|
HS Code |
526074 |
| Cas Number | 1013-21-6 |
| Molecular Formula | C6H7NS |
| Molecular Weight | 125.19 g/mol |
| Appearance | Light brown to yellow solid |
| Melting Point | 33-36°C |
| Boiling Point | 251°C |
| Density | 1.22 g/cm3 |
| Solubility In Water | Slightly soluble |
| Flash Point | 110°C |
| Purity | Typically ≥98% |
| Structure | A benzene ring substituted with an amino group (-NH2) at position 3 and a thiol group (-SH) at position 1 |
| Iupac Name | 3-aminobenzenethiol |
| Storage Temperature | Store at 2-8°C |
| Smiles | C1=CC(=CC(=C1)S)N |
As an accredited 3-Aminothiophenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 3-Aminothiophenol is packaged in a 25-gram amber glass bottle with a tightly sealed cap and hazard labeling for safe storage. |
| Shipping | 3-Aminothiophenol should be shipped in tightly sealed containers made of compatible materials, away from strong oxidizers and moisture. Store and transport at room temperature, following all relevant hazardous materials regulations. Ensure proper labeling, safety documentation, and secondary containment to prevent leaks or spills during transit. Handle with appropriate protective equipment. |
| Storage | 3-Aminothiophenol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area away from sources of ignition, heat, and direct sunlight. It should be kept away from incompatible substances such as strong oxidizing agents and acids. Proper labelling and secondary containment are recommended to prevent leaks and spills. Store under inert atmosphere if possible. |
Competitive 3-Aminothiophenol prices that fit your budget—flexible terms and customized quotes for every order.
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For many years, we have operated at ground level in chemical manufacturing, responsible for each reaction, purification, and packing run of 3-Aminothiophenol. We pay attention to each production batch from startup to final QC inspection. Watching the input material transform and handling each kilogram brings a kind of respect for every subsequent stage. From these long stretches on the factory floor, I've come to appreciate both the practical challenges and the vital potential of 3-Aminothiophenol—especially when differentiation and traceability matter to customers in pharmaceuticals, electronics, and specialty materials.
Each batch of 3-Aminothiophenol that leaves our facility reflects a track record anchored in routine process optimization, hands-on experience, and strict adherence to validated methods. Our team believes in transparency—not only internally for quality control, but also externally, as the users who choose chemicals from us often work in critical processes where reliability is everything.
3-Aminothiophenol, known chemically as 3-aminobenzenethiol or M-aminothiophenol, brings together an amine and a thiol functional group on a benzene ring. The actual product comes off our reactors as an off-white to pale yellow crystal, sometimes appearing slightly darker due to handling atmosphere or minor variances in temperature during drying. Its chemical formula is C6H7NS, and the molecular weight reads 125.19 g/mol. Purity generally reaches above 99%, verified with HPLC and melting point testing. We sample multiple times from each lot because experience has shown even a fraction of a percentage drop in purity will change the behavior downstream, especially in synthesizing fine chemicals or preparing high-grade intermediates for the electronics sector.
What sets 3-Aminothiophenol apart from other aminothiophenol isomers is the position of the amine and thiol groups—each affecting reactivity and compatibility in synthesis. This meta arrangement changes the electron density and directs the kinds of coupling or substitution reactions that take place, and as a manufacturer, these subtle changes are not abstract. If an end user substitutes the ortho or para analog, the resulting reaction can yield lower conversion rates or introduce side products that are hard to remove. Even the color or odor may shift—a frustrating discovery if discovered only after a large-scale reaction. When speaking with clients, we always clarify that the 3-position is crucial for building blocks in dye synthesis, pharmaceuticals, or specialized surface modifiers.
It’s one thing to read about a compound’s properties in textbooks. Producing it on a commercial scale introduces a different challenge. Handling the starting materials—often nitrothiophenols or related intermediates—demands extensive care, especially as some reagents pose hazards due to volatility or sensitivity to oxidation. Each time we set up a reduction or amination step, plant engineers walk the line, checking for leaks, monitoring temperature profiles, and ensuring that the agitation never lags. Often, we configure batch times and flows based on humidity levels, since water ingress may cause hydrolysis, introducing unwanted impurities in final 3-Aminothiophenol. Maintaining nitrogen or inert conditions during reaction and storage has proven essential for stability.
The importance of exacting purification can’t be overstated. Early in our production experience, we observed that failing to adequately separate side products—especially related isomers or disulfide byproducts from the thiol—caused headaches downstream. Simple crystallization or washing won’t do; we implemented fine-tuned column chromatography or multi-step solvent extractions, adding steps only after direct yield data justified the extra investment.
Packing represents another key stage. We switched to high-barrier containers and nitrogen flushing because atmospheric exposure accelerates discoloration and odor changes. Our practice keeps this sensitive intermediate in a much more stable state, minimizing waste and improving shelf-life compared to earlier packaging approaches. This benefits customers, as they spend less time adapting their own handling protocols or vetting each new batch.
3-Aminothiophenol regularly finds use in a handful of high-value corners of industry. In our collaborations with pharmaceutical teams, it’s often requested for the synthesis of certain APIs—especially in forming sulfur-containing heterocycles or as a coupling partner to introduce amino or thiol moieties in late-stage intermediates. The electronics and nanotechnology fields increasingly depend on 3-Aminothiophenol as a molecular linker in surface modification, providing chemically reactive points for antibody immobilization or for building self-assembled monolayers (SAMs) on gold or other metals.
We’ve noticed upticks in demand from specialty dye and pigment companies. The unique electronic characteristics of the meta isomer influence the chromophore formation, yielding different hues and stability compared to para- or ortho-analogs. In these applications, shelf stability and purity become critical: trace impurities will cause unwanted color shifts or degradation during formulation. As a manufacturer, we maintain direct contact with dye R&D teams, who tell us even minor discrepancies in odor or color signal a need for a more thorough batch investigation.
With growing emphasis on traceability, our internal tracking system logs every kilogram by batch and retains retention samples for at least two years. Confirming identity by NMR, IR, and HPLC gives us confidence—and when customers come back with analytical questions, we draw on that data to answer them directly. Many producers down the line in fine chemicals and materials science count on this detailed documentation.
Not every 3-Aminothiophenol on the market performs identically, even if labeled as 99% pure. As direct producers, we’ve run parallel trials using our material versus bulk-listed commodity imports. Our crystals dissolve more cleanly in common solvents, and stirring times drop when moving to scale-up processes. The reason, traced back, relates to both synthetic method and work-up: less byproduct means fewer filtration headaches and more predictable downstream reactivity.
During scale-ups in customers’ pilot plants, engineers routinely ask for consistency in physical form (grain size, flowability), low moisture content, and reliable packaging. Deviations—even minor—will disrupt automated feeders or dosing pumps. We adjust granule size ranges and dedicate equipment where justified by ongoing client feedback. Over time, our adaptation of the process has actually reduced total waste, both in our facility and in the final application.
We have also compared shelf-life experiments: Our sealed product stored at ambient conditions shows less color and odor change after twelve months than some competitive samples pulled from regional markets. This improvement comes directly from minimizing exposure to air and water vapor through packaging innovations and logistics investment—not simply from an abstract specification sheet.
Producing and handling 3-Aminothiophenol teaches respect for its properties. The compound’s sharp odor signals even a trace amount escaping into plant air. Teams wear appropriate PPE, including nitrile gloves, safety goggles, and respirators where indicated. Exposure to skin or mucous membranes causes irritation, and spills demand rapid attention to avoid persistent odors or corrosion to exposed surfaces. Regular fume hood checks and waste container monitoring help minimize risks.
On scale, incidents such as uncontrolled heating or accidental mixture with strong oxidizers have direct consequences. Training drills in our facility include quick evacuation for leaks and thermal events, not simply standardized “safety compliance.” Our MSDS and on-site emergency response options reflect real scenarios—the actual incidents, minor and rare, that have taught us where the bottlenecks lie.
Customers often ask about stability in finished products, where 3-Aminothiophenol enters into complex matrices or seeps into micro-volumes on circuit boards. In those cases, the meta arrangement is less prone to certain oxidation or polymerization pathways than its ortho or para relatives, but no production run should skip chemical stability testing over weeks or months. Our development chemists run accelerated age testing before we release for larger contracts.
Every restart in production highlights the importance of strict QC controls. We keep a real-time log on each reactor stage, pulling samples for colorimetric analysis and verifying functional group identity. Analytical infrastructure here includes NMR, FTIR, HPLC, as well as physical property testing like melting point and moisture content by Karl Fischer titration. These methods trace every anomaly, no matter how subtle.
Quality inspection doesn’t stop at release. We field customer inquiries, sometimes in real time, walking through batch records to trace any alleged issue. If a customer encounters an unexpected impurity or performance problem, we invite them to visit, observe our process, and collaborate on a solution. Many times, mutual technical review improves not only our product but their own process, shortening development times.
Early in our manufacturing expansion, we discovered a batch affected by unexpected atmospheric contamination. Identified by a faint yellowing of the crystals, this incident led us to uphaul our drying and packing line. Beyond updating materials, this drove new staff training and an internal requirement for double-checking all container sealing. Sharing these lessons with customers has gone far towards building real trust in our supplier relationship.
Regulatory pressure around handling and disposal of aromatic thiols and amines grows each year. Our direct engagement with compliance officers, inspectors, and environmental engineers means that issues like odor control, effluent treatment, and even loading dock cleaning move from theory to daily practice. We run closed-loop air handling with activated carbon scrubbers and prioritize solvent recovery on each distillation cycle. Water from production undergoes on-site neutralization and testing before discharge, as public concern over persistent amine species is real and justified.
Recent audits have driven us to document not only our direct emissions, but also the fate of packaging materials and downstream waste. We adapt internal labeling and sorting protocols so our containers do not add to the local refuse stream, working with recyclers whenever possible. These adjustments do not directly show up in a given batch’s analytics, but our clients—especially those in regulated industries—care as much about traceability and eco-footprint as about technical performance.
Adhering to emerging chemical control requirements for export markets brings yet another dimension. We closely monitor updated REACH, TSCA, and other chemical listings to guarantee no shipment encounters customs delays due to missing data or incomplete hazard labeling. Our technical team takes direct ownership—researching, documenting, and keeping communication lines open with both regulators and customers, so transitions go as smoothly as possible.
We see demand for higher-purity, functionally tuned 3-Aminothiophenol emerging from sectors pushing at the edge—semiconductors, advanced coatings, targeted drug conjugates. Requests come in for low-odor, ultra-low moisture, or stabilized variants for exacting synthesis. Our R&D group pursues process changes such as alternative reduction chemistries or continuous-flow conversion steps, evaluating not just yield or throughput but real-world reproducibility. We track each candidate process in pilot runs, making side-by-side comparisons to ensure gains do not trade off against other crucial characteristics—such as scalability or plant safety.
During these development phases, customer partnerships matter most. Fielding direct feedback, arranging joint investigations on trial batches, or customizing physical forms for a new synthesis route keeps both sides invested. Recent successful collaborations cut raw material costs and energy use by 20%, simultaneously reducing emission levels. These gains rarely appear overnight: they grow out of a shared willingness to analyze hard data and make targeted adjustments, not from generic improvement plans.
As a manufacturer, each new contract or development project reflects years—often decades—of trial, error, and cross-discipline conversation. Change and uncertainty will always shape the business, but our ground-level approach insists on tangible results: real product performance at the user’s bench or reactor, backed by diligent tracking and shared problem solving.
For any user seeking 3-Aminothiophenol, sourcing matters at least as much as purity or price on a datasheet. Distributors and global supply networks can introduce delays or rebranding, but manufacturing at the source offers an open channel for technical advice and traceability. We spend time explaining batch-to-batch histories and troubleshooting application issues with real data in hand. Direct feedback between the end user and our production or lab team shapes the next cycle of improvement—closing a loop that rarely exists when chemicals move only through sales intermediaries.
In every dialogue with a formulator or research group, our team values specific technical needs. Some request minimized odor and focused stability for sensitive surface treatments; others call for larger particle formats for blended feedstock. Sourcing direct enables these discussions, shifting production or packaging parameters as required, and making time for side-by-side process trials when unusual challenges arise.
Ultimately, 3-Aminothiophenol is not a generic commodity. Its performance, consistency, and overall value all trace back to genuine hands-on engagement by the producer. From raw material selection to validating test results to final packaging, the work is guided by cumulative know-how. This expertise is difficult to duplicate or substitute, forming the foundation for true reliability in every customer application—from pilot-scale R&D to full-scale manufacturing.
Current economic shifts and increasing scrutiny over chemical origins, purity, and sustainability add new complexity every year. Market volatility sometimes pushes buyers to seek out the lowest initial prices, with inevitable sacrifices in technical support or long-term consistency. Experience teaches us that direct engagement between producer and user delivers best-in-class solutions, lowers unexpected costs, and ensures adaptation when regulatory or performance demands intensify.
To keep pace with these expectations, our process focuses on adaptive planning. Each review of batch yield, purity data, and packaging condition prompts internal refinements immediately—not just annually. Troubleshooting is done in real time; trial collaborations are encouraged, not discouraged. As we continue to upgrade plant infrastructure and develop greener synthetic routes, the lessons from every batch, every shipment, are integrated by the same people who operate the reactors and manage QC release.
The promise of 3-Aminothiophenol rests on more than a chemical formula or a purity figure. In the hands of dedicated producers, refined through routine feedback and technical challenge, it becomes a reliable tool for problem solvers throughout the value chain—from research chemists developing the next API to engineers tuning microelectronic coatings. Our team remains committed to delivering this product with careful attention, honest communication, and an eye toward solutions, now and into the future.
