|
HS Code |
584705 |
| Cas Number | 842-07-9 |
| Molecular Formula | C8H10N2O4 |
| Molar Mass | 198.18 g/mol |
| Appearance | Yellow to brownish powder |
| Melting Point | 158-162°C |
| Solubility In Water | Soluble |
| Purity | Typically >98% |
| Usage | Hair dye intermediate |
| Boiling Point | Decomposes before boiling |
| Ph Value | Approx. 7 (1% solution in water) |
| Synonyms | 4-(2-Hydroxyethylamino)-3-nitrophenol |
| Storage Temperature | Store at room temperature |
| Odor | Odorless |
As an accredited 4-Hydroxyethylamino-3-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The chemical is packaged in a 100-gram sealed amber glass bottle with a tight cap, labeled for laboratory use only. |
| Shipping | 4-Hydroxyethylamino-3-Nitrophenol should be shipped in tightly sealed, chemical-resistant containers, clearly labeled, and protected from light and moisture. Transport must comply with relevant hazardous material regulations. Ensure appropriate cushioning, secondary containment for spill prevention, and inclusion of safety data sheets. Avoid extreme temperatures and handle with personal protective equipment during shipping. |
| Storage | **4-Hydroxyethylamino-3-Nitrophenol** should be stored in a tightly closed container in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and acids. Protect from light and moisture. Ensure appropriate labeling, and use secondary containment to prevent spills. Store at room temperature and avoid sources of ignition, as chemical dust may be hazardous. |
Competitive 4-Hydroxyethylamino-3-Nitrophenol prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615380400285
Email: sales2@liwei-chem.com
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There is no shortcut to reliable results in the chemical industry, especially when supplying ingredients for demanding applications. Over years of manufacturing experience, each batch and every drum we produce goes through scrutiny because our customers have high expectations, and every error means lost time and unnecessary cost on both sides. 4-Hydroxyethylamino-3-Nitrophenol is not just another item in our catalogue. Its importance stretches beyond its place as an intermediate or a secondary ingredient—it anchors the shades and performance profiles of personal care products, coloring systems, and technical dyes. That makes thorough control of quality and consistency more than a box-ticking exercise; it is a commitment written into the routine of our daily work.
Manufacturing this chemical involves precise steps and an uncompromising approach to monitoring impurities. The raw ingredients, storage, and process conditions all matter because even a small variance changes the end result. Anyone working in this space comes to appreciate the big role played by incoming supply chain consistency and careful reaction monitoring. We use years of accumulated factory data to keep batch variations to a minimum. The chemical structure—2-(4-hydroxy-2-nitrophenyl)amino)ethanol—comes with a sensitivity to temperature, moisture, and handling processes. Consistency is not only about color strength or solubility. It also means cleaner product with less dust or byproduct, reducing process headaches during our customer’s formulation or blending stages.
We see requests for different grades, purity levels, and physical appearances for the same chemical. Sometimes it’s a request for higher-purity crystals; other times, it’s a need for a more granular or flowing form that fits the customer’s feeding or dispersing equipment. In actual operations, we find that some customers report dosing problems, leading to shade stability or dissolution glitches. These stories help us target not just purity, but also supporting parameters like bulk density and flow properties. Our routine checks cover not only the main assay, but also trace metals, unreacted starting material, and known side-products. Instead of simply selling on spec sheets, we ask for feedback to see how the product behaves in real-world conditions, whether in a South American manufacturer’s hair color blending room or a European small-batch colorant process.
Colorant intermediates are a crowded field, yet 4-Hydroxyethylamino-3-Nitrophenol stands out for some important reasons. Its nitro group—in combination with the hydroxyethylamino moiety—offers broad compatibility in oxidative dye processes. In permanent and semi-permanent hair dyes, this intermediate brings a predictable bluish to light yellow hue, resisting batch-to-batch drift and fading under processing conditions. Our teams have worked side by side with customers addressing issues such as color bleeding, rapid darkening, and off-odors, all tracked back to variances in this precise molecule.
Other commonly encountered intermediates may offer different color results or processing flexibility but don’t fare as well in applications needing stability under repeated exposure to hydrogen peroxide, high pH, or rapid heating cycles. We’ve seen formulators attempt to substitute this intermediate with alternatives in a bid to cut costs, only to face inconsistent salon-to-salon color profiles or shelf-life problems. That’s the lesson: reliability is rooted in chemical stability under stress conditions, which depends not only on a molecule’s core structure but on the details of its manufacture.
We currently focus production on the model with CAS number 3844-45-9. Decades of hands-on work keep teaching us the same lesson: purity targets matter, but so do side products and moisture. Market demand overwhelmingly favors batches in the 99 percent assay range, with trace impurity levels lower than one in a thousand. Throw in the demand for batch-to-batch uniformity in hue and granulation, and it becomes clear that achieving this year after year is not a matter of button-pushing automation. It is a people-driven, detail-oriented process—checking every tank, recording pH at every step, cleaning lines meticulously between batches. When mistakes do slip through (nobody is immune to the occasional hiccup), rapid trace-back and corrective reporting are non-negotiables.
Our plant specifications lean towards a fine crystalline form with off-white to light yellow appearance, a melting range that fits customer blending needs, and capped moisture content to prevent clumping. Each of these parameters was built directly out of customer feedback and post-delivery follow-ups. Part of what we do differently is adjust storage and delivery recommendations in real time, based on not just lab data but actual weather, shipment route, and customer handling capabilities.
Years ago, a major multinational hair dye producer came to us with concerns about the unpredictable color drift occurring across their regional factories. A deep dive into process logs and sample archives zeroed in on differences in residual moisture and trace nitrosamine levels in dye intermediates purchased from a mixture of local and overseas sources. Adapting control checks based on their findings, we eliminated a critical step responsible for one such side product. The end result was not only consistent dye shade, but a clear improvement in safety documentation sent to their regulatory departments.
Small- and medium-sized customers benefit from this discipline as well. One startup from Northern Europe needed micro-batches for new vegan hair color blends. They had run into problems with a distributor-sourced intermediate, which left their prototype batches with grainy precipitates and inconsistent color. Working directly with our plant allowed a switch to a tighter-mesh filter option at the packing stage and better rinsing before final drying. Their issue was resolved in the first test run of our modified product.
This chemical commonly plays an integral role as a coupler in oxidation dye systems. In the context of hair color, its function is to combine under alkaline oxidative conditions to deliver lasting color with minimal off-shade production. Over the past decade, we have seen increasing attention paid to residue levels, carry-through impurities, and allergen reporting. Our technical staff assists both established and up-and-coming companies by providing additional characterization—HPLC traces, infrared spectra, and, on occasion, pilot-scale custom blends for process development.
Looking beyond hair dyes, there is also some niche usage in colorant technologies for textiles and technical markers. Usually, these applications call out for higher color fastness and compatibility with a broader range of substrates. Our involvement doesn’t end with a bulk shipment—often, teams ask for small pilots, alternative particle sizes, or stability reports to address concerns issued by their internal development labs.
Not every nitrophenol or amino-alcohol is interchangeable, despite similarities in chemical structure. Our specific grade of 4-Hydroxyethylamino-3-Nitrophenol delivers a unique reactivity balance thanks to the presence and location of its nitro group, which ensures a bluish color shade and higher resistance to oxidative breakdown, especially under aggressive formulation conditions. Many alternative products we’ve come across in the past carry higher levels of secondary amines or residual sulfur, which not only reduces shelf stability but can impact regulatory assessments related to nitrosamine potential. Our process has evolved to address these hotspots: by using high-clarity solvents and optimizing crystallization steps, we drive both color consistency and low impurity content.
Our teams perform ring tests and accelerated aging tests on each raw material batch. In this way, we catch variance before it shows up at the formulator's end. This chemical’s distinctiveness lies as much in the invisible details—lower levels of unreacted base, reduced hydrolysis tendency during storage, and absence of off-odors—as in the obvious ones like hue or particle size.
Current demand for improved transparency and tighter residue thresholds makes batch documentation and safety support compulsory, not optional. The regulations covering this category of dye intermediates grow more complex each year, with stricter limits from regulatory agencies in Europe and Asia. Because of this, every delivery includes test data covering not only main assay but heavy metals, known byproducts, and allergen profiles, ensuring that customers face fewer surprises during their own audits. In our own practice, we regularly update our internal standards to align with upcoming changes—often going beyond legal minimums to future-proof new batches.
Not every part of producing 4-Hydroxyethylamino-3-Nitrophenol follows a script. Seasonal changes sometimes lead to raw material variations; we have experienced situations where a monsoonal shipment of precursor had a threefold moisture spike, risking the onset of unwanted side reactions. Problems like this become practical only when encountered in real manufacturing circumstances, and solutions sometimes require creative, real-time responses—switching to alternative containers, using extra drying, or splitting a batch to minimize risk. We take customer feedback seriously, not just during formal audits but during informal plant visits and troubleshooting calls.
The biggest value we provide is not in a “perfect” assay or a generic molecule but in a service culture based on listening and responding as situations arise. As customer requirements get more challenging—whether for lower irritation formulations, hypoallergenic blends, or higher technical purity for specialty markers—the lessons of day-to-day chemical manufacturing remain the same: success comes from knowing where issues crop up and facing them early. For our part, keeping our staff trained, our equipment updated, and our dialogue open ensures success as new trends appear.
We are seeing a growing pull toward sustainable chemistry and low-impact manufacturing. Customers question not only product purity but also carbon footprint, waste minimization, and the traceability of precursors. Responding here means making clear investments: optimizing reaction yields, upgrading waste treatment, and moving toward renewable energy in plant operations. We’re participating in collaborative projects targeting wastewater recycling and capturing solvent vapors, which further reduce the material impact per delivered kilogram.
Digitalization is making its way to our industry as well. From computer-monitored reaction progress to cloud-based batch histories and customer portals, every link in the process becomes more transparent and more secure. Customers log requests for custom certificates online, receive historical spectra for specific lots, and engage in real-time troubleshooting with our lab teams. This ongoing process of change raises the bar, not just for us, but for anyone making specialty chemical ingredients.
Looking back at the path our plant has taken in producing 4-Hydroxyethylamino-3-Nitrophenol, it is clear that the basics still matter most: reliable supply, technical know-how, and attention to every step, from raw materials to package labeling. We will keep adapting to the market’s needs, using the lessons from the past and the challenge of new regulations and tighter user requirements. By working hand in hand with customers, industry partners, and our own teams, we aim to deliver not just the chemical, but the confidence it brings with every drum and every formulation.
