2,3,6-Trimethylphenol, also known by its molecular formula C9H12O, belongs to the class of methylated phenols, finding use across a range of industrial and chemical applications. This compound appears in forms like flakes, fine powders, pearlescent solids, and sometimes as larger crystalline material. Its unique structure features a benzene ring substituted by three methyl groups at the 2, 3, and 6 positions, with a hydroxyl group directly attached to the aromatic core. Given its specific chemical design, this substance delivers a set of physical and reactive behaviors that set it apart from other methylphenol variants.
Many recognize 2,3,6-Trimethylphenol by its white to pale yellow solid appearance at room temperature. In laboratory settings, handling often reveals its crystalline form, but suppliers may offer it as granules, flakes, or fine powders depending on storage method or transport requirements. Typical melting point sits close to 62-65°C, while the boiling point extends above 240°C. This phenolic compound has a molecular weight of 136.19 g/mol, a fact that matters in every quantitative chemical process. Its density lands around 1.04 g/cm³, so it’s noticeably less dense than water, which influences storage and solution preparation.
Molecular formula C9H12O tells only part of the story. The structure itself, consisting of a phenol ring attached to methyl groups at positions 2, 3, and 6, impacts both reactivity and solubility. The presence and location of these methyl groups shield the hydroxyl hydrogen, slightly suppressing acidity compared to simpler phenols and changing interaction patterns with other organic or inorganic reagents. This unique framework can be confirmed through analytical methods like NMR, infrared spectroscopy, or mass spectrometry — tools commonly used in both raw materials validation and finished quality assessment.
Regulatory and trade protocols commonly list 2,3,6-Trimethylphenol under HS Code 290719, with specific subcategories depending on purity and intended use. In chemical manufacturing, the compound often acts as a key intermediate or raw material for synthesizing specialized antioxidants, agrochemicals, and certain resins. Materials scientists and industrial chemists value this compound for its targeted reactivity and predictable behavior in multi-step reactions. Its properties encourage efficient yields and minimal byproduct formation in experienced hands.
Though 2,3,6-Trimethylphenol serves a critical industrial function, its phenolic nature means caution is always required during storage, handling, and use. As a solid or in solution, contact with skin or mucous membranes can cause irritation, and inhaling fine powder or aerosol releases could lead to respiratory discomfort. Safe practice dictates use of gloves, well-ventilated environments, and protective eyewear. Chemists tracking and containing volatile organics understand the risk profile tied to phenolic compounds — flammability, potential toxicity on sustained exposure, risk of environmental release. Disposal of waste or off-spec batches falls under hazardous chemical protocols, so labeling, containment, and certified waste management all matter. Emergency measures, like eyewash stations and chemical spill kits, stand by in every well-equipped facility using or producing this compound.
Having worked on several projects involving methylated phenols, one thing stands out: every production step, from sourcing raw material to downstream processing, depends on receiving material that matches published specifications. Whether it arrives as a powder, crystalline chunk, or compact pearl, texture and color sometimes point to subtle quality differences or the presence of trace impurities. Verifying density, melting point, and spectral data protects both product safety and plant efficiency, especially for chemical manufacturing runs with small margins for error. Regulatory compliance with trade codes, waste handling, and workplace safety protocols also separates responsible suppliers from risky ones. Experience drives home the value of up-to-date safety data sheets, transparent chemical traceability, and clear communication between sourcing, quality teams, and process engineers.
