|
HS Code |
477668 |
| Iupac Name | 3-(Methylamino)phenol |
| Molecular Formula | C7H9NO |
| Molar Mass | 123.15 g/mol |
| Cas Number | 17628-44-9 |
| Appearance | White to off-white solid |
| Melting Point | 66-70 °C |
| Boiling Point | 263-264 °C |
| Density | 1.15 g/cm³ (approximate) |
| Solubility In Water | Soluble |
| Pka | 9.7 (phenol OH group) |
| Synonyms | m-(Methylamino)phenol, 3-Hydroxy-N-methylaniline |
| Smiles | CCNC1=CC(=CC=C1)O |
| Inchi | InChI=1S/C7H9NO/c1-8-6-3-2-4-7(9)5-6/h2-5,8-9H,1H3 |
| Pubchem Cid | 1551337 |
| Hazard Statements | Irritant to skin, eyes, and respiratory tract |
As an accredited Phenol, 3-(Methylamino)- factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 100-gram amber glass bottle with a tight-sealed cap, labeled “Phenol, 3-(Methylamino)-” and detailed safety information. |
| Shipping | Phenol, 3-(Methylamino)- should be shipped in accordance with hazardous materials regulations. It must be packed in secure, leak-proof containers and labeled with appropriate hazard warnings. Transport should be by authorized carriers, avoiding extreme temperatures. Proper documentation and emergency response information must accompany the shipment to ensure safe handling and compliance. |
| Storage | **3-(Methylamino)phenol** should be stored in a cool, dry, and well-ventilated area, away from incompatible substances such as oxidizers and acids. Keep the container tightly closed, protected from light and moisture. Store in a labeled, chemical-resistant container, and avoid exposure to heat or open flame. Ensure appropriate safety measures and access to spill control equipment in the storage area. |
Competitive Phenol, 3-(Methylamino)- prices that fit your budget—flexible terms and customized quotes for every order.
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Years on the manufacturing floor teach something no textbook offers: attention to the finer details builds reliability into every drum, vial, or tanker that leaves the gate. In the world of chemical production, trust grows batch by batch. Phenol, 3-(Methylamino)- reflects this mentality from start to finish. Over the past decades, we have watched industry needs become sharper and compliance bars rise higher, and our team has used that pressure to refine what we deliver. This compound has grown into a mainstay across synthesis labs and industrial facilities seeking a phenolic derivative with a single methylamino group in the meta position. What truly matters to users is not only the baseline level of purity and identity, but also confidence that every shipment behaves the same way the last did—whether it’s stored for weeks or weighs out for use the moment it arrives.
In the day-to-day of chemical manufacturing, variations in raw material or small shifts in temperature can throw an entire process out of alignment. 3-(Methylamino)-phenol, often referred to by its CAS number or its function in downstream reactions, occupies a rather specific spot. Its chemical structure—phenol substituted at the meta position by a methylamino group—provides a unique balance of reactivity and stability. Labs particularly value the ease with which it participates in further derivatization. Manufacturers in dye intermediates, photographic chemicals, and specialty polymers notice that. Our regular feedback from long-term clients shows this: users return for consistency, not marketing gloss.
Mistakes during isolation or discrepancies in solvent removal show up later as problems in the customer’s process. That has pushed us to refine every stage: raw material audits, closed-system reactors, fraction-by-fraction QA testing, and freshly sealed drums just hours before shipping. Our process aims to catch the impurities catalogued in the literature and those that slip through the usual checks—complex amines, high-boiling phenolics, tars that diminish reactivity, and anything not supposed to be there. This focus comes from hard-won lessons: surprises in high-value, low-volume batches almost never favor either the supplier or the end user.
Feedback keeps our baseline higher than any datasheet. Over time, we revised the melting and boiling point specifications, knowing slight shifts there can mark batch-to-batch changes unnoticed elsewhere. The color, odor, and crystallinity of 3-(Methylamino)-phenol tell skilled eyes if the batch will play nicely in complex formulations. End users in dye manufacturing mention minute changes in color development when using inferior lots. Hearing back from those formulating antioxidant packages, specialty paints, or developing new high-performance resins, we learned how a stray fraction of an impurity can pull an entire system off spec. That’s why our quality team puts its energy not just into measuring routine parameters, but learning how the product interacts in end uses you can’t always predict up front.
Warehousing, packing, and transport add new layers of challenge. Customers once explained a shipment had faint off-odors after overseas transit in hotter weather—a sign of less-than-optimal sealing or minor reaction flux. We went back to packing and changed liners, updated fill protocols, and tracked drum atmospheres all the way to the destination. Each action shapes the product that customers eventually use. This direct feedback loop means you don’t receive a product that’s only lab-grade when it departs but at every stage on its journey.
Talk with five users and you’ll hear five stories: one laboratory might highlight its role as a precursor for azo dye synthesis, focusing on the compound’s amine function and how its position enhances color-fastness or suitability for certain substrates. An R&D specialist developing antioxidants points to the subtle electron-donating effects in the para and meta positions, crucial to oxidative stability in advanced lubricants. Photographic chemical manufacturers bring up reactivity profiles and stability in developer solutions. Then there are the polymer innovators, who count on both the phenolic behavior and amine reactivity to weave specialized structures with unique thermal and chemical resistance. Every industry’s process has its quirks, and each one will stress features like melting point accuracy, absence of colored byproducts, or minimal water content. Over years of listening to these priorities, we adjusted our specs, explored alternative filtration steps, or changed storage protocols to match feedback.
Something as simple as speed of dissolution in a specific solvent for one plant might become the pivotal point in a formulation bottleneck. That’s why we not only track the structural identity but also support with solubility and compatibility checks relevant to these nuanced industrial workflows. Sometimes our customers in pharmaceuticals or fine chemicals reach out with unique conversion processes, where they need the meta-methylamino substitution to provide a selectivity advantage in a particular synthetic route. These requests often push us to test additional attributes or offer pre-blended solutions tailored to a specific process window, strengthening how flexible we remain as a manufacturing partner.
Our history shapes how we view product quality and logistics. Handling the chemical from reaction flask to sealed drum puts every crucial variable under our control—choice of raw phenol, reagent purity, temperature curves during amination, even ambient humidity as crystals form. This matters to the final product’s performance. We have seen more than a few instances where products traded through multiple hands lose some form of identity—be it through packaging mishaps, unclear batch histories, or inconsistent labeling. Direct manufacturing lines create clear-cut documentation, precise batch records, and the ability to adjust any parameter as soon as a detail changes.
Regularly, we invite customer audits and joint testing. Partners interested in real traceability come see our reactors, sample from our intermediate vessels, and review the same analysis sheets we work with. Most who visit end up investing more trust in a face-to-face partnership versus an anonymous, cross-border trade that blurs the chain of custody. This shared accountability turns into faster root cause resolution, fewer surprise shortages, and long-term alignment to regulatory frameworks.
Demand for transparency and accountability keeps increasing. We see regulations everywhere pushing toward greener practices, solvent minimization, and more rigorous impurity tracking. In our own process, that has led to solvent recycling setups, closed-loop waste handling, and energy audits to cut resource use while increasing output stability. During supplier meetings, recurring questions come up: what auxiliary agents are used? What about metal contaminant traces? Can the process run without certain phthalates or traditional quenchers? Instead of leaving things to chance, we bring our process teams to the table, reviewing raw supplier audit trails, mapping historic impurity profiles, and running regular third-party analyses—all logged and ready to share with customers on demand.
In hazardous chemical management, safety isn’t just paperwork—it’s built into every routine. We start each shift with tool box meetings: levelheaded discussions on the lot currently running, expected deviations, and hands-on checks for contamination. This might seem excessive, but a minor misstep with 3-(Methylamino)-phenol stains downstream product, drives hazard ratings upwards, or triggers batch recalls. Our people know that compliance is measured not just by meeting regulatory minimums but by building a track record of zero surprises.
A focus on traceability goes beyond regulatory obligations. Customers sometimes seek complete "cradle-to-gate" histories, so information on each precursor lot, operator log, or batch flow record travels along with the shipment. Several industry groups now require proof of non-GMO, absence of certain animal-derived materials, or conflict-free sourcing. We took these shifts seriously; for 3-(Methylamino)-phenol, this means every part of the supply chain stands ready for audit.
Chemists understand that subtle structure changes transform chemical behavior. Simple phenol, as widely used as it is, brings reactivity but not always selectivity. Para-substituted methylamino phenols, ortho isomers, or even the unsubstituted homologs may show similar melting points or basic solubility but often differ markedly in reactivity profiles and side reaction rates. Feedback from our clients using para or ortho isomers in dye intermediates or as developers in photography often returns to one theme: side product profiles change, physical handling gets trickier, and downstream color development can veer off. The meta-position in 3-(Methylamino)-phenol borrows just enough from its electron-donating and withdrawing neighbors to be uniquely versatile—it’s that nuance which drives demand among process chemists optimizing for specificity or low-background reactivity.
In large-scale operations, isomeric purity grows in importance. Small double-digit percentages of off-isomer content cause cascading problems—off-shade dyes, unpredictable performance in high-performance adhesives, or uncontrolled byproduct islands in reaction vessels. We design our process to limit positional isomers as much as possible, going so far as running targeted GC and NMR verification beyond routine QA. Over the years, industry partners commented on reduced waste generation and more predictable scaling behavior when sourcing directly from our facility, thanks to this focus.
A key question we hear focuses on substitution patterns and how they impact toxicology or environmental persistence. Researchers in the environmental safety field indicate meta-substituted phenols generally display distinct breakdown rates and lower persistence under normal wastewater treatment compared to their para or ortho cousins. Our commitment to supporting environmental stewardship led us to co-sponsor studies with downstream users to better chart these differences and help guide responsible use and disposal options.
Direct manufacturer relationships unlock customization that simply doesn’t happen through trading houses. Over the years, we worked shoulder-to-shoulder with customers designing new developer systems for digital imaging, or developing antioxidant packages for next-generation transmission fluids. Quick iterations of purity tuning, form modification, or packaging adjustments lead to technical advances and, sometimes, patent wins for both our partners and our own R&D teams. In the last five-year stretch, a growing part of our business comes from co-developed materials, where we refine a base specification of 3-(Methylamino)-phenol to fit an emerging industrial need.
Technical support isn’t limited to clarifying a certificate of analysis. We regularly help customers troubleshoot processing issues, optimize dissolutions, or adapt handling procedures for automated dispensing—these changes lower batch cycle times or reduce in-house losses. Our technical teams make field visits, often at unusual hours, to help clients resolve real-time questions about stability or compatibility. Experience counts—customers wasting hours searching for off-the-shelf advice too often discover the problem comes from a nuance of manufacturing technique, not from a flaw in the lot itself.
Collaboration with academic partners adds another dimension. We maintain relationships with several university groups exploring new reaction pathways using 3-(Methylamino)-phenol as a scaffold for bioactive molecules. Direct feedback from bench chemists in those settings brings a reality check, bridging blue-sky ideas with day-to-day chemical manufacturing. This cycle of feedback and improvement lands in every update of our protocols and every improvement in the physical product that ships out.
Adaptability ensures survival. Global supply volatility in recent years highlighted the risks of single-source sourcing and long trade chains. We saw previously stable ports close and air freight networks reroute, prompting reviews of raw material reserves and just-in-time delivery strategies. Our response involved diversifying supply lines, expanding on-site material storage, and investing in more robust packaging systems. Clients benefit by knowing their critical inputs won’t get held up by logistics failures outside anyone’s control.
Research investments continue. Recent upgrades target energy efficiency in reactors, digitalization of process control, and automated impurity quantification—all making future production both environmentally lighter and more transparent. Up-to-date process analytics allow us to drop detection limits for residual solvents, color-forming side products, or heavy metals, sparing customers later remediation work. We anchor our technical training in these new tools—giving every process operator, warehouse worker, and lab chemist the knowledge they need to spot issues early and recommend improvements daily.
Energy-efficient processes and responsible chemical stewardship form part of every decision. Aging steam lines and outmoded reactors received upgrades. Solvent recovery reached levels we only dreamed about a decade ago. Investment in new dry rooms and staging areas keeps sensitive intermediates safe from unexpected temperature or humidity swings, as these fluctuations once cost us an entire production campaign. Such reinvestment speaks not to trend following, but to commitment—every dollar ploughed back into the plant returns in happier, more successful customers down the road.
Chemical production—especially of specialty intermediates like 3-(Methylamino)-phenol—demands more than basic compliance and shipping logistics. It benefits from direct lines of communication, hands-on quality management, and the willingness to constantly reevaluate practices in response to customer needs and regulatory changes. Over the years, working closely with R&D teams, plant operators, and sourcing managers, our commitment to producing reliable, high-purity phenolic amines hasn’t just supplied materials—it has fostered lasting value and innovation partnerships.
Our journey continues with every batch. We welcome in-depth conversations, application challenges, and site visits. Whether your business needs a stable supply for an established process or help developing a new downstream innovation, our doors remain open to collaboration and problem-solving, guided by real manufacturing know-how at every step.