Product Name: Tert-Butylhydroquinone
Synonyms: TBHQ, 2-(1,1-Dimethylethyl)-1,4-benzenediol
Chemical Family: Phenolic antioxidant
CAS Number: 1948-33-0
Recommended Use: Food preservative, antioxidant in fats and oils, industrial stabilizer
Manufacturer Information: (Include address, emergency contact, phone for additional data, email for inquiries)
Classification: Eye irritation category 2A, Skin irritation category 2, Specific target organ toxicity following single exposure category 3
GHS Label Elements: Warning symbol (exclamation mark), hazard codes H315, H319, H335
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: Wash hands after handling, wear protective gloves/eye protection, avoid breathing dust or vapors, use only outdoors or in a well-ventilated area
Other Hazards: Combustible powder, dust explosion hazard possible in fine particulate form
Chemical Name: Tert-Butylhydroquinone
Common Name/Synonyms: TBHQ
Chemical Formula: C10H14O2
Concentration: ≥ 99%
Impurities: Trace hydroquinone, water, other phenolic compounds (low concentration, typically <1%)
Eye Contact: Flush eyes gently with running water for 15 minutes, remove contact lenses if present, seek immediate medical advice
Skin Contact: Wash affected area with soap and water, remove contaminated clothing, seek medical attention if skin irritation persists
Inhalation: Remove person to fresh air, provide oxygen if breathing is difficult, contact a doctor if symptoms continue
Ingestion: Rinse mouth with water, avoid inducing vomiting, give plenty of water if conscious, contact poison control and seek medical guidance
Symptoms: Redness, irritation, coughing, shortness of breath, headache, stomach upset
Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Unsuitable Extinguishing Media: Direct water streams on burning powder or dust could disperse and intensify flames
Special Hazards: Fine dust may form explosive mixtures with air, hazardous carbon oxides and smoke produced during combustion
Protective Equipment: Self-contained breathing apparatus (SCBA), fire-resistant clothing recommended
Firefighting Instructions: Approach from upwind, avoid inhalation of smoke or fumes, cool containers exposed to fire with water spray
Personal Precautions: Use protective equipment (respirator, gloves, goggles), evacuate area, avoid breathing dust
Environmental Precautions: Prevent entry into drains or waterways, contain spill to minimize contamination
Containment and Cleanup: Sweep or vacuum up material with explosion-proof equipment, transfer to a suitable, labeled disposal container
Decontamination: Wash contaminated surfaces with water and detergent, ventilate area before reentry
Safe Handling: Handle in well-ventilated areas, use local exhaust if needed, avoid creating dust clouds, do not get in eyes or on skin
Hygiene Recommendations: Wash hands before eating, drinking, or using restroom, prevent ingestion and inhalation exposure
Storage Conditions: Store in tightly closed containers in a cool, dry, and well-ventilated area, keep away from heat sources, ignition points, and incompatible materials
Incompatibilities: Strong oxidizing agents, acids, bases
Packaging Requirements: Corrosion-resistant packaging, labeled with hazard information
Occupational Exposure Limits: No OSHA PEL set; nuisance dust limit 10 mg/m3 (total), 3 mg/m3 (respirable, ACGIH)
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne dust below exposure limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), safety goggles or face shield, lab coat or apron, NIOSH-approved dust respirator for dusty operations
Other: Emergency eyewash and safety shower in immediate work area
Appearance: White crystalline powder
Odor: Slight, characteristic phenolic odor
Odor Threshold: Not established
pH: Not applicable in solid state
Melting Point: 126–129°C
Boiling Point: 273°C (decomposes)
Flash Point: 150°C (closed cup)
Evaporation Rate: Not applicable
Flammability: Combustible in powder form
Explosion Limits: Not determined; dust explosion risk present
Vapor Pressure: <0.01 mm Hg at 20°C
Vapor Density: Not applicable
Density: 1.05 g/cm3 (solid)
Solubility: Soluble in alcohols, oils, slightly water-soluble
Partition coefficient (log Kow): About 1.4
Decomposition Temperature: Above 273°C
Viscosity: Not applicable
Molecular Weight: 166.22 g/mol
Chemical Stability: Stable under recommended storage and handling, light sensitive
Reactivity: No known dangerous reactivity under normal use
Conditions to Avoid: Exposure to heat, open flames, sparks, direct sunlight, strong oxidizing conditions
Incompatible Materials: Strong oxidizers such as peroxides, nitric acid, strong bases, strong acids
Decomposition Products: Carbon monoxide, carbon dioxide, phenolic derivatives, hydrocarbons
Hazardous Polymerization: Does not occur under normal conditions
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): 1260 mg/kg
Chronic Toxicity: Prolonged exposure may cause skin or respiratory sensitization or irritation
Health Effects: Eye, skin, and respiratory tract irritation, headache, nausea at high doses
Carcinogenicity: Not classified as human carcinogen by IARC, NTP, or OSHA
Mutagenicity & Reproductive Toxicity: Negative in most tests; high doses in animals can affect liver, kidney
Signs and Symptoms: Coughing, burning sensation, redness, chemical burns
Ecotoxicity: Harmful to aquatic life in high concentrations; LC50 (fish): 0.3–1 mg/L (96 hours)
Persistence & Degradability: Moderate persistence; slow biodegradation in soil and water
Bioaccumulative Potential: Low (log Kow indicates moderate potential)
Mobility in Soil: Low to moderate, binds to organic matter
Other Adverse Effects: Can disrupt microbial life in wastewater treatment if concentrations are elevated, not considered a persistent organic pollutant
Precautions: Prevent release into surface water, sewer systems
Waste Treatment Methods: Dispose in accordance with local, regional, national, and international regulations by licensed waste disposal service
Product Disposal: Incinerate at approved facility, avoid landfill disposal if possible
Contaminated Packaging: Rinse well before disposal or send for professional cleaning, then recycle or dispose of according to regulations
Special Instructions: Do not discharge into drains, soil, or water bodies
UN Number: Not regulated as a hazardous material by DOT, IATA, or IMDG
Proper Shipping Name: Tert-Butylhydroquinone
Hazard Class: Not classified
Packing Group: Not assigned
Marine Pollutant: No specific designation
Special Transport Precautions: Avoid releases of dust, keep packaging intact, label shipment clearly
OSHA Status: Non-hazardous under OSHA Hazard Communication Standard
SARA 313: Not listed
TSCA Inventory: Listed
REACH Registration: Pre-registered/registered in Europe
California Proposition 65: Not listed
Other National Regulations: Subject to workplace chemical safety control in multiple jurisdictions
Workplace Labelling: Mark containers with hazard pictogram, chemical name, key precautionary phrases
