Boxa Chemical Group Ltd
Knowledge

Material Safety Data Sheet: Protocatechualdehyde

Identification

Product Name: Protocatechualdehyde
Synonyms: 3,4-Dihydroxybenzaldehyde
Chemical Formula: C7H6O3
CAS Number: 139-85-5
Recommended Uses: Laboratory research, pharmaceutical applications, organic synthesis
Manufacturer: List supplier information relevant to your facility
Contact Information: Emergency phone numbers for spills, fire, health hazard reporting
Emergency Overview: Pale-yellow to light brown crystalline solid; distinguishable by aromatic odor

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin sensitization
Label Elements: Pictograms for exclamation mark and health hazard
Signal Word: Warning
Hazard Statements: May cause eye, skin, and respiratory irritation; harmful if swallowed, inhaled, or in contact with skin; may cause allergic skin reaction
Precautionary Statements: Avoid inhalation and contact with eyes or skin; wash hands thoroughly after handling; use personal protective equipment

Composition / Information on Ingredients

Chemical Name: Protocatechualdehyde
Concentration: >99% pure, unless noted otherwise by supplier
Impurities: Trace organic compounds possible depending on synthesis
Molecular Weight: 138.12 g/mol

First Aid Measures

Eye Contact: Flush eyes with water for at least 15 minutes, hold eyelid open, remove contact lenses if present; seek medical help
Skin Contact: Rinse skin with plenty of water, remove contaminated clothing; medical attention in case of reaction
Inhalation: Move person to fresh air, keep at rest, assist breathing; call for medical assistance if symptoms persist
Ingestion: Rinse mouth thoroughly; do not induce vomiting—call poison control or a physician right away

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbondioxide, foam, water spray
Hazardous Combustion Products: Carbon dioxide, carbon monoxide, potentially irritating fumes
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Fire/Explosion Hazards: Combustible solid; dust may form explosive mixtures in air; containers may rupture under fire conditions

Accidental Release Measures

Personal Precautions: Avoid breathing dust, avoid contact with skin or eyes, wear protective clothing including gloves and goggles
Environmental Precautions: Prevent further leakage or spillage if safe; prevent from entering drains or waterways
Containment and Cleanup: Sweep up carefully and collect in suitable containers for disposal; ventilate area; wash contaminated floor with plenty of water

Handling and Storage

Handling: Handle in a well-ventilated area, use personal protective equipment, avoid forming dust, avoid exposure to moisture, keep away from strong oxidizers
Storage: Store in tightly sealed containers, in a cool, dry, and well-ventilated place, away from light and sources of ignition, label containers clearly, restrict access to authorized personnel

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation to maintain airborne levels below recommended limits
Personal Protective Equipment: Wear protective gloves (nitrile, neoprene), chemical-resistant goggles, lab coat, appropriate respiratory protection if dust is generated
Exposure Limits: No established ACGIH, OSHA, or NIOSH exposure limits; use general dust exposure guidance
Hygiene Measures: Do not eat, drink, or smoke while using this product; wash hands before breaks and at the end of work

Physical and Chemical Properties

Appearance: Pale-yellow to light brown crystalline solid
Odor: Faint aromatic
Melting Point: 146-148°C
Boiling Point: Information not readily available, decomposes before boiling
Flash Point: Not determined
Solubility: Soluble in ethanol, ether, slightly soluble in water
Vapor Pressure: Not applicable at standard temperature
Density: 1.334 g/cm³
pH: Not applicable in solid form

Stability and Reactivity

Chemical Stability: Stable under recommended conditions of storage
Conditions to Avoid: Exposure to heat, moisture, light; keep away from oxidizing agents
Incompatible Materials: Strong oxidizers, strong acids
Hazardous Decomposition Products: May produce irritating fumes, carbon monoxide and carbon dioxide if decomposed by heat

Toxicological Information

Routes of Exposure: Ingestion, inhalation, skin and eye contact
Acute Effects: May cause irritation to gastrointestinal tract, mucous membranes, eyes, skin; possible allergic reaction
Chronic Effects: Extended exposure might increase risks of sensitization; no evidence of carcinogenicity found in standard animal models
LD50 (Oral, Rat): Precise value not widely published; likely to exceed 2,000 mg/kg (refer to supplier data)
Symptoms: Redness, watering of eyes, itching, rash, headache, nausea

Ecological Information

Ecotoxicity: Limited data for aquatic toxicity; expected to be harmful in concentrated spills
Persistence and Degradability: Readily biodegradable in soil and water under aerobic conditions
Bioaccumulation Potential: Not expected to bioaccumulate significantly
Mobility in Soil: Will disperse in water; low adsorption to soil particles

Disposal Considerations

Waste Treatment Methods: Dispose of bulk product through licensed chemical disposal facility
Container Disposal: Triple rinse containers before recycling or discarding; do not reuse contaminated packaging
Special Precautions: Follow local, regional, and national hazardous waste regulations; avoid release into environment

Transport Information

UN Number: Not classified as dangerous for transport under most regional guidelines
DOT Classification: Not regulated
Proper Shipping Name: Protocatechualdehyde, chemical substance, solid
Packing Group: Not assigned
Transport Hazards: Ensure packaging prevents dust release and moisture intrusion; inform carriers if transported in large quantities

Regulatory Information

TSCA Status: Listed as a chemical substance in the US Toxic Substances Control Act inventory
REACH Registration: Subject to evaluation under European regulation depending on usage volume
SARA Title III: Substance not listed as a Section 302/304/313 hazardous chemical
Other National Inventories: Verify compliance with country-specific chemical reporting requirements
Label Requirements: Comply with workplace labelling standards: hazard pictograms, signal words, hazard statements