|
HS Code |
423122 |
| Chemical Name | p-Chloro-m-Cresol |
| Synonyms | PCMC, 4-Chloro-3-methylphenol |
| Molecular Formula | C7H7ClO |
| Molecular Weight | 142.58 g/mol |
| Cas Number | 59-50-7 |
| Appearance | White to off-white crystalline powder |
| Melting Point | 64-66°C |
| Boiling Point | 235°C |
| Solubility In Water | Slightly soluble |
| Odor | Phenolic odor |
| Purity | Typically ≥99% |
| Ph Value | 5.5-7.0 (1% solution) |
| Density | 1.3 g/cm³ |
| Logp | 2.2 |
| Stability | Stable under normal conditions |
As an accredited P-Chloro-M-Cresol (Pcmc) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | P-Chloro-M-Cresol (PCMC) packaged in a sealed 25 kg HDPE drum with clear labeling, hazard warnings, and batch details. |
| Shipping | P-Chloro-M-Cresol (PCMC) is typically shipped in tightly sealed containers, such as HDPE drums or fiber drums, to prevent contamination and moisture absorption. Containers are clearly labeled and transported according to hazardous material regulations, ensuring a cool, dry, and well-ventilated environment to maintain product stability and safety during transit. |
| Storage | P-Chloro-m-Cresol (PCMC) should be stored in a tightly sealed container at room temperature, away from direct sunlight, heat, and moisture. Store in a cool, dry, well-ventilated area, separated from incompatible substances such as strong oxidizers and acids. Ensure proper labeling, and keep out of reach of unauthorized personnel. Always adhere to local safety regulations for chemical storage. |
Competitive P-Chloro-M-Cresol (Pcmc) prices that fit your budget—flexible terms and customized quotes for every order.
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Standing on the production floor, you get a sense for what separates true quality from mere commodity in specialty chemicals. We have devoted decades to perfecting our P-Chloro-M-Cresol (PCMC), a compound with the chemical formula C7H7ClO, known in the chemical industry for its stable preservation profile and compatibility with a broad range of formulations. Each batch that leaves our facility reflects rigorous monitoring, real-world testing, and a commitment to tight chemical specifications.
PCMC often enters the conversation as an antimicrobial ingredient. Many have heard about it under its common synonym, Chlorocresol, primarily used across pharmaceutical, personal care, and industrial formulations. Our direct involvement gives a firsthand perspective on why end users continue to return to this compound, even as newer preservatives come and go.
The distinguishing factor with PCMC always comes down to its remarkable microbial inhibition capability, paired with impressive chemical stability. In day-to-day operations, we watch production managers in pharmaceutical plants rely on it for topical formulations, ointments, and creams, thanks to its broad-spectrum activity against gram-positive and gram-negative bacteria, fungi, and yeasts. With high batch consistency, formulators do not have to worry about unpredictable preservative action, a detail we focus on relentlessly as a core manufacturer.
Our PCMC’s melting point typically hovers just above 65°C, and it appears as a white to pale pink crystalline powder. The color may vary slightly depending on trace impurities, but we maintain a tight rein on purity—typically above 99%. The faint phenolic smell is a sign of authenticity, something anyone who has measured out these powders in a compounding laboratory will immediately recognize.
We produce PCMC in grades suitable for cosmetics and pharmaceuticals, with a clear understanding that impurity levels make a significant difference in formulations that need to meet global regulatory standards. Water solubility remains modest, so dissolving it calls for ethanol or alkali solutions in many processes. By working closely with R&D teams, we ensure practical insight into solubilization challenges and help troubleshoot unusual precipitation during mixing or storage.
In daily manufacturing, purity matters as much as price. Our experience shows that minor contamination—whether from chlorinated dibenzodioxins or other chlorophenolics—leads to headaches ranging from product recalls to stability failures in creams and ointments. Decades of process refinement have taught us which steps influence side-product formation, and our line operators know precisely how to minimize trace contaminants.
Sterile environments, such as those maintained for injectable and ophthalmic preparations, call for unwavering trust in preservative performance. A slightly off-spec batch can compromise months of effort. Because we manufacture our PCMC under strict validated processes, major pharmaceutical firms continue to specify us as a supplier of choice for critical applications.
Beyond the pharmaceutical sector, formulators in adhesives, paints, and cutting fluids rely on PCMC to fend off spoilage, especially in environments subject to high humidity or intermittent opening. Our chemical is compatible with both water-based and oil-based systems, giving it an edge over many quaternary ammonium or parabens-based alternatives. Even after years of industry shifts, customers often stick with what works—PCMC remains top of list for time-tested preservation.
Many come to us with questions about how PCMC performs next to phenoxyethanol, methylparaben, or triclosan. After years of fielding these questions, it’s clear that direct experience offers the best answers.
PCMC serves as both bactericide and fungicide, disrupting cell wall synthesis via protein denaturation. Unlike parabens, it keeps activity across a wider pH range—especially crucial in products with slightly alkaline profiles. Triclosan, on the other hand, struggles with regulatory bans and rising resistance, while phenoxyethanol falls short on yeast inhibition. PCMC covers a balance of broad antimicrobial action and formulation compatibility, making it the mainstay for products that require long open-shelf stability.
More than once, we’ve seen formulators try to swap out PCMC for newer preservatives, only to return due to batch instability or consumer irritation complaints. Consistent particle size and high purity underpin this difference. Our production teams regularly analyze the interaction between PCMC and typical emulsion systems; this up-close look reveals how small changes in manufacturing lead to significant changes in finished product shelf life.
Our factory floors see a steady demand for documentation—COAs, batch records, impurity profiles. We understand these requests are not bureaucratic hurdles. They reflect deep concerns from QA teams facing ever-tightening audit standards. Through years of regulatory inspections, every process step, from raw material sourcing to drying and micronization, has been under a microscope.
Our PCMC meets and exceeds the pharmacopoeial specs set by EP, USP, and BP. We maintain low moisture content and suppress heavy metals below regulatory thresholds. Particle size control is one of our biggest differentiators; improper milling leads to poor dispersion, which causes cloudiness or lumping in finished creams and lotions. In our experience, finer particle sizing translates to ease of handling and better flow during batch mixing—a detail ignored by less specialized manufacturers.
End users consistently share similar stories: stable product, extended shelf life, fewer complaints in the field. The correlation points back to high batch-to-batch reproducibility, underpinned by robust QA systems on every shift, every month. We continually invest in advanced HPLC and spectroscopic techniques to guarantee every shipment mirrors the prior one, without fail.
As practitioners in chemical manufacturing, safety doesn’t only live in the SDS. On our lines, correct ventilation, up-to-date PPE, and meticulous dust management stop issues before they start. PCMC produces irritating dust when handled carelessly. Over the years, operators new to the material find their tolerances the hard way. Our safety trainers stress correct transfer methods and double-check PPE, especially because phenolic chemicals can sensitize skin and mucosa.
From our vantage on regulatory compliance, PCMC holds approval as a preservative in multiple geographies—Europe, North America, and parts of Asia. Formulators in regulated industries often point to its long safety track record, paired with low typical use concentrations. Nevertheless, growing consumer expectations drive interest in ‘preservative-free’ and ‘natural’ claims. Our regulatory team tracks emerging data and surveillance findings, helping adjust technical data sheets as needed with the realities of evolving hazard classifications and labelling.
For the context of end-product formulation, correct dosing remains paramount. Over-application can provoke skin sensitivity; insufficient dosing leads to microbial breakthrough and spoilage. We help customers by referencing trusted literature, offering direct lab support on determining minimum effective concentrations, and digging up old records from real-world preservative challenge tests. Actual customer feedback informs our recommendations more than anything else.
Working in chemical synthesis, you quickly appreciate that the ‘same’ compound can act very differently based on how it is made. Each improvement we’ve introduced—more efficient chlorination, tighter temperature control, improved crystallization—was born out of resolving actual customer complaints or field failures. We have spent countless hours refining purification steps, often responding to requests for ever-cleaner product or closer lot control.
The journey to low-residue, food/pharma-compliant PCMC was not simple. Our teams learned to wring out even trace levels of chlorinated byproducts, so that finished pharmaceuticals avoid regulatory friction. The investment in additional distillation and recrystallization runs translates into actual cost and time, but we keep at it because finished manufacturers see direct benefit: stable products, less chance of batch failures, and happier regulators.
Technical service ties directly to manufacturing capability. On site, our R&D teams run routine applications testing—mixing creams, gels, and disinfectants under bottling-scale conditions. Production lines run validation batches using actual client processes. By troubleshooting occasional haze or sedimentation events, we close the gap between lab and factory reality. This hands-on, iterative approach means that we help steer customers to the right concentration, solvent choice, and mixing sequence for their filled lines.
Manufacturers want assurance that each box of raw material brings consistent, predictable results. In this market, disruptions and shortages spell real trouble: missed launch dates, recalled batches, shelf-life complaints, and even safety issues. Building resilient supply chains goes hand in hand with stable production management; we have weathered raw material shortages by keeping trusted, audited suppliers and maintaining emergency stock.
Shipping PCMC safely presents lively logistical challenges—phenolics cannot travel with oxidizers and must be kept dry. Our warehouse staff moves pallets into humidity- and temperature-controlled stores within hours of batch release. Each drum is sealed and logged against outflow, with full traceability through inventory management systems designed for rapid recall in the rare event of a non-conforming lot. By running on-site stability studies in parallel with customer reviews, we back up paperwork with practical proof, ensuring uninterrupted access for our partners.
Conversations with downstream packagers and blenders underline the importance of prompt, knowledgeable support. No automated system replaces line-of-sight troubleshooting. We often send technical teams on-site when clients introduce changes to their own processes, observing real-time blending to pre-empt agglomeration, precipitation, or unexpected color changes.
Chemical manufacturing faces real scrutiny on environmental performance. We have reduced solvent waste and improved recovery, keeping effluent within legal discharge limits and reducing the overall footprint of PCMC production. Waste chlorinated compounds, historically a headache, get carefully collected and disposed of by specialist handlers. Every incremental improvement, from reaction yield optimization to emissions capture, has roots in first-hand experience on the shop floor, not just in the lab.
Participating in industry dialogues opens our eyes to where further progress makes sense—waste minimization, greener reagents, safer working processes. Our team actively exchanges knowledge with other manufacturers across the sector. By integrating closed-system transfers, improved dust collection, and digital process monitoring, we actively reduce risks for both workers and the surrounding community.
The conversation on green chemistry continues to evolve. We direct regular R&D budget towards finding renewable feedstocks, evaluating biosynthetic pathways, and optimizing recycling of solvents and process water. Some clients directly request PCMC with carbon footprint declarations; we strive to support this with transparent, audited data from real batch logs and site-level reporting.
Product requirements keep changing. Clients develop new emulsions, switch packaging materials, and respond to trends such as preservative reduction and natural-origin claims. We stay sharp by adapting PCMC grades for specific requirements—offering finer or coarser powders, adjusting packaging options to support automation, and responding to regulations that target trace contaminants. Our open channel with cosmetic and pharmaceutical R&D leaders keeps our product development aligned with shifts in safety standards, market sentiment, and technical needs.
Practical support goes a long way toward building trust. Whether it’s fielding late-night technical calls about a filling line issue or troubleshooting inconsistent dispersion in a new formula, our hands-on chemical specialists combine manufacturing know-how with deep ingredient focus. That connection between plant floor and end product makes the difference for customers seeking more than a commodity chemical.
Ultimately, our work as a chemical manufacturer is defined by responsiveness, control, and direct experience. Our PCMC stands not only on its chemical merits but also on the genuine expertise invested at every stage of its production—from raw material arrival to the final sealed drum. By keeping pace with the realities of formulating, packing, shipping, and regulatory management, we support customers seeking consistent, safe, and proven antimicrobial protection across a world of applications.
