|
HS Code |
355505 |
| Product Name | 2-Amino-4-Methoxyphenol |
| Cas Number | 17672-87-6 |
| Molecular Formula | C7H9NO2 |
| Molecular Weight | 139.15 g/mol |
| Appearance | Light brown to orange solid |
| Melting Point | 140-144 °C |
| Solubility | Soluble in water and organic solvents |
| Purity | Typically ≥98% |
| Synonyms | Ortho-amino-p-anisole; 2-Hydroxy-5-methoxyaniline |
| Structure | A benzene ring with amino at position 2, hydroxyl at position 1, and methoxy at position 4 |
| Smiles | COC1=CC(=C(C=C1)O)N |
| Inchi | InChI=1S/C7H9NO2/c1-10-6-3-2-5(8)7(9)4-6/h2-4,9H,8H2,1H3 |
As an accredited 2-Amino-4-Methoxyphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The chemical 2-Amino-4-Methoxyphenol is packaged in a 100-gram amber glass bottle with a secure, chemical-resistant screw cap. |
| Shipping | 2-Amino-4-Methoxyphenol is shipped in tightly sealed containers, protected from moisture and light. The chemical should be handled as a hazardous material, complying with all relevant transport regulations. Proper labeling and documentation are required to ensure safe transit. Avoid extreme temperatures and ensure secure packaging to prevent leaks or spills during shipping. |
| Storage | 2-Amino-4-Methoxyphenol should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from heat, ignition sources, and incompatible materials such as oxidizing agents and acids. Protect from moisture and direct sunlight. Label storage clearly, and ensure access is limited to trained personnel wearing appropriate protective equipment. Store according to all relevant safety regulations. |
Competitive 2-Amino-4-Methoxyphenol prices that fit your budget—flexible terms and customized quotes for every order.
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2-Amino-4-Methoxyphenol draws attention as a versatile intermediate for a range of specialty applications. As a manufacturer with hands-on experience, we've observed its significance in the formulation of advanced dyes, pharmaceuticals, and fine chemicals. Chemists value this compound for its dual functional groups: an amino group in the ortho position and a methoxy group at the para position. This unique placement impacts both reactivity and the product's utility in synthesis work. The white or off-white crystalline powder offers consistent handling properties in batch production, allowing teams to scale up with fewer complications.
With a molecular formula of C7H9NO2 and a molecular weight of 139.15 g/mol, 2-Amino-4-Methoxyphenol brings predictable behaviors to reaction processes. The phenolic core stands out as crucial for coupling reactions and redox processes. Tight quality control on melting point and purity proves essential; experienced operators know small contaminant levels can cause headaches downstream, affecting color stability in dye manufacturing or leading to side products during pharmaceutical syntheses. Our process tuning delivers product in fine particulate form, often reaching purity levels above 99%, minimizing the risk of unwanted byproducts. We have found that controlled drying protocols preserve product integrity, avoiding oxidative browning—a point sometimes underestimated in commercial handling.
Industry relies on 2-Amino-4-Methoxyphenol beyond traditional bulk chemical roles. Its amine and hydroxyl functionalities grant flexible chemistry. In the dye sector, researchers leverage the compound for coupling reactions, creating molecules with nuanced shade control. The presence of the methoxy group shifts the electron density, making azo coupling less aggressive than with unsubstituted aminophenols. We've watched R&D teams harness this effect to generate redder or deeper violet dye structures, especially in hair coloring. These properties help colorists fine-tune hue sharpness and lasting power—critical qualities for market differentiation.
Pharmaceutical labs use it as a scaffold or intermediate during development of bioactive molecules. The structure acts as a useful entry point for further functionalization. In process chemistry, controlling reactivity offers peace of mind: the electron-donating methoxy group can temper the typical reactivity of aminophenol derivatives, sometimes opening up selective mono-substitution where harsher reagents would risk over-functionalization. Over the years, adjusting pH and solvent systems has allowed us to support syntheses where purity is non-negotiable. This has value for route scouting, where minor impurities might cause analytical challenges or meet regulatory scrutiny.
Reliable production of 2-Amino-4-Methoxyphenol takes more than following a recipe. Early on, our process engineers noticed that sourcing quality precursors directly affects batch reproducibility and downstream handling safety. We focus on optimized crystallization—balancing temperature and solvent recovery—since uneven crystal growth causes dusting, clumping, or filter clogging during isolation. Those issues snowball into downstream drying and packing headaches. Through continuous improvement, our facilities now achieve high batch yield and reliable moisture-controlled packaging, delivering consistent performance for every order. This minimizes re-testing and saves customers costly delays in their own operations.
Our lab teams perform regular GC and HPLC checks—not just on final product but on key intermediates. Over time, this practice has caught subtle shifts in side-product profiles, letting us tweak parameters before those shifts impact customers. We have learned to respond quickly: removing contamination at source rather than dealing with it by re-working stock. Higher-purity material feeds into fewer troubleshooting calls or product returns, building trust with R&D partners and production managers alike. Our logistics crew packs material in airtight, light-proof containers since photo-induced changes can affect color or solubility.
Customers often ask how 2-Amino-4-Methoxyphenol stacks up against other aminophenols or related compounds. The most common benchmarks are 2-Aminophenol, 4-Aminophenol, and their various alkoxy-substituted derivatives. Each brings its signature reactivity and downstream profile—selecting the right building block impacts not only product performance but also safety and waste management.
Compared to unsubstituted 2-Aminophenol, the methoxy group at the 4-position introduces a distinct electron-rich character. This affects both solubility in polar organic solvents and ease of nitration or oxidation. Dyestuff producers, for instance, often report sharper, more reproducible color transitions and less variation from batch to batch. Medicinal chemists see lower tendencies for unwanted cross-linking in multi-step sequences, which can otherwise force additional purification or yield losses. Alkoxy substituents in similar positions—whether ethoxy or propoxy—shift cost structures and reagent handling requirements. The methoxy variant offers a balance: robust enough for demanding reactions, cost-effective for scaled production, and manageable in hazardous waste planning.
Simple aminophenols can suffer from rapid air oxidation, causing storage and handling complications. We have found that 2-Amino-4-Methoxyphenol, by contrast, resists oxidative degradation under ambient warehouse conditions when tightly sealed. This extends shelf life and ensures predictable performance in the field. Some alkoxy derivatives dampen reactivity too much, forcing harsher reaction conditions or longer cycle times. Our product steps in with a “just right” level of activity for most flavor, fragrance, dye, and pharma applications—a result gathered from years working side-by-side with our partners to troubleshoot bottlenecks.
Operators handle large volumes of 2-Amino-4-Methoxyphenol daily, so we prioritize a safe and controlled environment. The powder releases limited dust but can irritate sensitive individuals with direct skin or eye contact. Our plant teams receive ongoing safety training and use well-ventilated charging bays to limit exposure during filling and sampling. PPE policies cover all steps—lab, batch, and warehouse. Although the material is not flagged as acutely toxic under current chemical safety guidelines, good housekeeping and cautious transfer methods reduce both your risk and ours.
Our journey toward greener manufacturing has pushed us to optimize not just process efficiency, but also effluent and waste profiles. Early process runs generated more organic by-product than ideal. Tightening temperature control, fine-tuning reagent addition, and improving post-reaction quenching now produce smaller waste volumes and reduce off-gassing. Solvent choice also plays a role. By investing in solvent recovery and recycling, our operations cut overall environmental footprint and reduce customer liability from solvent traces in final batches.
Solid waste management matters too. Our packing lines use heavy-duty, recyclable containers wherever possible. Shift teams minimize product spills through improved conveying and filling procedures. These straightforward changes not only reduce waste but also trim costs, proving that sustainable action and operational discipline can go hand-in-hand.
We learned early that no one enjoys unplanned surprises in their chemical feedstocks. Each lot ships with analytical data for purity, moisture, residual solvents, and key trace elements. By integrating in-process checks with finished product testing, we catch issues upstream. Analytical staff pull samples from throughout each batch—not just top or bottom—since uneven mixing or drying can produce non-representative results. Our preferred analytical methods build on validated industry norms, but we also listen to customer suggestions for custom test parameters. Real-time adjustments have helped catch outliers before they leave the plant.
Storage conditions impact product quality. Our customers carry these lessons home, but as a manufacturer, we also test real-world storage durability. We stock small samples in production and non-production settings, then re-analyze periodically. This practice catches rare problems—such as slight yellowing from unanticipated light exposure—making it easier for clients to plan shelf lives and avoid service interruptions. Automated packing lines fill containers in an oxygen-limited environment, adding peace of mind for customers concerned about color stability.
Batch consistency ranks highly among pharmaceutical and dye customers. Over years of feedback, we have honed in on narrow tolerances for key quality indicators. Subtle changes in plant utilities or precursor purity can shift product characteristics outside defined windows, risking off-spec runs. To stay ahead, our technical team tracks plant data in real time, flagging any drift and launching root-cause investigations before shipments go out.
Manufacturing rarely sticks to a script. Raw material variations, equipment wear, or utility issues can shape final product features in subtle but important ways. When problems come up, we jump into root-cause analysis with urgency—bench chemistry, supplier checks, process simulation, and customer feedback loop into actionable fixes. Over time, experience has taught us to involve all stakeholders: plant floor, lab staff, engineering, and the customers themselves. We believe honest communication and a willingness to adjust pay dividends for all involved.
Last year, a supplier’s solvent changed grade, unnoticed in their documentation. Our process upsets led to a few batches with color out of spec—not immediately apparent in early QC. Customers called us before we could notify them. Working together, we tweaked both supplier monitoring and our own analytical catch points, restoring confidence and minimizing further downtime. Honest lessons from these wrinkles bind supplier and user together. It’s not simply about process chemistry, but about keeping open lines and mutual understanding.
2-Amino-4-Methoxyphenol serves as a building block for a surprising spectrum of end products. Its adaptability fits the diverse requirements of dye houses, pharmaceutical labs, cosmetics developers, research institutes, and specialty chemical plants. Requests for tailored grades—smaller particle size, low moisture, or tighter trace element controls—underscore the need for flexibility. Our own technical teams collaborate often with end users to understand new regulatory requirements, downstream processing updates, and innovation trends.
No chemical operates in isolation. As regulations and application requirements evolve, we see growing interest in cleaner, safer, and more sustainable sourcing. Customers often ask for lower impurity profiles to anticipate stricter guidelines or to improve downstream yields. We have responded by fine-tuning upstream reaction clean-ups, investing in process automation, and deepening raw material vetting. The result is a product better aligned with end-market needs and easier to certify for advanced manufacturing routes.
Innovation sometimes comes from unexpected quarters. In discussions with R&D chemists working in OLED materials, bioactive compounds, and analytical reagents, new applications for 2-Amino-4-Methoxyphenol continue to surface. Its compatibility with both mild and robust reaction conditions has opened unexpected avenues in new materials research and custom synthesis. We commit to keeping a feedback loop open, sharing practical experience and facilitating new product testing for specialty applications. This culture of iteration and partnership encourages better outcomes on both sides of the production chain.
Experience on the manufacturing floor shapes every aspect of the product journey. Day-to-day attention to filtration, drying, blending, and packing prevents many common headaches that can escalate once the product reaches a customer. Our crews resolve filter plugging, ensure that crystals remain free-flowing, and avoid introduction of unwanted moisture during packing. Occasionally, even slight changes in plant temperature or a shift in operator practice can filter down into altered performance. By tracking these variables and implementing ongoing operator training, we've reduced batch-to-batch deviation and earned repeat trust from demanding sectors.
Large-scale users—those running tens of metric tons per year—appreciate not just product quality, but tight response times and transparent communication. Unexpected holdups in global shipping or plant shutdowns for preventive maintenance will happen; sharing those realities promptly enables customers to adapt their own workflows. We recognize the value of direct access to technical staff rather than navigating endless layers of customer service, because competent troubleshooting often hinges on simple, rapid conversation.
Smaller customers, such as boutique dye houses or research labs, find the material’s consistency just as essential. These teams sometimes need rapid shipment of small quantities, and over the years, we've streamlined order processing and inventory allocation to accommodate urgent or specialized requests. We keep technical documentation up-to-date and accessible, supporting compliance checks or grant applications efficiently.
Behind every kilogram of 2-Amino-4-Methoxyphenol stands a chain of trust and expertise. Our relationships with upstream suppliers, our plant operations culture, and our ongoing dialog with end users all combine to determine the practical value customers receive. As the manufacturer, we recognize that every challenge on our side ripples into our partners’ processes. By taking responsibility for tight control, open communication, and continuous improvement, we help support innovation and productivity across the supply chain.
Responsive manufacturing only works when knowledge moves in both directions. Improvements in plant safety, waste reduction, or batch consistency often start with a comment or a concern raised by someone on the customer’s production or R&D team. We keep lines open not only for troubleshooting but also for early signals of shifting market needs or new regulatory expectations. Manufacturers inform, adjust, and collaborate because mutual success depends on keeping the full picture in view.
2-Amino-4-Methoxyphenol’s journey from raw materials to the end user's bench contains countless moments of intervention—each shaped by technical know-how, practical experience, and shared goals. That process builds more than product; it builds confidence across industries and enables practical innovation at every step.
