|
HS Code |
168202 |
| Product Name | 5-Fluoro-2-Nitrophenol |
| Synonyms | 2-Nitro-5-Fluorophenol |
| Cas Number | 387-46-4 |
| Molecular Formula | C6H4FNO3 |
| Molecular Weight | 157.10 |
| Appearance | Yellow crystalline solid |
| Melting Point | 110-114°C |
| Solubility In Water | Slightly soluble |
| Purity | Typically ≥98% |
| Storage Temperature | Store at 2-8°C |
| Smiles | c1cc(c(cc1O)N(=O)=O)F |
| Inchikey | FDFNRYFVIUXSTL-UHFFFAOYSA-N |
As an accredited 5-Fluoro-2-Nitrophenol,2-Nitro-5-Fluorophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | A 25-gram amber glass bottle with a secure screw cap, labeled "5-Fluoro-2-Nitrophenol, 25g" and hazard warnings. |
| Shipping | 5-Fluoro-2-Nitrophenol (2-Nitro-5-Fluorophenol) is shipped according to hazardous materials regulations. It is typically packed in tightly sealed containers, cushioned to prevent breakage, and clearly labeled for chemical content and hazard class. Transport is restricted to authorized carriers trained in handling dangerous goods, ensuring compliance with safety standards. |
| Storage | 5-Fluoro-2-Nitrophenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area, away from sources of ignition, heat, and direct sunlight. Keep away from incompatible substances like strong bases and reducing agents. Avoid moisture and store at room temperature. Label the container clearly and follow all relevant safety protocols and chemical storage regulations. |
Competitive 5-Fluoro-2-Nitrophenol,2-Nitro-5-Fluorophenol prices that fit your budget—flexible terms and customized quotes for every order.
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On our production lines, every batch tells a story. 5-Fluoro-2-Nitrophenol—sometimes referenced on research benches as 2-Nitro-5-Fluorophenol—doesn’t just come from a supply chain or catalog order. Real hands, tried processes, and rigorous years of production experience shape each shipment. This compound isn’t some faceless specialty; it comes from dependable factory routines. Through repeated cycles, we have found the quirks, strengths, and tradeoffs that matter in the real world, where performance drives choice.
Fluorinated nitrophenols belong to a niche corner of aromatic intermediates. Their molecular blueprint—two substituents, fluorine and nitro—gives a unique fingerprint. 5-Fluoro-2-Nitrophenol distinguishes itself with a combination not commonly found in broader commercial chemistry stocks. It takes precise conditions to introduce the fluoride and nitro groups exactly where research or industrial chemistry needs them; even a small shift in synthesis means differences in reactivity, purity, and stability.
Unlike some common nitrophenol derivatives, our method avoids side-product pitfalls that can complicate downstream chemistry. Over dozens of batches, we encountered mysterious peaks in GC traces and found subtle color changes in drying cakes that revealed problems invisible under standard protocols. Open conversations with customers and internal reviewers pushed us to refine purification and drying. As a result, the product steps into higher-end synthetic applications without burdensome byproduct profiles.
Consistency goes beyond purity on a spec sheet. Our factory saw how slight fluctuations in reflux temperature or changes in crystallization solvents made more impact than technical literature hinted. When we raised reaction control to tighter margins, our output held bright yellow crystals, bulk density stayed in the predicted range, and the melting point landed in a tight window. Our typical lots reach greater than 98% chemical purity by HPLC, with impurities identified and flagged from hard-won library data.
Water content once drew complaints, especially when downstream users incorporated the phenol as a building block for pharmaceuticals or advanced materials. We now finish each lot with controlled vacuum drying, validated by Karl Fischer titration on every packout. Our product shows low residual moisture—commonly under 0.2% w/w—and avoids lumping or caking in transit. For labs and manufacturing sites, these details make a difference: no more heavy scraping or inconsistent dissolving at the start of a new process.
Particle uniformity cannot be left to chance with our volumes. Batch milling after crystal formation, followed by sieving through standard mesh ranges, keeps flow reliable for charging reactors. In earlier years, we found too-coarse cuts led to slow dissolving that cost production hours. Customers working at kilogram or higher scales gave direct feedback that prompted changes, and today our lots move smoothly from storage drums right into weighed scoops or automated feeds.
The main demand driver isn’t curiosity or academic exploration—it’s purposeful synthesis. 5-Fluoro-2-Nitrophenol acts best as a key intermediate rather than a curiosity. Agrochemical firms lean on it for preparing herbicide scaffolds with improved environmental profiles. The fluorine atom enhances the metabolic stability of minerals and bioavailable agents, often tuning performance just enough to create a novel patent landscape. We have run toll campaigns for partners who value high-purity intermediates as the foundation for new pesticides with clear regulatory trails.
Pharmaceutical researchers depend on this compound when shifting core scaffolds towards better potency or metabolic fate. The dual presence of nitro and fluorine gives medicinal chemists new synthetic routes for late-stage diversification or ring substitution that other nitrophenols can’t match. In our own work, we saw the product’s value as a launching pad for protected phenolic ethers, which then move through staged hydrogenations or further halogenation. Every user wants a supply chain ready-made for quick customizations, and our shopfloor adjustments keep up.
Materials chemistry explores new uses with every year. Demand has grown from customers focused on dye intermediates, electronic film modifiers, and photolithography reagents. The electron distribution from both the nitro and fluorine groups alters UV absorbance and electron transfer properties in polymers and specialty inks. We regularly get requests for tailored particle sizes or adjuvant blends for faster incorporation in resin systems. Each request teaches us a little more about the compound’s adaptability—lessons we fold into new production runs.
The market sees generic nitrophenols from many origins. Some ship with broader cuts or multiple isomer contamination. Others advertise loose fluorination or skip the nitro group entirely. Our 5-Fluoro-2-Nitrophenol stands apart through methodical batch verification; targeted NMR and mass spectrometry checks confirm the isomeric assignment and flag deviations. Last year, a runtime issue forced an emergency batch rework—rather than shipping a problematic lot, we stopped, reprocessed, and dialed in the parameters.
We do not substitute one isomer for another under pressure to meet quotas. 2-Nitro-5-Fluorophenol is another name for the same target compound—straightforward, with the substitution sites clear in every spec and shipment label. Subtle differences in process routes can yield trace-byproducts. Some competitors cut corners on drying or purification, leaving residues that influence downstream catalyst reactions or analytical reads. Our own complaints about failed late-stage coupling reactions taught us to raise the bar, not chase short-term savings.
End-users in regulated sectors want every drum to come from accountable hands. They do not want surprises, either with unexpected contaminants or mismatches in expected physical form. We saw with our own eyes how uncertain sourcing or split-lot blending caused logistical nightmares or batch failures—issues that can ripple all the way to a commercial product recall. Our team stands by every batch, keeping direct documentation and traceability for spot audits or root-cause investigations. Trust does not grow overnight, but years of traceable shipments proved its worth during customs checks and partner reviews.
Quality assurance at our factory involves technical work and honest reporting. Our QC staff developed a reference spectrum database based on years of observed variability. They catch deviations before anything leaves the plant. Audits, both internal and from our partners, forced improvements and validated our drive to keep the process sharp. Customer feedback goes straight to the engineering team—if something can be done better, our whole line adjusts. This culture started with a handful of skilled chemists and grew as our business expanded.
Factories, not just formula sheets, taught us to respect this compound. The nitro group brings risks typical to aromatic nitro compounds, while fluorinated materials require protective measures to avoid skin and respiratory exposure. Our plant protocols came from rounds of trial and adaptation. We found out early how dust control, exhaust filtration, and temperature management shield both the workforce and the final product. Stories circulate about near-misses—every experienced handler knows these lessons are bought, not borrowed.
We package only in certified, moisture-free containers. Each pail or drum gets seals and batch records updating throughout its journey. Shipment routes optimized for temperature stability, with holding and offloading tracked to avoid excessive heat that can lead to product breakdown. Onsite storage recommendations stem from real warehouse checks, not just theoretical guidance. These habits mean each kilo delivered is ready to perform, not compromised by weeks in poor conditions.
Our most detailed process revisions started with a late-night customer call or a flagged issue during a product launch. Scientists and process engineers teach us just as much as we help them. Feedback on handling, solubility, or even packaging design led to changes on our line—every improvement traces back to a tangible problem experienced in a customer plant or lab. We do not see these relations as sales but as partnerships. Better product characteristics feed into higher success rates downstream.
Team meetings after big projects turn into open forums. Staff from synthesis, quality control, packing, and shipping share what worked, what failed, and how new customer needs shape next runs. Training for new hires includes the real stories: a ruined batch because of missed drying step, or how a slightly different mesh cut solved a scale-up bottleneck months before public launch. These stories drive home that making a compound for real industry use is a living process—not a checkbox on a compliance form.
Over years of operation, we watched the market’s requests change. Purity standards have climbed, though practical demands sometimes matter more: consistent powder properties, improved solubility, stable shipping, clear documentation. We continue to refine our crystallization and purification steps based on new research and better analytics. R&D staff tie up daily operations with development work, asking if a process tweak might shave hours off production or reduce solvent losses.
New regulations and certifications create both hurdles and opportunities. Our drive to anticipate coming norms—whether those relate to environmental discharge, worker safety, or traceability—means we adapt before outside pressure forces our hand. Projects to recover waste streams or minimize reagent use came out of shopfloor suggestions. These steps let us offer a product that stands up during audits and strengthens our customer network. As industries evolve, so do our priorities, but the grounding in real facility needs never changes.
5-Fluoro-2-Nitrophenol won’t be the centerpiece of every chemical catalog. For our team, gravitating towards specialty synthesis, it has been a workhorse that demands focus and diligence. Years in production taught us that cutting corners doesn’t stay hidden; problems show up sooner or later—sometimes as a lost customer, sometimes as a production stoppage costing jobs and trust. We keep learning how small improvements—careful reaction control, stronger documentation, better warehouse flow—build a foundation for sustainable supply.
Businesses looking for this product rarely ask only about price or paper specifications. They want a partnership with a source they can trust to deliver the same batch profile month after month. The mixture of science, hard work, and mutual respect shapes every order we fill. This attention to detail, cultivated by experience and direct contact with users, helps our product meet more than just minimum quality—it fills a true need for reliability in a shifting chemical landscape.
| Aspect | Detail |
|---|---|
| Chemical Name | 5-Fluoro-2-Nitrophenol (also known as 2-Nitro-5-Fluorophenol) |
| Key Features | Consistent batch quality, low residual moisture, tightly controlled particle size, robust traceability, direct manufacturer support |
| Primary Uses | Agrochemical intermediates, pharmaceutical synthesis, dye and materials science |
| Physical Form | Yellow solid, controlled powder or crystalline granules |
| Purity (Typical) | >98% HPLC, minimal isomeric or inorganic residue |
| Packing | Drums or pails, moisture-sealed, lot traceable, batch-specific QC documentation |
| Distinguishing Features | Factory-originated, high reproducibility, responsive manufactuer-backed improvements, no dilution or isomer substitutions |
Producing 5-Fluoro-2-Nitrophenol goes deeper than chemical reactions under ideal conditions. Our practice proved that fine-tuned operations, hands-on troubleshooting, and unbroken attention to honest process drive value to every user. This product reflects all the lessons learned from practical factory work, feedback-driven change, and a shared vision for quality that looks beyond the next order. As new challenges and customer requirements arise, we stay committed to providing more than a supply—we offer deep manufacturing experience with every kilogram we produce.
