Anhui Liwei Chemical Co., Limited
Products

2-Acetyl-4-Isopropylphenol


    • Product Name 2-Acetyl-4-Isopropylphenol
    • Alias Grifolin
    • Einecs 225-582-5
    • Mininmum Order 1 g
    • Factory Site Lingwu, Yinchuan, Ningxia, China
    • Price Inquiry sales2@liwei-chem.com
    • Manufacturer Anhui Liwei Chemical Co., Limited
    • CONTACT NOW
    VTB
    Specifications

    HS Code

    489739

    Cas Number 14693-23-1
    Molecular Formula C11H14O2
    Molecular Weight 178.23
    Iupac Name 1-(4-isopropyl-2-hydroxyphenyl)ethan-1-one
    Appearance Colorless to pale yellow liquid
    Boiling Point 304°C
    Solubility In Water Slightly soluble
    Density 1.06 g/cm³
    Refractive Index 1.525
    Flash Point >110°C
    Smell Characteristic, phenolic

    As an accredited 2-Acetyl-4-Isopropylphenol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 250g of 2-Acetyl-4-Isopropylphenol is supplied in a sealed amber glass bottle with a secure screw cap and detailed labeling.
    Shipping 2-Acetyl-4-Isopropylphenol should be shipped in accordance with local and international regulations for chemicals. Use tightly sealed containers, clearly labeled with hazard information. Transport in a cool, dry, and well-ventilated area, protected from direct sunlight and incompatible substances. Ensure packaging prevents leaks and complies with safety and environmental guidelines.
    Storage 2-Acetyl-4-Isopropylphenol should be stored in a tightly sealed container in a cool, dry, and well-ventilated area, away from direct sunlight, heat sources, and incompatible materials such as strong oxidizing agents. Ensure the storage area is appropriately labeled and equipped to handle chemical spills. Avoid contact with moisture, and store at room temperature, keeping the container upright to prevent leaks.
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    Tel: +8615380400285

    Email: sales2@liwei-chem.com

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    Certification & Compliance
    More Introduction

    2-Acetyl-4-Isopropylphenol: A Essential Ingredient with Growing Demand

    Understanding 2-Acetyl-4-Isopropylphenol in the Manufacturing World

    Choosing the right ingredients makes a difference in product performance, and 2-Acetyl-4-Isopropylphenol reflects this better than many specialty chemicals. We've spent years in hands-on manufacturing, pushing for consistent yields and reliable supply. This compound often gets called by its trade or short names, but chemists across research, flavor, and fragrance industries recognize it instantly from its distinctive aromatic profile and chemical stability.

    The compound’s formula, C11H14O2, and a molecular weight close to 178.23 g/mol, put it in a class of phenolic substances optimized for multi-industry use. From the earliest days of manufacturing, we saw interesting behavior — stability under heat, predictable reaction rates, and desirable organoleptic characteristics. Unlike simple phenols, the acetyl and isopropyl substituents on its aromatic core tune both its reactivity and aroma, letting formulators strike a balance between intensity and longevity.

    Testing each batch in our own labs before shipment, we've learned how subtle variations in raw material or purification route can impact the purity. For our standard grade, we target 99% minimum purity, controlling water and ash content to under 0.5%. Excessive moisture or trace metal contamination can undermine end-use performance, so we never take shortcuts on raw material screening, column purification, or vacuum drying.

    Safety remains central not just in our plant but for every customer’s operation. Our workers, wearing basic personal protective equipment, monitor for dust or vapor build-ups—this compound produces a strong, sweet-phenolic odor that signals its presence long before concentrations rise to problematic levels. We always recommend handling it in ventilated production rooms and avoid direct skin contact. In decades of batch handling, we have never seen ignition hazards at normal application concentrations because the flash point sits well above room temperature, but we emphasize awareness if processed near open flames.

    Why Formulators Choose 2-Acetyl-4-Isopropylphenol

    Chemists and fragrance engineers reaching for this molecule point to its unique aroma: a combination of peppery, sweet, and slightly woody notes. The aroma profile led to its early adoption in perfumery, particularly in formulations seeking a spicy backbone without overpowering floral or citrus notes. Years of feedback from customer trials taught us that a modest dosage transforms the blend, giving colognes, soaps, and detergents an unmistakable signature.

    Beyond fragrance, pharmaceutical and agrochemical customers value its chemical robustness. We've supported process R&D teams searching for an intermediate that tolerates alkaline and mildly acidic conditions without decomposing. The structure also accommodates further synthetic transformations, enabling downstream production of antioxidants, antimicrobial agents, or advanced flavor enhancers. Batch-to-batch consistency, both in aroma and assay, often makes the difference between a successful product registration and costly troubleshooting.

    Flavors benefit as well from the molecule’s balanced solubility in polar and non-polar matrices. Beverage and food developers demand both stability and clean background notes; this compound delivers. It resists off-flavors even under long storage or mild heating. Our experience has shown it integrates cleanly in formulations containing alcohol, glycols, or plant extracts, avoiding the “clouding” or loss of volatility that plagues many weaker aroma chemicals.

    Comparing 2-Acetyl-4-Isopropylphenol with Related Molecules

    Few specialty compounds mirror the functional blend found here. Standard acetophenones or cresols lack the depth or fine-tuned odor profile. We regularly work with clients who tried eugenol, thymol, or simple phenol derivatives, only to find unraveling compositional challenges. Either volatility exceeded the limits of desired persistence, or the basic reactive core triggered unexpected byproducts during shelf life.

    What sets 2-Acetyl-4-Isopropylphenol apart is the simultaneous control of volatility and sensory sharpness. The isopropyl group adds bulk, slowing down release in air and anchoring the aroma longer. The acetyl group softens perceived sharpness while ensuring the molecule maintains solubility in most organic solvents—including ethanol, DPG, and some natural oils. This compatibility allowed several flavorists and fragrance artists we collaborate with to design cost-effective, shelf-stable blends for high-throughput consumer products.

    Customer technical teams who moved between similar aroma chemicals report smaller swings in performance and fewer “ghost” notes when they use our product. This saves lost labor hours in production adjustment and shortens QC cycle times. Recent requests showed demand from manufacturers producing air care, floor cleaners, and personal care items that must retain their signature scent for months or years after bottling. In direct testing, blends built around this molecule show better retention and consumer appeal than those relying on more volatile phenolic or acetophenone bases.

    Even solvent-blending companies looking for specialty bases noted that 2-Acetyl-4-Isopropylphenol delivers greater freedom in finished product design. Standard substitutions often require overcompensation elsewhere in a recipe, raising costs or altering the skin-feel in cosmetics. Years spent troubleshooting formulations in partnership with customers allowed us to see this firsthand: choosing this compound means fewer formulation headaches, lower raw material costs, and simpler regulatory documentation.

    Production Insights and Supply Chain Realities

    We’ve managed every step in the production chain, from raw material synthesis to quality control. Early routes used Friedel–Crafts acylation, but newer catalytic techniques let us cut down on waste and achieve more predictable yields. Controlling reactor temperature and solvent purity makes the difference between substandard yield and shipments that meet the highest benchmarks. Our operators track production runs down to the hour; we invest in in-line analytical sensors to flag batch inconsistencies before final purification.

    Shipping regulations require tight packaging and labeling, but with its low acute toxicity and stable composition, bulk storage presents few surprises. We fit the needs of global manufacturing plants by offering grading schemes certified by recognized laboratories, partnered with our own routine in-house testing. We noticed over time that extra vigilance during last-mile transport cuts down on residual moisture pickup and flavor cross-contamination in multi-product facilities.

    Clients want to plan months or years out, and we aim for certainty. Having operated through raw material shortages, demand spikes, and shifting export rules, we never take stockpiling and regular contract fulfillment for granted. We work closely with long-term buyers to forecast, coordinate third-party testing when needed, and keep transparent logs of changes in raw material sources. Our technicians regularly attend industry meetings to keep current on regulatory trends around phenolic ingredients—especially as more markets demand low-impurity profiles and traceability.

    End-Use Considerations Driving Adoption

    Experienced blenders and product designers recommend starting low, typically around 0.02–0.1% by weight in final goods. Stronger concentrations rarely provide better aroma or psychoactive effects and risk overpowering supporting notes. We see the best performance in liquid fragrance blends, solid air fresheners, and soap bases where slow release matters most. Households and consumers increasingly look for authenticity in aromas; formulators praise the subtlety and warmth this molecule can add without “synthetic” off-notes.

    Several agricultural technology companies work with us to develop plant protection blends that need antimicrobial action while remaining non-phytotoxic. This phenolic structure offers the right balance for these advanced applications, delivering an effective barrier without harming plant tissue or degrading shelf-stable formulations. On the pharmaceutical side, we respond to regular requests centered around antioxidant blends and specialty actives meant for controlled delivery, precisely because our quality records show tight batch conformity.

    End manufacturers of processed foods, especially snack and beverage innovators, integrate the molecule for its flavor-modulating properties and low reactivity with common packaging. Regulatory teams audit our supply chains for traceability and absence of banned impurities, so our quality systems revolve around full transparency from raw material entry to end shipment. Few things matter more to customers than the confidence in knowing every drum, tote, or kg bag performs just as lab-certified samples promised.

    Practical Handling and Storage in the Real World

    On the shop floor, operators open drums with built-in venting or vapor recovery, since the compound’s strong aroma fills the air quickly. Spills rarely pose safety hazards in normal settings, but we keep absorbent media and neutralizing agent within reach, both to protect workers and prevent product loss. Years have taught us that careful drum stacking and temperature control—ideally 15–25°C storage—guarantee an 18-month shelf life, even through seasonal fluctuations or extended transit times.

    We receive calls about incorporating 2-Acetyl-4-Isopropylphenol in existing lines with minimum downtime. Success comes from careful trial runs and pilot-scale testing alongside the main batch. Our technical teams support these transitions, helping with cleaning protocols, dosing optimization, and blending order. Taking the time upfront aligns batch processing with downstream filling or switching, meaning output hits spec from the first run. Customers using older open-kettle technology adapt modern mixer controls; this ensures even distribution and safe emissions capture.

    Waste Management and Environmental Impact

    Environmental regulations evolve, and chemical producers can’t ignore disposal obligations. This compound breaks down by standard thermal and catalytic incineration, producing minimal hazardous byproducts if handled properly. Our waste handling crews sort and track all off-spec, expired, or spilled material—recycling solvent where feasible and collaborating with certified waste processors for the rest. Compared to some legacy phenols, this compound’s low acute aquatic toxicity and rapid breakdown ease disposal in developed-market jurisdictions.

    We keep records and work with regulators to address local water and air discharge rules. Newer site upgrades implemented continuous air scrubbing and both liquid and solid spill containment, further reducing the remote risk of environmental incidents. The global trend toward greener supply chains gradually shapes every product and process; our R&D teams pursue further process intensification and seek greener raw material paths when commercial feasibility and product integrity align.

    Regulatory Landscape and Transparency

    Each market requires documentation demonstrating compliance: EU REACH, US TSCA, and food additive rules in jurisdictions where customers request flavors. We provide suppliers’ declarations and product dossiers as needed. Over the years, inspection teams visiting our plant have cited our factory for up-to-date logs, accessible analytical records, and regular third-party audits. Because each client receives clear batch records and impurity documentation, product registration and safety filings run smoothly—no surprises, no “hidden” nonconformities discovered down the line.

    End-users increasingly ask about plant energy usage, recycled packaging, and the absence of banned substances. We adapted quickly: updated digital recordkeeping, new certified drum liners, and full ingredient disclosure accompany every major shipment. International regulatory teams occasionally audit our processes or request detailed impurity spectra; our standard response is to open the lab books and invite direct sample reviews.

    Practical Solutions for Ongoing Challenges

    Challenges in specialty chemical manufacturing rarely repeat exactly year by year—input prices shift, demand for “natural” or “bioidentical” chemistry increases, and competitors push for lower costs regardless of real purity. We learned over time to invite customer feedback into our own process design cycle, from requests for finer granulation to improved labeling or eco-friendly transit packaging. Customers designing products for sensitive users—children, elderly, or asthmatic consumers—sometimes need even stricter contamination thresholds. Our process engineers install dedicated transfer lines or invest in upgraded filtration to meet those demands.

    Supply chain resilience remains on our agenda. We keep alternate supplier agreements, internal raw material stockpiles, and contingency production capacity. If raw material sources dry up or logistics falter, we alert buyers quickly and align backup supplies on priority orders. No bottleneck exposes weaknesses in the modern supply chain like a chemical outage, so our sales and technical teams keep direct channels open with global partners.

    Digital systems now underpin every major process, with real-time lot tracking, predictive maintenance for blending/apparatus, and periodic training for staff on emerging good practices. These measures reduce operator error, cut batch losses, and guarantee that the compound customers receive mirrors every expectation set by our analytical or application teams. We invite technical partners and customer QA teams to review our safety, traceability, and performance metrics at any time—building shared knowledge that pushes everyone forward.

    Why Direct Manufacturer Relationships Matter

    Over years working shoulder-to-shoulder with customers, we've seen the trust built by open, direct dialogue. Everyone in production feels the pressure to find higher-performing, more sustainable, and more reliable raw materials. Our commitment to transparency, in-plant QC, and ongoing improvement delivers results that can't come from anonymous intermediaries or loosely overseen supply chains. Misunderstandings slow down launches and risk non-compliance; open relationships and technical feedback keep everything moving in the right direction.

    We take pride not just in consistently delivering drums of 2-Acetyl-4-Isopropylphenol, but in supporting our customers as they push into new markets or face unexpected regulatory questions. The feedback loop never stops: everyone from R&D chemists to line operators and regulatory auditors contributes to better process design, safer handling, and the next generation of performance improvements.

    As customer needs evolve, the value of a well-supported, high-performance ingredient only grows. The years spent perfecting the manufacture and delivery of this specialty compound pay dividends for everyone seeking standout aroma, flavor, or function in demanding applications. In the end, deep manufacturing know-how remains the strongest guarantee of product quality, consistency, and compliance—each batch, every time.