|
HS Code |
749752 |
| Chemicalname | 6-Chloro-O-Cresol |
| Casnumber | 1570-64-5 |
| Molecularformula | C7H7ClO |
| Molecularweight | 142.58 g/mol |
| Appearance | White to off-white crystalline powder |
| Meltingpoint | 64-68°C |
| Boilingpoint | 224°C at 760 mmHg |
| Solubilityinwater | Slightly soluble |
| Density | 1.32 g/cm³ |
| Synonyms | 2-Methyl-6-chlorophenol |
As an accredited 6-Chloro-O-Cresol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | The packaging for 6-Chloro-O-Cresol, 100g, is a sealed amber glass bottle with a tamper-evident screw cap and hazard labeling. |
| Shipping | 6-Chloro-O-Cresol is shipped in tightly sealed containers, away from direct sunlight and incompatible materials. It should be handled with chemical-resistant gloves and transported according to local, national, and international regulations for hazardous materials. The package must be labeled appropriately to ensure safe and compliant handling during transit. |
| Storage | 6-Chloro-O-Cresol should be stored in a tightly sealed container, in a cool, dry, and well-ventilated area. Protect it from direct sunlight, heat, and incompatible substances such as strong oxidizers. Clearly label the container, and keep it away from sources of ignition. Access should be restricted to trained personnel, following standard safety and chemical hygiene procedures. |
Competitive 6-Chloro-O-Cresol prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615380400285
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As a chemical manufacturer invested in every stage of synthesis, quality assurance, and distribution, our approach to 6-Chloro-O-Cresol is grounded in decades of continuous improvement and direct feedback from users across pharmaceutical, agri-chemical, and specialized resin sectors. 6-Chloro-O-Cresol—sometimes referred to by its chemical structure as 6-chloro-2-methylphenol—demands careful handling and exacting process control. Each batch we produce represents more than a routine chemical operation. The manufacturing protocol, raw material sourcing, and purification steps support consistent reliability batch after batch.
Chlorinated cresols stand out among aromatic intermediates for their dual ability to function as preserving agents and building blocks for synthesis. 6-Chloro-O-Cresol emerges from this family with distinct characteristics driven by the position of the methyl and chloro groups on the benzene ring. Our facilities draw on custom-designed reactors and precision-chlorination technologies to pursue near-perfect ortho selectivity, discouraging excessive side product formation.
Years of exploration with catalyst types and chlorination techniques have increased our selectivity well above the industry norm. This is no small task. Even a mild shift in temperature or pH can encourage unwanted isomers or tars. Process engineers at our site monitor every run; automation supports reproducibility, but years at the bench have taught our team where a shift in odor, color, or viscosity can signal the need for closer inspection. Every kilogram reflects thousands of careful adjustments behind the scenes.
Customers in pharma, plastics, and pesticide intermediates have grown tired of supply interruptions caused by variable melting points, poor flow, or hidden impurities that can damage catalyst beds down the line. Our 6-Chloro-O-Cresol exits recrystallization at a tightly controlled melting range, confirmed by differential scanning calorimetry, every shipment. We measure trace water content using Karl Fischer titration, not just standard drying ovens. Each drum is nitrogen blanketed to keep oxidation at bay before closure, a safeguard adopted after consulting with clients who struggled with off-odors due to slow surface degradation.
By isolating the critical isomer and driving total purity levels up, the finished material leaves no ambiguity for downstream formulation. We sample from top, middle, and bottom of packed containers, testing for homogeneity, and monitor for pH drift during storage. This practice evolved out of years of seeing how packaging choices, handling temperatures, and even shipment vibration can shape product stability.
Not all cresolated compounds behave the same way. The activities of ortho, meta, and para isomers diverge sharply in real-world applications, a fact often glossed over in procurement conversations. The 6-chloro derivative delivers strong antimicrobial power and stability in alkaline and neutral systems, unlike some analogues which hydrolyze or yellow quickly. We have observed, in plant, that shifting just one substitution to the meta position raises byproduct levels and introduces persistent trace contaminants.
For resin and polymer producers, the melting range and low volatility of our 6-Chloro-O-Cresol support higher throughput on extruders and minimize off-gassing, reducing worker exposure compared to more volatile cresols. In pharmaceutical synthesis, selectivity matters above all. Trace non-target isomers can inhibit downstream steps, creating new isolation headaches or regulatory headaches if they slip undetected into the finished API. By targeting the ortho form, with strong analytical controls at every stage, we mitigate regulatory review risks and ensure lot-to-lot reproducibility.
6-Chloro-O-Cresol’s most frequent journey begins as a preservative or disinfectant. Over years of direct engagement with formulators in personal care and topical pharmaceutical products, we saw requests for lower free phenol content. These insights led us to refine washing protocols in the mother liquor stage, removing potential irritants while sustaining preservation activity. We respond to questions about formulation by running stability trials onsite, replicating pH and ionic strengths observed out in the field.
Agricultural chemistries employ 6-Chloro-O-Cresol as a key intermediate for some herbicide and insecticide actives. Universally, the demand from these blenders comes down to two pain points: batch color shift, which can indicate thermal decomposition, and minute differences in chlorine substitution patterns impacting bioactivity. By documenting every batch’s TLC and GC trace, and banking reference samples, we put knowledge into the hands of end users, allowing them to spot-substitute or troubleshoot with confidence.
Industrial resin and coating customers prize our product’s lower sodium and sulfate content, a direct outcome of water source changes and multi-step washing protocols. In resins, even parts-per-million shifts in ionic content can destabilize emulsions or cause faults in high-gloss finishes. Working in step with technologists, our manufacturing program focuses on combining high throughput with the finesse needed for these precision-driven users.
Over the years, we have seen competitors struggle to limit byproduct formation, particularly in high-throughput plants lacking inline monitoring. The result is often a product with a wider impurity profile, failing to meet the strict needs of regulated markets. Granular control over process conditions, and intentional slow-downs during key reaction steps, have been the markers of our approach since inception.
Packaging emerged as another source of quality differences, especially for cresol derivatives sensitive to oxygen and moisture. Early on, we adopted high-barrier liners, followed by triple-seal closures, drawing from customer reports of caking, color drift, or surface crusting during long-haul export. Each improvement was more a form of problem-solving than value-adding sales talk. Trial drum shipments rode in real containers on real trade routes, with analysis performed at the receiving end, not just the sending port.
We have worked closely with waste processors to ensure that residuals and byproducts, rich in phenolic value, are returned to upstream processes or safely neutralized. Many customers today ask about our approach to circular solutions and closed-loop production, and our experience running solvent recovery and chlorinated effluent scrubbers shapes both cost management and long-term sustainability.
Working with 6-Chloro-O-Cresol across international markets means living in a world of shifting compliance needs: REACH, TSCA, K-REACH, and varying pesticide active substance lists all change regularly. Clients repeatedly seek input not just on certificates of analysis but on original batch records and traceability. To support audits and customer compliance checks, we maintain digital archives linking raw material lots to final batch shipments, streamlining the due diligence work for everyone involved.
Adverse events tied to excipient impurities or unknown isomer mixes prompted us to develop enhanced purity verification tailored to the needs of pharmaceutical GMP—a decision that followed direct partnership with inspectors. LIMS protocols, trace impurity flags, and recall drills keep us ready for regulatory spot-checks.
Making 6-Chloro-O-Cresol consistently starts long before the first flask sees feedstock chlorotoluenes. We start each production run by validating the purity of incoming raw materials, drawing on relationships with upstream chemical partners nurtured across many years. Each delivery is stress-tested for outlier contaminants that can arise from new manufacturing lots at the supplier’s end.
Our plant team performs most spectroscopy and chromatography in-house. HPLC and GC-MS, run daily, provide the fine detail needed to separate the true 6-chloro fraction from structurally similar contaminants. In the event of outlier readings, an intensely collaborative root cause review unfolds, sometimes involving modifications to reactor agitation speed or even supplier process changes. These feedback channels support critical thinking and continual learning among shop floor teams, not just management.
Production of chlorinated aromatics presents real safety risks, from vapor exposure and static discharge to accidental mixing of incompatible materials. Our investment in advanced air handling, ground-level spill containment, and real-time process monitoring balances volume with human safety. The manufacturing zone includes multiple containment barriers and vapor scrubbing capacity built for scale. Sampling equipment is specified to avoid introducing even trace metals or fibers, minimizing risks to both product and personnel.
By sharing lessons learned from near-misses and ongoing risk assessments, the workforce owns the culture of vigilance vital to running this type of synthesis. Feedback loops between operators and technical managers help close the gap between SOPs on paper and the realities of temperature, pressure, and human judgment on the line.
Over the years we have received direct feedback from long-term partners in drug formulation and resin blending. Stability in melt flow, even under variable ambient humidity, tracks directly to the controlled crystal habit produced here. One early adopter working in veterinary disinfectants observed that product delivered at elevated temperature sealed in moisture from ambient air. In response, standard operating procedures switched to a two-step drum cooling system before final packaging, a subtle fix that paid off by preventing downstream hydrolysis.
In recent years, echoing concerns over microimpurities, analytical teams at several multinational clients requested reports on trace halogenated species not covered by local compendia. Responding to these requests, we invested in more sensitive ion chromatography systems and upgraded calibration reference standards. This deep-level transparency on batch analytics reflects a shared commitment not just to minimum compliance but to risk prevention.
As an integrated manufacturer, we keep communication channels open at every step of the order cycle. Whether it involves sharing technical test methods, arranging custom packaging to fit rare dispensing equipment, or providing input for new regulatory dossiers, the approach stays collaborative. Regular plant tours—virtual or in-person—help build trust and allow users to see filtration, drying, and packaging work in real-world motion. These initiatives help customers and partners not only verify quality but understand the context and reasoning behind each manufacturing decision.
Crafting each batch of 6-Chloro-O-Cresol means working at the intersection of chemistry, process engineering, regulation, and true hands-on experience. Key improvements—whether perfected chlorination, smarter packaging, or finer impurity analytics—trace directly to lessons learned working shoulder-to-shoulder with industry partners and regulatory teams. This product reflects cumulative learning, rigorous process discipline, and an open approach to challenges both expected and unforeseen.
Every step aims at keeping the supply chain resilient, transparent, and effective from our plant to your formulation room. Trust built over decades flows into each drum or pallet. Feedback is always encouraged; every question is an opportunity to strengthen the bond between maker and user. Our 6-Chloro-O-Cresol supports innovators, producers, and formulators who value reliability and the benefits of direct, expert-driven manufacturing.
