Anhui Liwei Chemical Co., Limited
Products

3-Carboxy-4-Nitrophenol


    • Product Name 3-Carboxy-4-Nitrophenol
    • Alias 3-Carboxy-4-nitrobenzoic acid
    • Einecs 242-734-6
    • Mininmum Order 1 g
    • Factory Site Lingwu, Yinchuan, Ningxia, China
    • Price Inquiry sales2@liwei-chem.com
    • Manufacturer Anhui Liwei Chemical Co., Limited
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    660547

    Iupac Name 3-carboxy-4-nitrophenol
    Molecular Formula C7H5NO5
    Molecular Weight 183.12 g/mol
    Cas Number 619-73-4
    Appearance Yellow crystalline solid
    Melting Point 192-194°C
    Solubility In Water Slightly soluble
    Boiling Point Decomposes before boiling
    Density 1.67 g/cm³ (approximate)
    Pka 6.7 (phenol group)
    Smiles C1=CC(=C(C=C1O)C(=O)O)[N+](=O)[O-]
    Pubchem Cid 20108
    Synonyms 4-nitro-meta-hydroxybenzoic acid
    Hazard Statements May cause irritation to skin, eyes, and respiratory system

    As an accredited 3-Carboxy-4-Nitrophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing A 25-gram amber glass bottle labeled "3-Carboxy-4-Nitrophenol," featuring hazard symbols and a tightly sealed screw cap for safety.
    Shipping 3-Carboxy-4-nitrophenol is shipped in tightly sealed containers, protected from moisture and light. It is classified as a hazardous chemical, requiring appropriate labeling and documentation. Transport must comply with relevant regulations, including handling instructions for corrosive and toxic substances, ensuring employee safety and environmental protection throughout transit.
    Storage Store 3-Carboxy-4-Nitrophenol in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances such as strong oxidizers and bases. Protect from moisture, heat, and direct sunlight. Use appropriate chemical storage cabinets for acids. Label the container clearly and restrict access to trained personnel. Wear suitable personal protective equipment when handling.
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    Competitive 3-Carboxy-4-Nitrophenol prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615380400285 or mail to sales2@liwei-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615380400285

    Email: sales2@liwei-chem.com

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    Certification & Compliance
    More Introduction

    Introducing 3-Carboxy-4-Nitrophenol: A Manufacturer’s Perspective on Performance and Value

    Understanding the Character of 3-Carboxy-4-Nitrophenol

    Packing years of chemical manufacturing experience behind every batch, we approach 3-Carboxy-4-Nitrophenol from the ground up. The product comes as a vibrant yellow crystalline solid. Its chemical structure shows a phenolic core with a nitro group positioned at the 4-position and a carboxyl group at the 3-position. Both of these functional groups impact its reactivity and set this molecule apart in the world of fine chemicals. The CAS number linked to this compound identifies it for traceability—important throughout the supply chain—and those needing high standards in research and industry.

    Working with this compound differs from handling basic phenols or bench-standard benzoic acids. The nitro and carboxyl motifs bring a combination of electron-withdrawing effects and site-selectivity that expands the chemistry toolbox. The melting point reflects the molecule’s stability. Purity impacts downstream reactions, especially in syntheses where sensitive intermediates do not tolerate contaminants. Every production run receives full analytical testing by UV, IR, and HPLC, emphasizing reliability batch after batch.

    Wide-Ranging Applications Reflecting on Real Needs

    We see interest in 3-Carboxy-4-Nitrophenol from several corners: specialty pigment manufacturing, pharmaceutical intermediates, dye chemistry, analytical reagent suppliers, and polymer modification. Talking with chemists in these sectors, the demand arises from the nuanced electron balance in this molecule. The nitro group pushes electron density away, while the carboxyl holds its own acidic identity, boosting usefulness in pH-sensitive assays, complexation studies, and as a precursor for coupling reactions. The color—intense yellow—suits applications where robust and stable chromophores matter.

    Some customers use this compound for diagnostic kits, taking advantage of its predictable reactivity. Others use it for azo dye coupling. We have also supported research on enzyme inhibitors, where this phenolic structure serves as a starting point. Using analytical data, teams can identify how minor impurities in incoming 3-Carboxy-4-Nitrophenol influence pathways or solubility, helping chemists optimize for yield or shelf life. Those in polymer chemistry tell us that the carboxylate group offers a ready handle for grafting or functionalization, usually under mild conditions.

    Distinguishing Features Versus Similar Aromatic Compounds

    Comparing 3-Carboxy-4-Nitrophenol with 4-nitrophenol or simple benzoic acids, differences in solubility, reactivity, and color fastness stand out clearly. Mono-substituted phenols generally lack the acid functionality and do not offer the same hydrogen bonding capacity or participate in salt formation so readily. With the dual substituent system, our product carries potential for greater water solubility, denser color expression, and more nuanced pKa behavior. This opens routes for controlled release studies or sophisticated lab analyses.

    The ortho relationship between carboxyl and nitro groups matters in synthetic planning. Reagents behave differently on this backbone compared to meta- or para-substituted analogs. From our own scale-up, we notice shifts in crystallization profiles and solvation characteristics, requiring tight control over solvent composition and cooling rates. In production, the dual substitution pattern pushes us to develop purification protocols that address not only the target but also closely related isomers—often a stumbling block in laboratory bench synthesis that we can smooth out by investing in better chromatography and solvent recapture.

    Supporting Responsible Innovation

    Through years of manufacturing, the focus lies not only on the chemistry but also on long-term performance in customer applications—reliability on repeated orders, transparency in specification, and adjustments based on operational feedback. Our efforts in quality assurance provide clarity before a drum leaves our site. Test data travels with shipments. Raw material sourcing supports regulatory scrutiny so customers have backing if questions arise around trace metals, process solvents, or environmental footprint. This attention to detail preserves reputation both for us and those formulating our intermediates into end-use products.

    A key point that practical chemists often highlight: the reduction and derivatization chemistry of 3-Carboxy-4-Nitrophenol yields intermediates that fit securely into multi-step synthetic schemes. Knowing how side reactions proceed across various pH, temperature, and mixing conditions shapes how we present technical support. More than once, we have helped scale up batch sizes or introduced formulations with higher water solubility or improved filterability. These are changes grounded in what actually happens in the reactor or filter press—not just what looks fine on paper.

    Production Lessons and Process Insight

    Manufacturing this compound reveals plenty about aromatic substitution, solvent selection, and workup. It becomes easy to spot where theoretical routes trade off against operational realities: some older literature suggests routes that risk explosive intermediates or unmanageable waste streams. In scaling up, staff prioritize safe nitration and controlled carboxylation, then build routine checkpoints for analytical purity. Our finished product avoids the resinous or tarry byproducts present in less-refined offerings—something we saw in samples purchased for process benchmarking. Investing in better glassware, modern catalysts, and robust ventilation has paid off with safer conditions and more consistent results.

    Every few months, feedback from end users comes through: “A little less insoluble content than the competition” or “Storage at room temperature keeps batch stability high.” Such details matter. Our own storage studies, looking at ambient, refrigerated, and high-humidity conditions, guide packaging and inventory advice. Rather than oversell shelf life, we prefer giving facts drawn from deliberate test cycles. This transparency fits with a trend we notice in customer requests—more often now focused on supply chain traceability, documentation, and sustainability scores, alongside price and performance.

    Improving Sustainability in Production and Downstream Use

    Today’s markets expect more than just chemical content. Responsible sourcing of nitration agents and carboxylate precursors forms one foundation. Much of the water and solvents used in each campaign find their way back to recovery tanks. High-yield routes minimize both raw material consumption and waste disposal. Data on process emissions and recycling rates often feature in customer audits. Rather than viewing these as hurdles, we treat environmental metrics as integral to the day-to-day operation—a point of pride for both our manufacturing and technical teams.

    Dye houses and pharmaceutical labs evaluating 3-Carboxy-4-Nitrophenol increasingly factor in not just molecular purity, but also the energy and water footprint. In response, we have shifted towards less energy-intensive purification. Crystallization and filtration, monitored by process analytical technology, deliver more consistent lots and less off-spec material to manage. Some customers ask for lifecycle assessments. These honest conversations, bringing to light both strengths and ongoing challenges, are part of supporting the full value chain. The result is a product that performs for chemists, leaves a lighter environmental mark, and informs future improvements.

    Fitting 3-Carboxy-4-Nitrophenol into Current Industry Trends

    Science keeps moving. Chromophore science, pharmaceuticals, and advanced material development increasingly demand specialty aromatics. Some end-uses, like in color-fast stable dyes, push for better solubility or resistance to degradation in demanding applications. In pharmaceutical research, the dual functional handles drive innovation in pro-drugs, enzyme inhibitors, and imaging agents. Process engineers consider not just technical properties, but also reliability of supply, consistency of melting or crystallization, and the expected behavior of each drum or bag through their own quality checks.

    Feedback from the bench often makes its way back to our team: “That batch finished a color reaction faster,” or “Solid dissolved more cleanly in my buffer than another supplier’s.” This encourages us to keep refining our particle sizing, analytical controls, and packaging formats. Unexplained batch-to-batch variation can disrupt timelines, especially when running parallel syntheses for screening or regulatory filing. We avoid the noise that comes from outsourcing or shifting between contract producers by keeping everything under one roof: reaction, purification, packing, and documentation.

    Long-Term Perspective on Impact, Quality, and Service

    Supplying 3-Carboxy-4-Nitrophenol is not about chasing lowest cost at the expense of safety, transparency, or performance. The real work involves listening to customer challenges, watching for new regulatory changes, and building stronger ties between the process engineers and bench chemists at either end of the supply chain. Each kilogram shipped reflects careful planning from raw material purchasing to QC endorsement—and probably a few hard-won lessons learned when novel applications call for tweaks in crystal habit, grain size, or impurity control.

    The human element remains central: experienced technicians, quality assurance staff with deep knowledge, and logistics teams who understand the quirks that can arise with specialty chemicals. Returns, shelf life requests, or questions about handling in specific reactors store chemical know-how across the company and reinforce a cycle of shared problem-solving. We keep track of performance data and listen to feedback, aiming to build relationships that last across product cycles, regulatory updates, or expansion into new regions.

    Supply reliability builds on history. Many customers have relied on the compound for years, citing not only consistent properties, but also confidence in repeatable results across manufacturing lots. If changes in raw material supply occur, adjustment in process or blend is communicated—not left to surprise. Documented analytical results, retained samples, and thoughtful change management are standard operating procedures. With growing scrutiny on all nodes of the chemical value chain, adopting these practices carries weight: regulatory authorities often audit not just paperwork, but the lived reality and supplier relationships.

    Growing with the Evolving Chemistry Market

    Market demand does not stay static. Requests have shifted, asking for larger lots, tailored packaging, or greener synthesis routes. Researchers tackling new synthetic challenges often send word about conditions that work better, solvents that minimize waste, or temperature windows that avoid unwanted side-products. In response, we adjust—not just because it meets a specification, but because it supports smoother downstream operations and reduces surprises for anyone using the compound.

    Keeping 3-Carboxy-4-Nitrophenol reliably available means not only maintaining production stocks, but also building resilience into raw material procurement and process scheduling. Geopolitical factors, logistics disruptions, or upstream feedstock issues come up and are managed through robust inventory and alternate sourcing. During challenges, open communication ensures customers have options and advanced warnings—preserving timelines for those racing to meet regulatory filings or research deadlines.

    Product Experience Built from the Floor Up

    The plant floor shapes every bottle, drum, or tote. Interactive training ensures staff know the expectations, safety procedures, and test methods inside out. Any process improvement cycles back, whether it’s a faster crystallization step or a safer venting method. The culture of learning helps keep consistency high, and continuous investments into instrumentation and staff well-being pay dividends in lower error rates and higher product satisfaction. Building on that, familiarity with the quirks of 3-Carboxy-4-Nitrophenol’s process chemistry—such as controlling exotherms or avoiding runaway side reactions—provides confidence batch after batch.

    Customer visits, plant audits, or joint troubleshooting sessions regularly lead to step changes in quality or logistics. Packaging formats shift in response to real-world feedback—more moisture-resistant liners for humid climates, tamper-evident closures, or size options tuned to minimize waste and handling time. Each improvement is tested against both internal standards and customer feedback loops. This responsive approach closes the distance between manufacturer and user, driving trust and positive performance outcomes.

    How 3-Carboxy-4-Nitrophenol Makes a Difference

    The marketplace offers many yellow phenolic compounds. The subtle balance of carboxy and nitro groups in this product creates new reactivity avenues, opens up selectivity in coupling steps, and offers flexibility for formulation specialists. Customers put faith in ease of dissolution, clarity of color, or well-documented acid/base behavior. Elimination of marginally soluble tars or unwanted byproducts results in faster filtration, less clean-up, and cleaner reaction profiles during scale-up experiments. With stakes running high in pharmaceutical discovery or pigment innovation, every bit of extra care on the manufacturer’s end passes directly to the end user as both savings and confidence.

    Application support does not end once the product is shipped. New regulatory requirements, customer-driven audits, and shifting analytical standards create a dynamic context. Every time a technical query appears—about a minor spectral impurity, a handling question, or documentation for cross-border transport—response draws on archived runs, tested protocols, and the practical experience of people who have run the process before. These established records and real-life knowledge inform recommendations, making sure customers don’t hit roadblocks as they move to pilot or launch scale.

    Transparency, Documentation, and the Value of Real Experience

    One factor standing out today: transparency. Whether it’s data speed, completeness of analysis, or willingness to supply secondary reference standards, users expect the full picture. Our standard shipments come with full COA packets, method sheets, and shipping documentation matching traceability demands from regulators and auditors. Experience building batches of 3-Carboxy-4-Nitrophenol for decades means past deviations, process changes, or lessons learned are carefully tracked. Customers access this living body of know-how, saving time and risk in their own projects.

    On more than one occasion, a project manager has asked for support navigating application-specific requirements: adjusting for local storage regulations, reviewing exposure data, or coordinating multi-site shipment deliveries. Rather than refer to generic distributors or outsource responsibility, the answer comes from those who actually run the plant, manage the logistics, and build the technical foundation. This solidarity and accountability match current trends in pharmaceutical and fine chemical procurement—where price matters, but so does the supplier’s capacity to support the entire product lifecycle.

    Steadfast in Quality, Ready for Change

    Working directly at the heart of chemical manufacturing gives us insights that extend beyond the molecule. Batch data becomes the backbone of reliability. Production staff become not only labor, but knowledge keepers and innovators. For a molecule as specialized as 3-Carboxy-4-Nitrophenol, no substitute exists for consistency, practical technical support, and shared commitment to safe, efficient, and sustainable performance. As industry needs shift—towards ever-purer ingredients, reduced contaminants, greener synthesis, or better global access—the experience and resilience built into every product unit remain the real differentiator.