|
HS Code |
932798 |
| Productname | 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol |
| Casnumber | 4316-54-9 |
| Molecularformula | C19H16O4S |
| Molecularweight | 340.40 |
| Appearance | White to off-white powder |
| Purity | ≥98% |
| Meltingpoint | 184-188°C |
| Solubility | Slightly soluble in DMSO and methanol |
| Storagetemperature | 2-8°C |
| Synonyms | 4-(Benzyloxy)-4'-hydroxydiphenyl sulfone |
| Smiles | C1=CC=C(C=C1)COC2=CC=C(C=C2)S(=O)(=O)C3=CC=C(C=C3)O |
As an accredited 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The chemical is packaged in a sealed amber glass bottle, labeled 25 grams, with hazard warnings and product identifiers clearly displayed. |
| Shipping | 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol is shipped in secure, airtight containers to prevent contamination and moisture exposure. Packaging complies with chemical transport regulations, ensuring safe handling and labeling. The product is typically transported at ambient temperature, with appropriate documentation and hazard information included to guarantee safe and compliant delivery to the destination. |
| Storage | Store 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol in a tightly sealed container, protected from moisture and direct sunlight. Keep in a cool, dry, and well-ventilated area, preferably at room temperature. Avoid storing near incompatible substances such as strong oxidizing or reducing agents. Properly label the container and ensure access is limited to trained personnel using appropriate personal protective equipment (PPE). |
Competitive 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol prices that fit your budget—flexible terms and customized quotes for every order.
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Manufacturing a specialty chemical like 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol means answering to demands from advanced research, pharmaceutical development, and fine organic synthesis with accuracy and reliability. Having produced this compound at scale for years, we recognize that details matter—from the choice of raw materials to meticulous final product checks. This product stands apart due to the way it integrates functional groups, and our experience has underscored repeatedly why stability, consistency, and purity drive its success in challenging applications.
We have developed several process routes, settling through repeated trial and optimization on a method that strikes a balance between yield, safety, and environmental responsibility. The product we supply typically exceeds 99% purity by HPLC, which we routinely confirm batch by batch, because variation clogs up formulation flow or causes headaches on pilot scale-up for researchers. Our process avoids excessive reaction temperatures and employs solvents that minimize impurity profiles, keeping heavy metal content and byproduct sulfonates below detectable thresholds. Each lot comes in crystalline form, which resists moisture pickup and simplifies both storage and precise weighing for end users.
Researchers and process chemists frequently tell us their headaches—batch-to-batch fluctuations, oily residues, off-colors, or suspicious odors. Over the years, we’ve learned that supplying the compound as an off-white to pale yellow solid, free from visible particulates and with a well-defined melting point, makes downstream reactions much more predictable. Physical characteristics translate into better solubility and dispersion during formulation, and the spectral data matches published reference standards. We use proton and carbon NMR, FTIR, and mass spectrometry on every batch as part of our routine, not because it’s required by regulation, but because it spares our clients from unexplained side products later in the process.
Purity levels below 98% or minor residual solvents can lead to unpredictable reactivity, particularly in coupling steps or sensitive catalytic reactions. Customers who’ve come to us after experiencing issues elsewhere report frequent purification bottlenecks—a loss of yields, wasted time, and added costs. By controlling key reaction steps and thorough washing procedures, we supply this compound ready for immediate use, lowering risks of failed synthesis on multi-gram or kilo-scale runs. Our entire workflow—from raw material sourcing to crystallization and packaging—relies on validated controls. Instead of focusing only on nominal specifications, we pay attention to hidden parameters like chloride and sulfate residuals, which can undermine advanced material properties.
The largest volume use of 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol sits in the fine chemical and pharmaceutical intermediates sector. Whether forming sulfonamide linkages for candidate therapeutics or acting as a protected phenolic building block in multi-stage syntheses, this compound’s stability under a range of pH conditions helps ensure high conversions. We’ve supplied this material into projects seeking to scale up enzyme inhibitors, anti-inflammatory agents, and even specialty polymers designed for electronics. Its sulfonyl group resists unwanted side reactions, protecting more vulnerable functions as elaborate molecular architectures get built up. The benzyloxy substitution offers opportunities for further selective modifications downstream, making it especially valuable versus simpler analogs.
Over time, we’ve encountered clients who started with generic sulfonylphenols, only to discover that variable substitution patterns create unintended consequences on reactivity and selectivity. Less sophisticated suppliers may offer compounds with similar names or structures, but key differences in the position or nature of functional groups completely alter both handling and final outcome. For example, unprotected phenols often lead to side-product messes during alkylation, while isomeric products can shift reactivity even when simple functional group counts appear identical. Our direct experience confirms that the benzyloxy group in this molecule shields reactive positions until intentional deprotection, aiding process reliability.
Additionally, older grades from some sources feature inconsistent batch color, sticky or hygroscopic residues from crude crystallization, or questionable assay techniques limited to TLC or outdated melting point apparatus. Laboratories who switched to our material have reported a reduction in column purifications, higher product yields, and more robust analytic results. We openly share recent spectral data so clients can compare it against their own benchmarks, building confidence in the identity and quality each time. This transparency has helped distinguish our material from both resellers and small-batch producers whose controls may lapse.
Handling certain sulfonyl derivatives poses specific risks, from slow decomposition under acidic conditions to variable stability at elevated temperatures. Through experience, we have established packaging protocols using airtight, light-resistant containers that shield the compound from UV degradation and airborne contaminants. Our technical staff recommend dry storage at moderate ambient temperatures, with a full chain of custody maintained throughout transit. We make no claims to sidestep proper handling, as robust PPE and ventilation always play a role in both our plant and customer labs, but consistent quality means there are fewer surprises—no popping jars, discolored residues, or polymerized lumps.
We have responded to requests for bulk kilogram packaging and smaller research-use bottles, offering vacuum-sealed options to extend shelf life and maintain physical integrity. Each type of packaging has been tested in real shipping cycles, including periods of high humidity or customs delay, to confirm the material withstands common transport challenges. We also maintain an open line of technical support, not to troubleshoot regulatory matters, but to share our direct process knowledge when new applications or scale-up questions arise. More than once, sharing our hydrogenation protocol or tips for recrystallization has kept customer projects on track.
Today’s research and production landscape gets complicated by layers of brokers, each adding cost or uncertainty—sometimes even substituting sub-standard intermediates to increase margin. As the original manufacturer, our traceability goes straight from raw material procurement through every synthetic step, with electronic batch records and analytical checkpoints. Years of feedback have reinforced that sampling at every interstage stops most headaches before they occur, sparing our partners a frustrating lottery of variable purity and unconfirmed origins. We invite clients to audit our methods and to inspect retained samples for themselves if any discrepancy arises.
Staying close to the shop floor and listening to both our own staff and clients delivers practical insights that abstract supply chain diagrams never show. Only a specialty manufacturer sees how small changes in solvent grade, agitation, or crystallization time create lot-to-lot variation at real scale. This hands-on attention explains why high-throughput researchers return for repeat orders, and why pharmaceutical companies assign supplier codes to us after validation runs. Our workforce trains continuously, picking up small lessons from each production cycle and embedding these into daily practice.
Most specialty intermediates on the market don’t withstand scrutiny once real synthesis efforts begin. Trace aromatic contaminants, inconsistent polymorphs, and ambiguous labeling become clear obstacles at pilot or multi-kilo scales. We’ve watched projects lose weeks chasing down the cause of an unexplained spot in the NMR or a faint dusk color in what’s supposed to be a white powder. Our team draws from these stories by setting up process controls that alert us to deviations in real time, catching potential blips before drums leave our warehouse.
Clients have asked about cost and lead time, and our position remains straightforward. Direct supply from our plant shortens transit by weeks, simplifying customs paperwork and slashing the risks of chain-of-custody confusion. Volume production means we can quote stable prices and keep reserve stock of both raw materials and finished product, avoiding spikes that plague more speculative traders. We offer reliable re-stocking schedules, informed by both historic forecasts and ongoing client dialogue.
Our experience with this compound’s sensitive chemistry has bred a culture of openness. Every batch leaves our facility only with full release data, a policy shaped by hard-learned lessons rather than abstract compliance. Buyers have direct access to a single point of technical and commercial contact, someone who actually follows the synthesis progression rather than simply forwarding emails. Whether a new researcher or a long-time partner, clients receive direct answers, not formulaic boilerplate.
Feedback drives continual improvement. We routinely analyze returns or out-of-spec notifications, running side-by-side re-syntheses to drill down into root causes. Trace impurity profiling, even when not contractually required, has yielded actionable improvements affecting not just this product, but adjacent lines in our specialty sulfonyl and benzyloxy intermediates. Our accountability grows from each customer report—both good and bad.
Supply chain disruptions, fluctuating solvent markets, and sudden spikes in demand challenge every specialty chemical supplier. Over more than a decade, we’ve weathered shortages by qualifying multiple raw material suppliers and maintaining our own stocks of sensitive reagents under nitrogen. Rather than passing on every cost increase, we re-engineer routes for efficiency and increase stock planning. This means buyers see clear communication about lead times and pricing, with no last-minute surprises.
Environmental responsibility affects vendor selection, especially in the pharmaceutical and electronics sectors. We manage solvent recovery and waste neutralization on site, not outsourcing end-stage purification risks or disposal. This reduces potential for contamination and assures that each batch meets registration needs for sensitive end uses. Our site maintains up-to-date documentation for regulatory and quality audits, which supports global client deployment and cross-border compliance.
Our plant’s R&D team regularly collaborates with in-house and external chemists to extend the compound’s applications and performance. By analyzing customer project feedback, we’ve improved synthetic steps, streamlined purification, and identified next-generation analogs with varying benzyloxy and sulfonyl moieties tailored to evolving research demands. We welcome joint development discussions, contributing fresh samples and process data for collaborative synthesis efforts that might expand medical or material science boundaries.
Precision isn’t just a mantra; it’s built into how we approach raw material qualification, plant maintenance, and analytical calibration. We reinvest earnings into upgrading both production and analytic technologies, never resting on a legacy process just because it has proved adequate in the past. Our teams cross-train, share best practices, and monitor emerging literature for both risks and opportunities. Success means not just delivering on today’s orders, but anticipating tomorrow’s needs as techniques and standards continue to evolve within the advanced chemistry space.
Manufacturing specialty intermediates is rarely glamorous, but every kilogram gets produced as if our own lab would use it. Consistent, fully characterized 4-[(4-Benzyloxyphenyl)Sulfonyl]Phenol stands out through a commitment to organizational transparency, relentless quality checks, and a willingness to act on client input. By staying responsible and rigid with the details, we supply more than just a chemical—we offer a foundation on which researchers, manufacturers, and innovation teams can trust their next leap forward.