Product Name: Resorcinarene
Chemical Name: 1,3-Benzendiol, polymer with formaldehyde
Synonyms: Calix[4]resorcinarene, C-methyl resorcinarene, Tetrahydroxycalix[4]arene
CAS Number: 57450-90-7
Recommended Use: Laboratory chemical, research reagent, host-guest chemistry studies
Restrictions: Not intended for drug, household, or human consumption use
Supplier Info: Address and contact information for supplier provided on container or accompanying paperwork
Classification: Not listed as hazardous by GHS classification, but may cause irritation on contact
Health Hazards: Eye irritation, skin irritation, respiratory tract irritation possible upon direct exposure
Environmental Hazards: Limited data, but persistent in environment not anticipated; avoid release into waterways
Pictogram: Exclamation mark (for irritation)
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; inhalation may lead to respiratory tract discomfort
Precautionary Statements: Prevent dust generation, wear protective clothing, avoid contact with skin and eyes, use only in well-ventilated areas
Chemical: Resorcinarene
CAS Number: 57450-90-7
EC Number: Not assigned
Concentration: 100%, pure substance in this application
Impurities: Trace residual solvents or water may be present; less than 0.5%
Eye Contact: Immediately rinse with copious water for at least 15 minutes; remove contact lenses if present
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing and launder before reuse
Inhalation: Move person to fresh air; seek medical attention if symptoms such as cough or difficulty breathing persist
Ingestion: Rinse mouth with water; never attempt to induce vomiting; seek medical advice if person feels unwell
Most Important Symptoms: Redness, irritation, burning sensation for eyes, skin, and throat; immediate supportive care recommended
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam
Special Hazards: Product may burn and emit irritating fumes including carbon monoxide and carbon dioxide
Advice for Firefighters: Use self-contained breathing apparatus and full protective equipment
Firefighting Procedures: Prevent runoff from firefighting from entering drains or waterways; cool exposed sealed containers with water spray to reduce risk of rupture
Personal Precautions: Ventilate area; avoid dust formation; use recommended personal protective equipment (gloves, goggles, mask)
Environmental Precautions: Prevent material from entering soil, storm drains, septic systems, or natural water sources
Cleanup Methods: Sweep up and transfer to a labeled waste container; avoid raising dust; wash spill site after material pickup is complete
Handling: Wear gloves, protective eyewear, laboratory coat; minimize generation of dust or powder; avoid direct contact and inhalation; use fume hood or local exhaust if available
Storage: Store in tightly sealed containers in a cool, dry, and well-ventilated area; protect from heat, direct sunlight, moisture, and incompatible materials like strong oxidizers
Incompatibilities: Avoid reaction with strong acids, bases, and oxidizing agents, which could degrade product or cause hazardous reactions
Exposure Limits: No established OSHA or ACGIH exposure limits for resorcinarene
Engineering Controls: Work in fume hood or with local exhaust ventilation to minimize airborne dust
Personal Protective Equipment: Use chemical-resistant gloves (e.g., nitrile), safety goggles, lab coat, and respirator if dust is generated in appreciable quantities
Hygiene Measures: Wash hands thoroughly after handling; prohibit eating, drinking, or smoking in work area
Appearance: Off-white to pale yellow crystalline powder
Odor: Odorless or slightly phenolic
Molecular Formula: C28H24O8 (base molecule)
Molecular Weight: ~488 g/mol
Melting Point: 273–275°C (literature values depend on substituents)
Boiling Point: Not applicable; product decomposes before boiling
Solubility: Insoluble in water; soluble in most organic solvents (acetone, methanol, DMSO)
pH: Not established
Vapor Pressure: Not volatile
Density: Approx. 1.35 g/cm³
Flash Point: Not flammable under normal conditions
Chemical Stability: Stable at ambient temperature and pressure under recommended storage conditions
Conditions to Avoid: Prolonged exposure to moisture, direct light, excessive heat
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phenolic derivatives upon thermal decomposition
Polymerization: Not known to undergo hazardous polymerization
Acute Toxicity: No adequate animal or human data available; analogues suggest low acute toxicity
Routes of Exposure: Eyes, skin, inhalation of dust, ingestion
Symptoms: Irritation to skin, eyes, and respiratory tract; may cause temporary discomfort
Chronic Effects: Repeated or prolonged exposure not extensively studied; no evidence of mutagenicity or carcinogenicity reported from available data
Sensitization: Not known to cause allergic reactions
Additional Info: Practice good laboratory hygiene and safety
Ecotoxicity: Data not available; structure suggests limited acute aquatic toxicity, but avoid uncontrolled release
Persistence and Degradability: May persist in environment; slow biodegradation expected based on structure
Bioaccumulation Potential: Not expected to bioaccumulate significantly
Mobility: Non-volatile, insoluble in water, likely to remain in soil or sediment
Other Adverse Effects: Prevent waste discharge into water, soil, or sewage systems
Waste Treatment Methods: Chemical waste must be handled in accordance with local, regional, and national regulations; consult with qualified waste disposal service
Incineration: Permitted if material is not contaminated with incompatible substances
Container Disposal: Triple rinse and dispose of empty containers as hazardous waste or in accordance with approved government guidelines
Precautions: Do not pour into drains, watercourses, or environment
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as a dangerous good for transport
Transport Hazard Class: Non-hazardous
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Ensure containers are well sealed and cushioned to avoid breakage; transport in accordance with carrier requirements for laboratory chemicals
US TSCA Inventory: Not listed
EU REACH Status: Not registered
Canada DSL/NDSL: Not listed
Label Requirements: Label with chemical name, manufacturer, date of preparation, and hazard warnings per GHS
Additional Regulations: Subject to workplace hazard communication standards; comply with local and national safety and environmental regulations for laboratory chemicals
