|
HS Code |
282180 |
| Chemical Name | 3-Iodophenol |
| Cas Number | 591-56-4 |
| Molecular Formula | C6H5IO |
| Molecular Weight | 219.01 g/mol |
| Appearance | White to light yellow crystalline powder |
| Melting Point | 84-88 °C |
| Boiling Point | 210 °C (lit.) |
| Density | 2.09 g/cm³ |
| Solubility In Water | Slightly soluble |
| Purity | Typically ≥98% |
As an accredited 3-Iodophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | Amber glass bottle, tightly sealed with a screw cap, labeled "3-Iodophenol, 25g," featuring hazard warnings and CAS number. |
| Shipping | 3-Iodophenol is typically shipped in tightly sealed, chemically resistant containers to prevent contamination and moisture absorption. It is handled as a hazardous material, requiring appropriate labeling and documentation. Transport follows regulations for toxic and environmentally hazardous substances, ensuring safety through secondary containment and temperature control if necessary. |
| Storage | 3-Iodophenol should be stored in a tightly sealed container, protected from light and moisture. Keep it in a cool, dry, and well-ventilated area, away from sources of ignition, strong oxidizing agents, and incompatible materials. Ensure proper labeling, and avoid exposure to heat. Store in accordance with local regulations and safety protocols for hazardous chemicals. |
Competitive 3-Iodophenol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615380400285 or mail to sales2@liwei-chem.com.
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Tel: +8615380400285
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Years on the factory floor and at the research bench shape the way we make each batch of 3-Iodophenol. Bringing consistent color, particle size, and purity to every drum is not only a demonstration of chemistry—it’s a responsibility to the chemists, formulators, and manufacturers who rely on our supply. This compound isn’t just another arrow in the quiver. Its value turns on reliability, and a reliable supply chain comes from expertise earned through years of focus, not shortcuts.
The daily grind of chemical manufacturing puts claims to the test. Over time, we’ve learned no two batches of raw material behave the same. Our approach to 3-Iodophenol starts with careful selection of phenol and iodine inputs, handled with safe containment and a steady hand during synthesis to minimize off-white impurities and prevent trace halogens running high. Instead of seeking only high yields, we measure ourselves by batch-to-batch tightness on purity and product consistency.
We deliver 3-Iodophenol under the model designation 3IP-98, with assays verified above 98%. Each kilo crystallizes in a state that reduces dusting but remains easy to dissolve, a detail we nailed down after years of feedback from downstream users who lost time correcting for clumped or overly fine powder. We watch for residual solvents, knowing that every percent point over spec could throw off a delicate step in your process.
Our own experience tells us not all building blocks work the same in the hands of a synthetic chemist. 3-Iodophenol stands out in the toolbox for one reason: the placement of the iodine atom provides a unique lever for cross-coupling, halogen-exchange, and aromatic substitution. This gives it an edge in pharmaceutical intermediates, dye synthesis, and specialty material development where less reactive halides like bromo- or chloro-phenols fall short.
Some of the most innovative molecules our clients create depend on the fast, clean bond-forming properties of iodine at the meta-position. 3-Iodophenol’s reactivity can streamline Sonogashira coupling, Buchwald-Hartwig aminations, and Suzuki reactions, unlocking access to active pharmaceutical ingredients, advanced pigments, and electronic materials. For teams scaling up new ideas from milligram trials to kilogram runs, every percentage point of unwanted byproduct matters. That’s why our process aims to keep organic and inorganic contaminants below actionable thresholds, not just for label compliance but to avoid costly, time-consuming rework.
Purity on paper means nothing without proof at scale. We specify our 3IP-98 at not less than 98% by GC/MS, and shipments can trend higher when isolation allows. From feedback across lab, pilot, and production settings, we know how even a fractional point below spec can skew chromatograms, cause color changes, or slow key reactions.
Water and related volatiles receive the same attention. Excess moisture doesn't merely change weight—trace water picks up in downstream HPLC traces or sends reaction yields off target. Instead of waiting for downstream complaints, our in-line moisture control and nitrogen blanketing minimize these headaches in advance. Packing in pre-weighed, inert-lined bags avoids extra handling and risk of moisture uptake, which often gets overlooked at the dock or during warehouse turnover.
Impurities like free phenol, diiodophenols, and unreacted iodine top the list of troublemakers. Each can foul catalysts, poison polymerizations, or push analytical readings out of bounds. Rather than chase these with last-minute purification, our prep and distillation train focuses upstream, where flaw prevention works better than correction after the fact. We take pride in delivering not only a tight main peak on the chromatogram but a low baseline and predictable impurity fingerprint. Chemical process engineers trust this difference during scale-up or validation, where uncertainty turns into real cost.
Easy sourcing does not substitute for dependable performance. Some might reach for 2- or 4-iodophenol or their bromo- or chloro- counterparts, but years of synthetic trials confirm: not every halide or ring position works the same.
3-Iodophenol’s meta-iodo position opens up routes barred to its ortho and para relatives. Its increased steric freedom compared to 2-iodophenol enables a cleaner, more predictable coupling in electronic and pharmaceutical intermediates. The 4-isomer sometimes offers easier handling but lacks the same selectivity or reaction rates in many palladium-catalyzed couplings. With multistep syntheses, switching to a less reactive halogen like bromo often means higher activation energies and increased waste in workups—costs that increase with scale.
Cheap imports often fall short on actual content or introduce contamination. Time and again, we see phenolic odor, excessive color, or residue in samples from traders. Some cut corners on raw phenol grade or neglect purification, betting most customers won’t spot trace halides until days into project delays. Our own controls start with reagent grade inputs, followed by staged crystallizations and drying cycles. Every batch then undergoes in-house and third-party analysis before release, giving end users data they can trust, not assumptions on a certificate.
Pharmaceutical discovery teams rely on our 3-Iodophenol for key coupling steps, often feeding into aromatic amines and ethers where consistent meta-iodination cannot be compromised. Their lead times might not allow for pre-treatment, so clean, ready-to-work material matters most. Pigment and dye manufacturers extract value from the selectivity: lower byproduct formation leads to easier purification and longer filter life.
Electronic chemical companies tell us their yields improve when using our 3IP-98 for fabricating advanced functional materials. We’ve seen their quality numbers track closely with our delivered quality as devices move from pilot to pre-production. Each year, tighter device specs reward those who pick reliable chemical sources over just-in-time imports.
From our side, we monitor process feedback closely, taking note when customers report changes in solubility, melting point, or color. By mapping performance back to each production run, we’ve discovered subtle effects of season, storage, and transport. This tight feedback loop lets us tweak process parameters long before problems become entrenched.
We have seen small handling lapses shorten shelf life or degrade product, especially when packs are opened and left exposed. Poly-lined containers reduce the risk of water sorption, and desiccants are sometimes requested for large-scale users in humid climates. As oxidation from air exposure at high temperatures can skew both color and purity, we package only after thorough cooling and purge with inert gas. This step matters most for bulk shipments sitting in transit or in warehouse storage longer than a few weeks.
A little up-front caution avoids trouble. We encourage end users to sample and reseal tightly, using unopened bags for critical syntheses. These practical habits, born from our own studies and from troubleshooting customer incidents, prevent downtime and help preserve the as-delivered profile of every batch.
Our partnerships with research-driven pharma companies and chemical startups have taught us to respond nimbly. Sometimes innovation demands not only the standard 3IP-98 grade but tighter particle size or alternative solvents for blending. By running small, custom batches, we help project teams avoid delays, scaling from gram samples to multi-ton runs with real process feedback at every step.
For ongoing projects where byproduct control or specific crystallinity matter, we can push drying steps or filtering regimes a step further—always weighing customer feedback against overall cycle time and production cost. Unlike traders, we control what goes into the reactor and what comes out of the final centrifuge. Through this hands-on involvement, problems don’t just get reported; they get solved on the next run, often before the end user spots a deviation.
Working with iodine and phenolic raw materials requires more than chemical skill; factory and community safety comes first. Our containment and ventilation upgrades over the years stem directly from real-world incidents—leaks, equipment wear, and accidental releases. Each lesson raised our standard for operator PPE, spill control, and waste capture.
On the environmental side, we’ve moved away from older, volatile organic solvent systems wherever possible, switching over to less hazardous alternatives based on operator input and waste minimization studies. Regular reviews of wastewater and air emissions take place, beyond what regulators or external auditors require. This focus keeps hazards under control and lets us lead on responsible manufacturing rather than chase minimums set by regulatory frameworks.
Years of production have shown that shortcuts in safety create nothing but long-term risk—for us and our customers down the chain. Giving our staff a voice on the shop floor and fostering a no-blame approach to incident reporting bring issues forward early while solutions are still easy and inexpensive.
Nobody knows a process better than the crew who keep it running through night shifts, equipment hiccups, and unexpected changes in raw material quality. We treat their experience as our R&D advantage. Over the years, line operators picked up subtle signs of early crystallization or uneven temperature changes during key steps of 3-Iodophenol synthesis. This awareness translates directly to fewer off-spec batches and faster troubleshooting.
New hires spend weeks shadowing experienced staff, learning what a normal reaction looks and smells like—and getting a grounded sense of what deviations mean. We’ve installed in-line monitoring not because automation replaces experience but because tools work best in experienced hands. Continuous review of yield, purity, and impurity patterns lets us push for incremental improvements while still meeting day-to-day delivery demands.
Every efficiency gains meaning only when it brings greater batch reliability or environmental safety. We report on these improvements, sharing real numbers and root-cause analysis with our long-term partners. Updates come not as advertisements but as working proof that we value ongoing trust over transactional sales.
Beyond shipping verified product, we answer technical questions with depth. Analytical chemists might call with questions about the suitability of 3-Iodophenol for a specific coupling or purification protocol, and we give clear answers based on our own process data. Instead of quoting standard references, we use real failure modes and production findings straight from our logs.
Unusual solids, color change, or residue in customer reactors signal real concerns, not just “process variation.” Our support responds with counter-samples, analytical clarifications, and, where possible, small-lot customization to restore confidence and minimize downtime. Our ability to trace every pack back to its raw materials, synthesis lot, and QC data means technical answers are never far from the factory floor. Unlike distant traders, we stand behind what we make, with accountability that runs from the first drum to the last.
We’ve tested 3-Iodophenol across multiple seasons, warehouse conditions, and storage times. Our recommended shelf life comes from evidence, not guesswork. Opened packs in humid air experience more rapid color shifts, so we reinforce the use of properly sealed containers, silica desiccants, and storage away from direct sunlight. Most users consuming material within a few months rarely see a difference, but planning for yearlong supply or slow-moving R&D programs? We provide detailed stability data and help clients develop custom storage protocols to match.
Bulk powder in open drums is a recipe for trouble. If a customer’s process can’t avoid frequent opening, we can offer subdivided packaging or inert-atmosphere shipment to keep degradation at bay. We monitor returns and complaints, sifting for patterns that expose new storage vulnerabilities before routine handling turns into product loss or wasted effort.
Ownership of each synthesis, purification, and packaging stage gives us flexibility no third-party supply chain can match. Facing sudden changes in global logistics or regulatory standards, we can reroute batches, adjust specifications, or accelerate lot releases to keep production lines running. Feedback from partners in pharma, pigments, and electronics circles often shapes our next round of upgrades.
Longstanding relationships with key raw material suppliers help insulate us from supply volatility. When disruptions do occur, we prefer slowing down to guarantee purity and reliability rather than diluting standards for the sake of speed. Our volume flexibility—scaling from pilot lots to bulk—lets emerging innovators work through the inevitable scale up issues without the uncertainty that comes with untested sources or unpredictable imports.
Year after year, customers come back not for the cheapest 3-iodophenol, but for a partner who stands behind every batch and adapts to the evolving needs of those at the cutting edge of chemistry. Every process improvement, new application discovery, and stability insight starts with listening: to our own process, to customer feedback, and to the lessons each run delivers.
From tiny benchtop studies to multi-ton batch orders, our commitment remains the same: dependable 3-Iodophenol, produced by those who know their chemistry—informed by years of running, troubleshooting, and continually driving for the better product that end users deserve. The proof, as always, is in the product, and in the relationships built one shipment at a time.
