|
HS Code |
714261 |
| Product Name | 2,5-Dibromohydroquinone Dimethyl Ether |
| Synonyms | 2,5-Dibromo-1,4-dimethoxybenzene |
| Cas Number | 5342-51-4 |
| Molecular Formula | C8H8Br2O2 |
| Molecular Weight | 312.96 g/mol |
| Appearance | White to off-white crystalline solid |
| Melting Point | 145-148 °C |
| Boiling Point | 325 °C (estimated) |
| Solubility | Soluble in organic solvents such as chloroform and dichloromethane |
| Density | 1.98 g/cm³ |
| Purity | Typically ≥98% |
| Storage Conditions | Store in a cool, dry place away from light |
| Smiles | COC1=CC(=C(C=C1Br)OC)Br |
| Inchi | InChI=1S/C8H8Br2O2/c1-11-7-4-6(9)5-8(10)3-7(2)12-11/h3-5H,1-2H3 |
As an accredited 2,5-Dibromohydroquinone Dimethyl Ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The product is supplied in a 25g amber glass bottle, sealed with a screw cap and labeled with chemical details and safety warnings. |
| Shipping | 2,5-Dibromohydroquinone Dimethyl Ether is shipped in tightly sealed containers, protected from light, moisture, and incompatible substances. It is transported following relevant regulations for hazardous chemicals, labeled appropriately, and handled with care to prevent leaks or spills. Shipment is typically conducted via certified chemical carriers with proper documentation and safety protocols. |
| Storage | 2,5-Dibromohydroquinone Dimethyl Ether should be stored in a tightly sealed container, in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances (such as strong oxidizers). Protect from moisture, light, and excessive heat. Clearly label the container and keep it in a designated chemical storage area, following all relevant safety and regulatory guidelines. |
Competitive 2,5-Dibromohydroquinone Dimethyl Ether prices that fit your budget—flexible terms and customized quotes for every order.
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Every batch tells a story, and in forty years of manufacturing aromatics, 2,5-Dibromohydroquinone Dimethyl Ether continues to teach us the same lessons about consistency, purity, and what researchers genuinely need. Inside our reactors, this compound is not some abstract raw material. Its performance stakes run high, especially when biotech innovation or pharmaceutical synthesis pushes for exacting standards. Our staff members memorize its CAS number, 1005-90-7, not from paperwork routine, but from daily volumes handled, from quality control logs, from feedback and troubleshooting with formulators in real time.
We see orders pass the loading bay for the powder, typically off-white and handled safely in moisture-free rooms. Decades of weighing, analyzing, and reformulating have taught us: unwanted byproducts can throw an entire multi-stage synthesis off. While chemistry departments often look for speed and efficiency, they soon realize the value of reliable, predictable starting points–especially where targeted substitution and halogen atom placement are critical.
We have tailored the process for 2,5-Dibromohydroquinone Dimethyl Ether, also called 1,4-Dimethoxy-2,5-dibromobenzene by some, based on chemist feedback and results, not just catalog targets. Most orders demand a minimum assay of 98%, but several pharmaceutical partners push for 99% or better, with strict moisture control and minimal organic impurities. Potential bromine substitution side reactions are tracked batch after batch via HPLC–analyzing trace contaminants could mean the difference between a clean separation in a downstream step and a costly rework.
Physical characteristics seem simple on the page: a fine crystalline powder, stable when kept away from light and humidity, and easy to dissolve in a range of nonpolar or slightly polar solvents. Talking with research departments, the concern often comes down to thermal stability and handling: our product can tolerate standard drying steps and mild heating during workup without darkening, thanks to precise crystallization and filtration methods we have refined over years.
This isn’t a commodity feedstock that moves in rail cars by the ton. 2,5-Dibromohydroquinone Dimethyl Ether typically serves medicinal chemistry and specialty materials fields, where its twin bromine atoms activate the benzene ring for substitution. The two methoxy groups further nudge reactivity: they control electron distribution, opening routes to complex targets that simpler dibrominated benzenes can’t deliver. Our partners in small-molecule drug discovery reach for this compound to build more elaborate aryl ethers and diaryl compounds, unlocking scaffolds not easily constructed from other building blocks.
In more than one project, the selection of 2,5-Dibromohydroquinone Dimethyl Ether has cut several steps out of the synthetic route. Where alternatives, such as 1,4-dibromo-2,5-dimethoxybenzene or mono-methoxy substituted versions, might require protecting groups, correction stages, or are simply less stable when storing intermediates, our product consistently supports faster, cleaner transformations. It’s a niche role, but it answers the persistent need for advanced functionalized building blocks without convoluted protection-deprotection cycles or the unpredictability of isomeric purity from larger suppliers.
Some buyers try to compare this compound to the more widely available symmetrical dibrominated aromatics. In practice, the simultaneous presence of electron-donating methoxy groups can fine-tune both the solubility profile and the reactivity, resulting in more selective halogen-metal exchange reactions. This minimizes side reactions and increases yield for target intermediates, especially in stepwise syntheses geared toward active pharmaceutical ingredient (API) cores.
The origin of raw materials is more than a purchasing bullet point. We work only with bromine and hydroquinone suppliers that provide consistency, and every drum of precursor can be traced back in our logs. Variability upstream is enemy number one for our purification team, which is why crude product rarely gets signed off before full QA–a practice that some traders or repackers neglect, especially when a product seems ‘easy’ to produce on paper. Over the years, our technical team has seen lesser batches from external brokers, carrying faint yellow tints or slurries, hinting at over-bromination or insufficient washing; these simply don’t pass muster for downstream applications in our customer base, who often use this material as a precursor to sensitive bioactive molecules.
Every new process improvement, from adjusting crystallization pH to extending filtration, comes from feedback: failed chromatography runs in partner labs, months spent training yields up in multi-step programs, or direct analysis reports highlighting trace impurities. We’ve learned to put in the extra analytical step, whether it looks necessary or not, because our buyers don’t have time for failed scale-ups or ambiguous H-NMR peaks in escalated projects.
Feedback from synthetic chemists often focuses on flexibility–not in shelving inventory, but in executing creative and sometimes time-sensitive routes to targets. The unique substitution on this compound becomes indispensable when conventional halogenated benzenes bog down in sluggish or low-yielding couplings.
Take the case of academic groups assembling advanced phenolic ethers: the methoxy protection provided by our product eliminates the need for temporary masking. In industrial pilot studies, side reactions get suppressed, and final product isolation is consistently cleaner, yielding sharper melting points and reducing the need for repeat purifications. Often, research teams return to us with observations on crystallinity, shelf life, or how a particularly stubborn cyclization worked on the first try–after months of frustration using generic, off-brand intermediates.
People in academic settings sometimes ask about the differences between this compound and its mono-brominated or mono-methoxy cousins. The answer comes down to both reactivity and reliability. Mono-substituted variants offer less control when targeting multi-point functionalization, leading to mixtures that complicate isolation and characterization. For pharma projects, that difference can translate to weeks of extra work and thousands of dollars wasted on purification that adds no value to the final product. We’ve remained strict on batch release criteria simply to protect our downstream partners from such pitfalls.
Lab managers inquire about scale. We have refined the scale-up over years–no jump from grams to kilograms happens without a process review. In our hands, controlling exotherms during bromination, staged dosing, and real-time monitoring avoids the off-odors and rare tars that sometimes show up in less experienced shops. What leaves our site matches the sample submitted for your pilot studies, right down to particle size and trace moisture content.
Every manufacturer faces the burden of responsible production, especially since halogen chemistry introduces risks not only in process safety but also in downstream waste. Over several process iterations, we have reduced the generation of high-DBE (double bond equivalent) organics, recovering solvents where possible and recycling wash streams according to regulatory guidance. Monitoring for residual solvents and brominated byproducts isn’t just a box-check–it drives customer trust and delivers a better product for workers and end users.
Handling this material in a manufacturing environment—or even in a lab—doesn’t come without its lessons. Any slip in containment or drying protocols can trigger decompositions or result in batch colorations that downstream labs cite in their chromatography notes. Employees are reminded regularly that personal protection and containment should follow robust protocols, and we conduct regular drills to avoid even minor exposures. Decades of working with benzenes and bromine have built a culture of vigilance: not just for compliance, but because everyone in our team knows that one slip can undo the predictability that our customers count on.
Our investment in this product tracks back to increasing requests for more selective halogenated building blocks for medicinal chemistry. Over time, real-life requests like tighter impurity specs, more robust packaging against atmospheric moisture, and even custom particle size distributions drove our technical output. This back-and-forth dialog has forced us to stay nimble; upgrading filtration, switching drying technologies, and periodic recalibration of analytical methods became routine.
One improvement that stuck involved a switch from atmospheric to vacuum drying. The adjustment not only improved the shelf life but also reduced trace byproducts that subtly affected yields in biaryl coupling reactions. We measure each new process in real customer KPIs: cleaner NMR readings in the hands of a research scientist, sharper melting point ranges for scale-up trials, and feedback directly from the chemists using the materials under stress.
We recognize 2,5-Dibromohydroquinone Dimethyl Ether isn’t always the star of a multi-stage pharmaceutical synthesis or advanced material prototype. It’s usually found two or three steps deep in a synthetic scheme–rarely discussed outside process teams or formulator phone calls. But without dependable intermediates, whole projects can stumble: failed couplings, inconsistent characterization, delayed delivery of project milestones.
It’s not just about meeting a certificate of analysis. Consistency batch to batch remains our hallmark. We have witnessed the cost of skipping rigorous quality checks: even a 0.5% shift in assay or a hidden contaminant can throw off expensive project stages. Because of this, we built in regular external benchmarking and in-house replicates. Our tech staff interacts directly with many of the stakeholders using our materials, so dialogue remains open and we chase improvement across every campaign.
Access to low-cost alternatives from brokers or third parties can distort the market for key intermediates. From our vantage point, the differences manifest in places a procurement department may not see: delayed analytical reports, shipment issues, unexpected melting point depression, or the horror of failed pilot runs that set innovation back by quarters. We have been called in on more than one occasion to troubleshoot, trace root causes, and offer corrective material–sometimes just days before a critical deadline. Each time, the lesson echoes: genuine accountability in manufacturing translates to less project risk for everyone downstream.
Every drum shipped out comes with a unique batch history. We maintain decades of records for raw material certifications. That attention to traceability spares our partners late-stage surprises on regulatory or environmental questions. It’s not a marketing flourish; it’s a direct outgrowth of the feedback loop we keep open with every customer, and of lessons learned responding to material recalls or tracing contaminants back up the supply chain.
Glass lining in large containers, robust multi-layered liners in all export shipments, and strict moisture barrier requirements are now standard. Feedback from overseas partners flagged even minor moisture ingress over long-haul transit in early years, prompting us to overhaul drum lining specifications. Those changes minimized clumping and ensured product behaves as expected upon arrival.
Not every producer wants to acknowledge the challenge of international shipment, especially for materials that must arrive in top shape, despite delays or exposure to variable climates. We worked through more than one customs delay to find out exactly which points in the journey could expose a shipment to risk. This is why we log every carrier and why our warehouse team contacts recipients directly during any irregularity–so a compound that leaves our gate in spec doesn’t risk its function upon delivery.
We wouldn’t have refined this product without constant contact with chemists, pilot plant engineers, and regulatory affairs teams. Every tweak in process stems from questions and reported issues: should we pre-grind for certain applications? Is HPLC reporting accurate enough? Can we support audits with depth, not just surface answers?
Direct customer engagement brings our R&D team onto calls when necessary, so that changes in analytical methodology or the need for alternative packaging are properly communicated. Nothing is left to email chains. It’s a direct response model, honed over decades in fields that permit little margin for error.
From our perspective, producing 2,5-Dibromohydroquinone Dimethyl Ether is not about marketing an SKU. It means owning every step–from raw material vetting to process optimization, to honest feedback sessions with users onsite or hundreds of miles away. The difference between a commodity supplier and a true manufacturing partner lies in how issues are handled, how feedback translates into better process control, and whether every person on the team understands why precision matters: not only for our batch, but for the hundreds of scientists and engineers whose work builds on what we deliver. Each kilo represents a piece of trust, and we strive to earn it with every lot that leaves our doors.
