|
HS Code |
793952 |
| Chemical Name | m-Acetophenol |
| Iupac Name | 3'-Hydroxyacetophenone |
| Cas Number | 121-71-1 |
| Molecular Formula | C8H8O2 |
| Molecular Weight | 136.15 g/mol |
| Appearance | White to off-white crystalline powder |
| Melting Point | 107-110 °C |
| Boiling Point | 280 °C |
| Density | 1.192 g/cm³ |
| Solubility In Water | Slightly soluble |
| Flash Point | 158 °C |
| Refractive Index | 1.548 |
| Pubchem Cid | 8138 |
| Smiles | CC(=O)C1=CC(=CC=C1)O |
| Ec Number | 204-491-6 |
As an accredited M-Acetophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle labeled “M-Acetophenol, 250g,” features hazard symbols, batch number, manufacturer details, and secure screw cap. |
| Shipping | M-Acetophenol should be shipped in tightly sealed containers, protected from light and moisture. It must be handled as a flammable solid, transported according to local and international regulations (UN/NA number applicable), with proper labeling and documentation. Avoid contact with incompatible materials, and ensure containers are upright and securely fastened during transit. |
| Storage | M-Acetophenol should be stored in a cool, dry, and well-ventilated area, away from incompatible materials such as strong oxidizers and acids. Keep the container tightly closed and protected from light. Store away from sources of ignition and heat. Use approved chemical storage containers and label them clearly. Implement appropriate spill containment and ensure access to safety equipment nearby. |
Competitive M-Acetophenol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615380400285 or mail to sales2@liwei-chem.com.
We will respond to you as soon as possible.
Tel: +8615380400285
Email: sales2@liwei-chem.com
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Years on the production floor have taught us that consistent quality and reliable supply aren’t buzzwords—they’re a daily necessity when it comes to chemicals like M-Acetophenol. We produce this compound in bulk because our customers rely on its stability, purity, and reactivity. What drives our work is the visible difference a well-made raw material can make across the chemical industry, whether in pharmaceuticals, fine chemicals, or dyes. Each batch of M-Acetophenol passes through a strict verification process grounded in years of feedback, troubleshooting, and process optimization.
M-Acetophenol stands out among related compounds for its structure: it’s a hydroxyacetophenone with the hydroxyl group in the meta position. This subtle structural detail changes everything. The meta arrangement delivers reactivity patterns distinct from para- or ortho- counterparts. With a molecular formula of C8H8O2 and molecular weight of 136.15 g/mol, it combines a moderate boiling point with good solubility in common solvents. Over time, we’ve learned that its selective reactivity makes it a staple in syntheses where para- or ortho-acetophenols would give undesirable by-products.
Our feedback loop involves more than listening to complaints; it’s about actively watching production performance from start to finish. M-Acetophenol typically arrives as pale-yellow to white crystals, thanks to our well-honed purification steps. The melting point, as measured batch after batch, lands reliably in the 108-110°C range. HPLC screenings verify purity consistently exceeds 99%. Water and residue levels stay minimal, as high-purity input raises the bar for downstream consistency and reduces filtration headaches. We’re not chasing arbitrary numbers; these metrics come from hard-won experience balancing process economy and chemical precision.
The chemical market often draws direct lines between meta-, para-, and ortho-acetophenols, but the distinctions become clear on the production line. With p-acetophenol, you get higher reactivity at the para position, which can complicate targeted syntheses. Ortho derivatives introduce steric hindrance, leading to lower yields when building more complex structures. M-Acetophenol simplifies post-reaction separation and cuts down on side-product formation, especially in multi-step pharmaceutical or dye production. Over the years, customers reported smoother yields with meta than with comparable grades of para, especially during large-scale coupling reactions.
Most people outside the lab see M-Acetophenol as a minor intermediate, but nearly every day we field questions about its pharmaceutical compatibility. Medicinal chemists appreciate M-Acetophenol for its predictable behavior in acylation and alkylation steps. Several downstream compounds, including numerous active pharmaceutical ingredients and intermediates, depend on the meta arrangement for their specific pharmacological profiles. Some of our long-term clients use M-Acetophenol in the synthesis of analgesics, antimicrobial agents, and even agricultural chemicals. None of this is an accident—years of feedback have shown that changing the acetophenol isomer shifts the safety, yield, and regulatory outcomes of the final product.
We’ve seen less experienced producers struggle with color formation, inconsistent melting points, and solvent contamination. Our process addresses these with redundant checks and in-process controls. For example, consistent fractional distillation under reduced pressure helps preserve the colorless state. We also maintain strict controls on raw material quality, since low-grade starting materials cause headaches downstream, especially in dye and pharmaceutical production. Multiple solvent rinses and re-crystallization cycles help eliminate off-odors and impurity bands. The final result is a crystalline product that saves our customers untold hours of rework and cleanup.
Rarely does a lab synthesis scale smoothly to full production. We’ve guided dozens of scale-ups for M-Acetophenol, and each one brought a new lesson. On paper, every production run should look alike, but variables—stirring speed, heating gradients, vessel material—suddenly transform a simple reaction into a challenge. We leverage continuous monitoring, from small pilot batches up to ton-scale reactors, to keep purity and yield optimal. Based on real-world experience, we maintain flexibility in production methods, like switching between batch and semi-continuous processes when raw material availability or customer timelines shift.
Our decades in this field have made environmental impact a personal concern. We’ve invested heavily in solvent recovery systems, lower-emission synthesis pathways, and energy efficiency upgrades throughout our M-Acetophenol production lines. Real progress shows up in lower emissions per kilogram of product and stricter wastewater recycling standards. Even seemingly small changes—like optimizing cooling water loops—add up on an industrial scale. Our environmental compliance team works side by side with production to hit evolving regulatory targets and maximize resource use. For our customers, this means supply that lines up with corporate sustainability reporting and passing environmental audits.
Global disruptions unsettle the fine chemicals market more often than anyone likes to admit. We respond by keeping raw material stockpiles, dual-source supply chains, and redundant reactor capacity. In dense production seasons, our team coordinates batch scheduling around customer deadlines to ensure uninterrupted supply. We keep a close eye on each order’s journey from reactor to warehouse, updating our partners in real time if something changes. We’ve built backup plans over years of direct experience with weather events, logistics bottlenecks, and shifts in demand. No one wants a shutdown due to a missing kilo of intermediate, and our record shows this is more than just sales talk.
M-Acetophenol’s profile appeals to innovation-minded chemists. New processes arrive every year, and our technical staff spends time walking customers through pilot reactions, process adaptations, and alternative solvent systems. Several customers in dye manufacturing have developed proprietary shades and fastness properties thanks to meta-acetophenol, and our team’s early input expedited their route to market. We don’t separate production from technical service because efficient troubleshooting happens at the intersection of supply knowledge and application expertise.
M-Acetophenol occasionally turns up as the weak link in a production chain, especially when customers source from unvetted suppliers. Batches that miss purity benchmarks introduce bottlenecks and cost overruns. Drawing from real situations, we support partners with historical COA data, retain samples for post-delivery investigations, and deploy technical staff for on-site troubleshooting when process problems trace back to our product. The open approach to handling complaints has earned us trust with repeat buyers and regulatory inspectors alike.
One graphics dye producer approached us after back-to-back line shutdowns. We audited their batch records and found the root cause: tiny impurity bands in the acetophenol input caused severe chromatic instability. On switching to our M-Acetophenol, they saw test batches pass color accuracy and lightfast standards for the first time in months. Our team then provided process notes to fine-tune their reaction temperature profile, cutting their QC hold times. This story isn’t unique—metal complex dyes, sulfur dyes, and even optical brighteners see real benefits from an input chemical that doesn’t create unexpected by-products.
Two years ago, a mid-sized pharmaceutical manufacturing operation contacted us during a vital scale-up. Their previous supplier’s meta-acetophenol kept triggering batch rejections due to unintended side reactions. Their chemists spent weeks tracing the issues, only to discover the analytical signature of by-product clusters common in unrefined product. Our in-house analytical chemist worked with their QA director to pinpoint possible culprits, and after transitioning to our material, rejection rates dropped by over 80%. Consistency in intermediates like M-Acetophenol ripples through the entire chain. Better input prevents costly troubleshooting and speeds up regulatory clearance.
In any plant, handling aromatic compounds involves careful trade-offs between safety, efficiency, and cost. We mandate enclosed transfer systems for dry goods and keep all staff trained in the correct use of PPE. M-Acetophenol carries the usual hazards of phenolic compounds: skin and eye irritation, mild volatility, and flashpoint considerations. We design packaging to simplify loading and reduce the risk of dust or spillage on site. Staff safety drills and real-life near-miss reporting cycles allowed us to design safer workflows and pass those lessons along to downstream users. These aren’t abstract protocols—they arise from watching and listening on the shop floor.
Process engineers and R&D chemists routinely ask about compatibility of M-Acetophenol with new solvents, increased reaction scales, and automation equipment. We encourage these questions, since every answer helps us improve both the product and the support behind it. With the meta-isomer, reaction profiles seldom shift unexpectedly between lab and production scales. That predictability lets engineers program batch control and automate purification, saving time and reducing error risk. For solvent compatibility, our continuous feedback loop surfaces new solvent blends that speed up product recovery, especially for customers moving toward greener process chemistry.
No batch of M-Acetophenol leaves our plant without a close look at both current standards and upcoming regulatory demands. Our team keeps pace with shifting expectations from global and regional agencies, so our partners don’t get caught flat-footed. The feedback from labs, production lines, and regulatory auditors feeds into our annual improvement cycles. We adjust our process flow, invest in new analytical tools, and sometimes rework an entire separation stage because a single customer’s insight made a difference in product performance. Continuous learning informs every kilogram produced.
We’ve witnessed first-hand the impact of poorly controlled raw materials on entire business lines. Unplanned plant shutdowns, unexpected side product peaks on HPLC, production schedule delays—each links back to minor lapses in upstream chemical quality or logistics. Reliable supply of M-Acetophenol transforms project risk into certainty. Customers depend on us for more than a product—they seek partnership, traceability, and a shared commitment to sustainable, high-quality chemical synthesis.
Over the years, our approach to manufacturing, quality control, and customer engagement set a benchmark for what a chemical producer should offer. We stand behind each shipment of M-Acetophenol not only because specifications say so, but because it holds up under the scrutiny of production lines, laboratory investigations, and loading docks worldwide. Our field knowledge, combined with our technical rigor, ensures customers receive not just a product, but a platform for continued success.
