recovered, and that mutual problem-solving spirit continues. It’s easy to discuss quality in abstract terms. It’s much harder, but more rewarding, to stay honest with partners about what works and what needs improvement.
As global regulations tighten, especially on low-toxicity and low-volatility ingredients, we see shifting client preferences. Recent years brought questions about residual metals, unreacted starting materials, and by-products. Early in our production experience, we tested several catalyst systems, but only after fielding questions from partners in high-purity elastomer and electronics production did we redesign our protocol to reduce trace metals. We’ve implemented extra steps in washing and solid-phase purification, not just to meet regulatory reporting but to keep up with evolving performance demands. The effort pays off through lower rates of batch rejection and a reputation for dependable, problem-solving technical support.
Sustainability also finds its way into every planning meeting. We view reusing solvents, minimizing solvent emissions, and recycling minor by-products as priorities, not just paperwork obligations. Energy efficiency enters into day-to-day thinking: temperature ramps are optimized, and waste heat is recovered from synthesis steps. We switched to lower-impact packaging years ago, after customers pointed out difficulties in waste disposal for drums lined with film. These initiatives grow out of real, on-the-floor experience—small steps that add up to both less environmental impact and stronger relationships.
Another market trend we track is the need for multi-functional stabilizers. As automotive, electronics, and high-performance coatings industries converge around higher durability, the need for active compounds that pull double duty (antioxidant and amine function, for example) increases. Our experience supplying both pilot trials and full-scale launches taught us that users don’t just buy a chemical; they invest in reliable supply, technical familiarity, and honest answers—qualities that only come from years of engagement with the product, the process, and the people on both sides of the supply chain.
Technical datasheets matter, but we find they rarely get to the root of why a specialty chemical actually solves a problem on the plant floor or in the field. Hands-on trials, collaborative troubleshooting, and a willingness to adapt production protocols together with partners counts for more. We visit client facilities, run applications support, and roll findings back into our own process improvement cycles.
Looking back, confidence in our product grew not from abstract metrics but from the actual use and adaptation by diverse customers. Some of our longest relationships started from a returned sample or an offhand suggestion during an onsite product line audit. The technical back-and-forth, the sharing of batch performance data, and the occasional tough conversation have built trust—and that translates into repeat supply and a deeper sense of partnership.
On the production line, stability isn’t just a theoretical benefit—it saves rework, cuts maintenance, and avoids expensive downtime for our clients. Our production operators and chemistry staff see the link between good process discipline and solid, shelf-stable product. One overlooked point: surface morphology. Our improvement of crystal habit (from early batches with irregular, jagged grains to today’s flow-friendly powder) stemmed from repeated client feedback about automated feeding and mixing. These hands-on improvements enhanced flow, ease of dispersion, and consistency in large scale blending.
Moisture control required its own round of learning. A decade ago, losing one drum to caking after hot weather taught us to double-seal packing containers and rotate storage more closely. Now, tracking humidity, quick turnaround between final drying and packing, and real-time monitoring means we rarely hear complaints of lumps or slow dispersion. In cold and hot climates—from user reports in both South Asia and North America—storage performance holds up, and nobody wants to spend extra hours breaking up clumped material.
What sets Phenol, 4-Amino-2,6-Bis(1,1-Dimethylethyl) apart in our shop isn’t just its reactivity or robustness, but the accumulated experience shaping its production. Every time our technical staff engage with customers, from troubleshooting off-odors in a resin batch to advising on antioxidant dosage rates for grease manufacturers, those lessons feed back into continuous improvement. Meeting rising chemical and regulatory standards isn’t a chore—it comes from staying close to the field, tracing not just what goes right but what stumbles, and taking pride in every lot that meets the strictest user standards.
We believe that a specialty chemical earns its value where supply expertise and technical experience merge. The relationships with our partners—built on responsiveness, technical transparency, and the everyday craft of making, testing, and improving—make the difference. Decades of production, learning, and mutual trust inform every drum and every consultation, supporting both practical performance and the enduring success of those who depend on this reliable, distinctive phenolic amine.