|
HS Code |
224752 |
| Iupac Name | 4-(4-Nitrophenyl)phenol |
| Molecular Formula | C12H9NO3 |
| Molar Mass | 215.21 g/mol |
| Cas Number | 3098-15-7 |
| Appearance | Yellow crystalline powder |
| Melting Point | 172-175 °C |
| Solubility In Water | Slightly soluble |
| Density | 1.32 g/cm³ (approximate) |
| Pka | 9.8 (for phenolic group) |
| Smiles | C1=CC(=CC=C1C2=CC=C(C=C2)NO2)O |
| Inchi | InChI=1S/C12H9NO3/c14-12-6-10(7-13(15)16)2-4-11(12)8-3-1-5-9(8)9/h1-7,14H |
As an accredited 4-(4-Nitrophenyl)Phenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle containing 25 grams of 4-(4-Nitrophenyl)phenol, sealed with a screw cap; labeled with hazard and identification information. |
| Shipping | 4-(4-Nitrophenyl)phenol is shipped in tightly sealed, chemical-resistant containers to prevent leakage and contamination. The package is clearly labeled as hazardous, complying with relevant transportation regulations. It should be handled with care, protected from light and moisture, and shipped at ambient temperature unless otherwise specified by safety guidelines. |
| Storage | 4-(4-Nitrophenyl)phenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizers and bases. Protect from direct sunlight and sources of ignition. Store at room temperature and ensure proper chemical labeling. Use appropriate secondary containment to avoid spills or contamination. Follow all relevant safety regulations. |
Competitive 4-(4-Nitrophenyl)Phenol prices that fit your budget—flexible terms and customized quotes for every order.
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Years of practical benchwork and process scale-up have formed our approach to 4-(4-Nitrophenyl)Phenol. This compound keeps showing up in tasks where selectivity and robust performance matter, especially in organic syntheses and technical applications that demand molecular precision. From our reactors, we’ve watched this molecule operate as both a functional intermediate and a key structural element. By controlling reaction conditions and raw material sources, we maintain consistency from one batch to the next. Purity targets regularly exceed 98%, and our process avoids cross-contamination, so labs and production engineers know what to expect with every order.
Many suppliers buy standard intermediates and repackage them. We don’t work that way. Our chemists build 4-(4-Nitrophenyl)Phenol starting from core aromatic materials in our own facilities, using validated procedures grounded in kinetic control and stringent purification. Nitration steps in aromatic chemistry can be tricky—over-nitration ruins product and wastes time. Our process tightly modulates nitration rates and temperature profiles to get high selectivity. For phenol coupling, we rely on time-proven catalysts rather than experimental shortcuts, which reduces risk in scale transitions. Chemical filtration, solvent stripping, and endpoint analysis run daily in our QA. During pick-up of solid product, we use in-house screened vacuum-drying to ensure residual solvents never climb above safe industrial limits.
Where discussion about purity and assay often sounds abstract, in the factory and the lab these numbers make or break projects. Every drum or bottle we send out bears a batch record referencing HPLC and GC chromatograms as well as infrared spectra fingerprinting. In our view, blending materials to "meet the average" just introduces variability. So our product does not change lot-to-lot in tint, melt, or titration. The typical sample looks like a pale yellow crystalline powder, melting right around 170°C. Moisture, checked by Karl Fischer, falls well below 0.5%. Packing into lined kegs or antistatic drums protects against both humidity and static buildup. We mark each package with QR-coded lot numbers for traceability. Quality assurance doesn’t stop with a checklist; it involves understanding how the molecule behaves in end uses, and feeding that feedback back into process improvements.
End users in fine chemical synthesis, resin modification, and specialty pigment production select this compound for its electronic properties as well as its reliable reactivity in coupling or cross-linking. By sitting at a para-position relative to both phenol and the nitro group, this molecule introduces unique electron distribution compared to its ortho- or meta-substituted relatives. That translates to predictability in functionalization steps. For instance, researchers in pharmaceutical R&D turn to it for controlled nitration and selective cross-coupling reactions when other intermediates stall or produce excessive side-products. We’ve fielded calls from synthesis chemists troubleshooting unexpected color issues, only to discover inferior grades from other sources left minute oxidized byproducts behind. Our material, consistently clean, supports chromatographic purification and downstream functionalization because the trace profile does not change unpredictably. The feedback loop between our production team and customers keeps our insights relevant as market needs shift.
Not all nitrophenyl derivatives play the same role in synthesis. Low-grade suppliers can leave aromatic starting material residues in the product, skewing color and causing haze in final applications. Recrystallized grades might remove some impurities but also sometimes lower the active content, especially if crude isolation introduces excess wash solvents. We take care to foster a balance: our approach strips out colored and ionic impurities while preserving the molecular integrity of the phenol core. In phenolic resin modification, the position and purity of the nitro group change cross-link density. Out-of-position isomers hydrate poorly, or leave uncoupled groups, which weakens the mechanical profile of the resin. Demand for a high-purity para-conjugated system is strongest from teams building high-performance coatings and adhesives, where small differences in reactivity show up as faulty curing or variable film strength. Our chemists track and understand these challenges, optimizing for specifications that real industrial operators raise, not just what a reference handbook says.
Over the years, custom applications in lightfast pigments, electronic polymers, and agricultural intermediates started relying on our 4-(4-Nitrophenyl)Phenol because of batch-to-batch reliability. A process engineer in a coatings plant once shared that unplanned downtime traced to poorly solubilized nitro intermediates from multiple sources; now, their supplier qualification process regularly picks our compound for upstream clarity. Consistency is not just a marketing catchword. Our factory makes use of closed handling and in-process checks that catch any deviation in melting point or color before the product leaves the plant. With every material release, our lab runs spot checks—GC-MS for major and trace compounds, IR for fingerprint regions—logging results over years for any deviation from historical performance. This historical data lets us spot and address subtle shifts, such as catalyst aging or upstream solvent quality issues.
In the field, practical issues sometimes differ from what a specification sheet sets out. For one client, minute levels of iron entering the batch at a supplier’s plant caused resin color instability—something that only showed up when production scaled up beyond pilot. After switching to our product, which runs through nonferrous equipment, yellowing disappeared. Another case involved issues in downstream coupling reactions producing unwanted dinitro byproducts; tighter fractionation in our process helped minimize this. Whether the feedback comes from custom organic synthesis labs, industrial resin makers, or pigment formulators, the common ask has always been the same: dependable, high-purity product that acts the same every time. As engineers ourselves, we build those learnings into regular SOP reviews and non-stop dialogue between plant chemists and customers.
We recognize that more end-uses now require transparency in both composition and trace contaminants. Our quality team builds annual analytical summary reports covering traces—metals, chlorinated residues, and possible organic side-products—on demand. Since the molecule’s structure and potential downstream uses often fall under regulatory scrutiny, we maintain a clear trail for every lot, dating from raw material intake through final dispatch. While we focus production on industrial and R&D-scale quantities, we also regularly engage with labs on documentation questions, offering full disclosure on our synthetic route and testing protocols. Analytical methods—HPLC, GC, IR spectra—are available directly, not hidden behind red tape.
Process optimization happens in small, routine steps, not headline-grabbing quantum leaps. We continually invest in plant upgrades—cleaner lines, real-time monitoring, better filtration—to incrementally drive quality gains. Sometimes improvements come from customer dialogue: after a pigment formulator noted better performance from slightly drier material, we adjusted drying times and monitored results over six months before making the change permanent. At other times, regulatory changes in solvent usage push us to develop lower-residual alternatives, especially for customers in electronics and specialty coatings who must meet ever-tighter limits on trace organics.
Across decades, we have watched competing products with inconsistent analysis or questionable process control trigger lost batches and rejected drums. The hidden costs of failed intermediates are significant: wasted reactor time, downstream scrap, customer delivery delays, and process restarts. Companies sometimes cut corners with off-the-shelf intermediates. That practice saves pennies upfront and risks thousands later in rework or client dissatisfaction. Our ethos as a manufacturer remains rooted in controlling every step: from incoming reagent analysis through final QC and supported beyond the point of shipment. This discipline shows up in results at customer plants—less downtime, fewer batch rejections, and a laboratory staff that doesn’t spend weekends troubleshooting impurities.
Some facilities offer similar nitrophenylphenol isomers, notably those with nitro groups in less reactive positions. While technically serviceable, those variants often require adapted conditions in cross-linking or functionalization reactions. These subtle differences translate into greater uncertainty or the need for extra purification. High-end applications—such as electronics, photoresists, and pharmaceutical active intermediate synthesis—demand reactivity and reliability that weaker grades simply don’t supply. Both industrial and laboratory teams aiming for specific substitution patterns or steric effects pick our product because of its consistent structure and reactivity, which avoids trouble with side-reactions. Our direct synthesis route, run under controlled atmosphere and with recycled solvent recovery, also limits environmental impact compared to less monitored operations, an aspect customers grow more conscious of year by year.
Long-term contracts with global manufacturing customers underscore a shift: buyers increasingly scrutinize supply chain resilience, not just price or shipping speed. By synthesizing and packaging 4-(4-Nitrophenyl)Phenol ourselves, we retain flexibility and transparency. Surges in demand, raw material interruptions, or custom requirement changes land directly with our technical and production teams, not third-party buyers. As a result, we ship to tight timelines, support technical Q&A, and adapt specifications—not because a trader relays the message, but because our line chemists run the reactors and know how to tune the process themselves. For users with unique requirements—tailored particle size, extra screening, or specific wetting agents—we work overtime to adapt, test, and validate before scaling. These process investments mean our partners avoid the uncertainty of middlemen, and our team delivers more than just raw material—they provide responsive technical partnership.
Direct chemical manufacturing imposes obligations that distributors can’t appreciate: safe handling, real-time hazard monitoring, and strict compliance with waste management for both worker protection and community safety. In producing 4-(4-Nitrophenyl)Phenol, our process control extends to air emissions, solvent recovery, and reaction sequence safety. End users receive product sealed, labeled, and accompanied by clear handling advice from people who have handled every step hands-on. Our background managing real-life plant risks also keeps us focused on incremental process safety improvements, whether by installing new scrubbers or automating liquid transfers to minimize exposure.
Researchers, industrial chemists, and materials engineers still find new uses for classic intermediates. This product now sees trial runs in advanced diagnostic dye synthesis, smart coating formulations, and custom electronics. Rather than watching the field from the sidelines, we engage with project teams—supplying samples, reviewing application notes, and modifying grades in response to feedback. In specialty markets, project needs sometimes change on short notice, particularly in pharmaceuticals or electronics; our in-house synthesis and packaging allow rapid turnaround.
Supply chain disruptions and shifting regulatory landscapes keep raising the bar. By controlling our own process, supply, and outbound chain, we manage risks better than those relying on uncertain third-party facilities. Engineers and project leaders want chemistry that doesn’t cause surprise disruption. When our team answers technical questions or supply planning calls, they do so pulling from daily plant experience, not a generic script. Uncertainty in specialty chemical supply often breeds downtime, slow troubleshooting, and blown budgets. Our goal: to remove that uncertainty. With full batch history, immediate certificate access, and responsive real-life chemists instead of an impersonal help desk, we deliver more than product.
Every kilogram leaves our site with the benefit of not only analytical precision, but years of small process improvements passed from plant veteran to new chemist. Our approach to 4-(4-Nitrophenyl)Phenol isn’t just about synthesis and shipping. It draws from accumulated knowledge—error logs, customer feedback, careful study of reactivity, practical troubleshooting. As regulations tighten, markets evolve, and applications diversify, we keep tuning our process to deliver what real-world users expect: safe, clean, timely material that keeps projects moving.