|
HS Code |
245055 |
| Cas Number | 84949-80-6 |
| Molecular Formula | C8H10N2O4 |
| Molecular Weight | 198.18 g/mol |
| Appearance | Yellow to brown solid |
| Melting Point | 160-165°C |
| Solubility In Water | Soluble |
| Purity | Typically ≥98% |
| Ph Value | Approx. 5-7 (1% solution at 20°C) |
| Synonyms | 2-(4-Hydroxy-3-nitrophenylamino)ethanol |
| Usage | Intermediate and dye ingredient in hair coloring products |
As an accredited 3-Nitro-4-Hydroxyethylaminophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Opaque amber glass bottle, tightly sealed, labeled with hazard warnings, contains 25 grams of 3-Nitro-4-Hydroxyethylaminophenol, for laboratory use only. |
| Shipping | 3-Nitro-4-Hydroxyethylaminophenol should be shipped in compliance with local, national, and international chemical transport regulations. Package securely in a sealed, labeled container with appropriate hazard documentation. Avoid exposure to heat, direct sunlight, and moisture. Ensure secondary containment to prevent spills, and include a material safety data sheet (MSDS) with the shipment. |
| Storage | 3-Nitro-4-Hydroxyethylaminophenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from direct sunlight. Keep it away from incompatible substances such as strong oxidizing agents, acids, and bases. Store at room temperature and protect from moisture. Ensure appropriate labeling and access only to trained personnel. Follow all relevant chemical safety regulations. |
Competitive 3-Nitro-4-Hydroxyethylaminophenol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615380400285 or mail to sales2@liwei-chem.com.
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Tel: +8615380400285
Email: sales2@liwei-chem.com
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Producing 3-Nitro-4-Hydroxyethylaminophenol requires a level of care that comes from years of working hands-on with complex aromatic intermediates. In our line, every batch reflects a hard-earned mastery over raw material sourcing, process stability, and stringent purification. For those in the dye industry, particularly in hair colorants, the need for consistent, high-purity ingredients forms the foundation of every successful product. Our team has spent thousands of hours in synthesis and quality control, working to reduce byproducts and minimize odorous residues—subtle details that operators and finished product designers notice right away.
The powdered forms we supply run pale yellow to light brown in color and range from fine to granular, with typical purity we maintain above 98%. We pay attention to the balance between particle size and flowability, as we learned—sometimes the hard way—how much even slight clumping can slow down automated mixing lines. Over the years, switching solvents, adjusting crystallization rates, and refining drying technique made differences not only in appearance but in storability and shelf life.
Our batches undergo HPLC and GC-MS checks at multiple stages, not just at the final step. Some customers ask why this matters. It matters because this chemical serves as a precursor in oxidative dye systems, especially in semi-permanent and permanent hair dyes, and impurities can trigger unpredictable color shifts or affect developer stability downstream. We track low ppm levels of key trace metals and watch for those reactive nitro partners that sometimes escape earlier purification. Operators in color labs have shared with us stories of foreign-sourced material causing off-odors or unwelcome color tones when they start their development runs. We take those lessons to heart and invest in continuous improvement so that each drum we send stands behind its number.
This compound’s full chemical description is long—3-Nitro-4-Hydroxyethylaminophenol, frequently called 3-nitro-4-(2-hydroxyethylamino)phenol by chemists. The CAS number guides regulatory compliance checks and helps customers trace the source. In our warehouse, we refer to it by production lot numbers, each one logged with synthesis dates, tank usage, and testing histories.
From hands-on runs, we know the main challenges stem from temperature control during nitration and careful pH adjustment before extraction. Reaction speed directly affects color intensity and crystal form. We learned that shaving off even a few degrees Celsius on the jacket can swing the product from a sticky mass to a dry, manageable powder. Cleaning is crucial—cross-contamination from earlier lots ruins purity, so our team uses dedicated glass-lined reactors just for phenolic dyes. This step may sound minor, but it saves hours during final analysis and keeps long-term clients happy.
Specifically, our current process targets:
We field many questions about appearance. Slight color variations naturally occur due to small changes in raw naphthol lots or even weather shifts mid-batch. Customers rely on us to alert them if a lot swings outside the typical shade spectrum. This proactive communication avoids unpleasant surprises when they scale up their own production.
The principal use for this molecule lies in permanent hair dye formulas. As manufacturers, we see firsthand the demand spikes ahead of new product launches and the rush to qualify every new lot ahead of brand rollouts. Customers rely on our reproducibility for oxidative dye applications where the interaction between this compound and coupler bases sets the tonal characteristics, covering grays and achieving vibrant, lasting colors. A lot of what we do revolves around tuning solubility and buffering to fit into demanding process lines—sometimes involving rapid high-shear mixing, sometimes requiring gentle hand-stirring and long settling times.
On the plant floor, speed and reliability rule the day. Our consistent specs let formulators lock in process parameters instead of recalibrating every week. One batch might end up in a rich chestnut brown; another, as part of a delicate cool blonde. We occasionally handle requests for customized lots with altered crystal forms or pre-mixed blends. By staying close to our users, we can anticipate what will help them reach their own quality benchmarks.
Competitors sometimes focus solely on price, but our clients pay attention to traceability and quality backup. We’ve seen formulas fail because of variable moisture, unexpected side-reactants, or insufficient washing during isolation. The small details—extra-washed batches, in-house analytical fingerprinting, and flexible packaging—mean our buyers face fewer production stoppages and customer complaints. Some new users come to us following bad experience with uneven dissolving speed or product settling. By tracing each problem back through supply chain, we know how crucial lot history and storage discipline prove for avoiding future issues.
We have also noticed that certain suppliers cut corners during final drying. That shortcut may work in the short run, but it often results in micro-impurities that only show up months later, especially in higher-output cosmetic lines. Our routine includes extended vacuum drying and careful nitrogen packaging, drawn from repeated stability studies. This added effort is not always obvious at first glance but becomes clear as batches age and color performance holds steady during storage.
We remember early years grappling with raw material inconsistency. Precipitate formed unpredictably, giving headaches for both lab analysts and end users. To address this, we developed raw material intake checks—every barrel, drum, or bag undergoes NMR and spectral scan before it hits our reactors. When a material batch even slightly misses purity targets or shows unusual spectrum peaks, we reject it outright. Not every plant can make this call with tight lead times, but we believe it keeps our downstream numbers strong and saves headaches for dye developers.
Listening to customer stories fueled several adjustments over the years. One major improvement stemmed from a European partner who noticed tiny specks appearing in final dissolutions—a sign of incomplete washing steps on our end. We revised our protocol, doubling the wash cycles and implementing a two-stage filtration, which added a minor cost burden but nearly eliminated complaints. Another time, a customer needed a different particle size to run cleanly in a new high-speed mixing line. We collaborated, running pilot lots until the right range emerged, supported by in-line particle counters rather than static sieves.
We don’t see product development as a finished task. Each year, we evaluate analytical techniques—switching from thin-layer to HPLC, adding capillary electrophoresis, and bringing in outside trace metal checks to catch what routine labs sometimes miss. By staying nimble in our QC approach, we not only secure existing client trust but also keep new research teams interested.
As a manufacturer, we must remain vigilant about safety and regulatory compliance. Handling nitro and amino intermediates asks for serious attention to both worker safety and downstream consumer concerns. Our knowledge grew from the inside out—training staff, building proper ventilation, and investing in both equipment and certification. Final product testing reflects compliance protocols from the EU, US, and certain APAC authorities. This stops at more than a paperwork exercise; regulators occasionally show up with spot audits, requiring us to demonstrate chain-of-custody and impurity traceability.
Over the last decade, consumer concerns over allergens, impurities, and environmental fate pushed us to lower byproduct loads further. Some traditional drying agents went out of the protocol, replaced by more benign options. We pay attention to discharge limits, support partners with data for environmental dossiers, and adopt renewable raw materials where possible. We track stricter regulatory climate as an opportunity to prove transparency and quality, not just a bureaucratic burden.
Warehouse staff remember shortages and delivery interruptions from early pandemic months. It drove home the importance of stable sourcing and local alternatives for solvents and precursors. Today, we qualify multiple suppliers and stagger inbound schedules. Every lot we ship includes a complete COA, along with safety, shelf-life, and material flow data—not just to satisfy compliance but to help users keep their records tight.
Packing options adapted over years—heavy-duty fiber drums for bulk, vacuum-sealed pouches for high-sensitivity users. Adjustments came about after clients complained about clumping from condensate when products traveled by sea in humid months. Nitrogen-purged liners and desiccant packs became standard on export shipments, based not on theory but from post-delivery complaint records. We’ve also stepped up to offer smaller pack sizes for lab development groups wanting to experiment, keeping inventory manageable for smaller companies.
Consistency relies on human attention—no in-line sensor fully replaces an experienced plant hand checking for off-odors or unexpected clumping. Even with digital batch tracking, hands-on routine checks catch more issues before they end up on customer lines. We constantly revisit mixing times, solvent recovery, and filtration speed. Getting these factors right does not just improve yield; it reduces impurity risk and keeps our environmental impact lower. Every kilogram of product reworked or disposed of is lost value and potential negative impact on both the bottom line and the planet.
Periodic reviews of waste stream composition led us to install advanced scrubbers and tailor our solvent recovery units. Early in our process history, we underestimated exhaust loads, leading to near-miss environmental compliance issues. Investments in closed-loop systems, combined with operator training, reduced both emissions and unplanned shutdowns. We aim for a process where every liter of reagent leaves as finished product or reusable input, not as problem waste.
Our clients range from startups in hair care to multinational giants. Working closely with research teams, we support small pilot projects, offering technical support and rapid feedback. Director-level chemists sometimes call us directly to talk through formulation sticking points, as they know our team works from a real production base, not just a catalog or specification sheet.
Several projects over the last few years moved toward greener, lower-impact processes. Switching to water-recycled syntheses and eliminating certain dangerous intermediates improved both our workplace safety indicators and downstream acceptability among eco-conscious brands. We welcome requests for modified grades, such as low-odor or custom-particle variants, knowing that flexibility is valued more than theoretical minimum spec level.
The demand curve for 3-Nitro-4-Hydroxyethylaminophenol continues to shift with trends in personal care, new hair dye fashion, and rising global populations. As manufacturers, the goal remains to provide not just high-quality intermediate but a real support system for every customer working to bring safer, reliable, and innovative products to market. Our continuous investment in technical upgrades, listening channels, and people—both in the plant and in customer service—puts us in a position to adapt and lead, not just follow changing industry norms.
Our long experience with 3-Nitro-4-Hydroxyethylaminophenol goes beyond simply filling orders. Each kilo leaving our doors carries the weight of thousands of production hours, real-world troubleshooting, and an ongoing pledge to reliability, transparency, and partnership. We know that solid performance in the dye sector requires more than meeting a benchmark purity. It calls for learning from clients, anticipating needs, and dedicating engineering and technical resources toward continuous, measurable improvement. That is how we measure our success and the reason we remain trusted by hair dye manufacturers and formulators across the industry.
