Product Name: Phenol-Glycerol Solution
Chemical Family: Aromatic Alcohol Mixture
Synonyms: Hydroxybenzene-Glycerin Solution
Recommended Use: Laboratory reagent, preservative for biological samples
Manufacturer Information: [Manufacturer Address, Emergency Contact Numbers]
CAS Number (Phenol): 108-95-2
CAS Number (Glycerol): 56-81-5
GHS Classification: Acute toxicity (oral, dermal), Skin corrosion, Serious eye damage, Specific organ toxicity
Signal Word: Danger
Hazard Statements: Harmful if swallowed; Causes severe skin burns and eye damage; May cause respiratory irritation; Toxic if inhaled
Pictograms: Corrosive, Health Hazard, Exclamation Mark
Precautionary Statements: Wear protective clothing, gloves, and eye/face protection; Avoid breathing vapors; Use only outdoors or in well-ventilated areas; Wash thoroughly after handling
Potential Health Effects: Causes burns to skin and eyes; Inhalation may lead to respiratory distress; Ingestion may damage organs
Environmental Hazard: Toxic to aquatic organisms
Component: Phenol
Concentration: 10–60%
CAS Number: 108-95-2
Component: Glycerol
Concentration: 40–90%
CAS Number: 56-81-5
Impurities: Trace water, minimal organic contaminants possible
Inhalation: Immediately remove affected person to fresh air; seek medical attention immediately if symptoms persist or worsen.
Skin Contact: Remove contaminated clothing; rinse skin thoroughly with soap and water for at least 15 minutes; call a physician.
Eye Contact: Immediately flush eyes with running water for at least 15 minutes, lifting upper and lower lids occasionally; call an ophthalmologist.
Ingestion: Seek urgent medical attention; rinse mouth with water; do not induce vomiting unless directed by medical personnel; keep airway clear.
Notes for Physicians: Treat as chemical poisoning; monitor for systemic effects of phenol.
Suitable Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical, water spray
Fire Hazards: Phenol vapors may form explosive mixtures with air; containers may explode from heat exposure
Protective Equipment for Firefighters: Self-contained breathing apparatus (SCBA), full protective suit, chemical-resistant boots
Hazardous Combustion Products: Phenol vapors, carbon monoxide, carbon dioxide, irritant fumes
Firefighting Procedure: Cool exposed containers with water; avoid breathing vapors or fumes; evacuate area as needed
Personal Precautions: Wear chemical-resistant gloves, protective clothing, face shield, proper ventilation
Environmental Precautions: Prevent further leakage or spillage; do not allow material to reach drains or water sources
Cleanup Methods: Absorb with inert material (vermiculite, sand); sweep up and place in suitable containers; wash area with dilute sodium bicarbonate solution
Disposal: Follow local regulations for hazardous chemical disposal; label waste containers accurately
Handling: Handle in fume hood; wear appropriate personal protective equipment at all times; avoid inhalation, ingestion, skin or eye contact; use non-sparking tools
Storage: Store in tightly closed, corrosion-resistant container; keep in cool, ventilated, dry area away from oxidizers, strong acids, metal powders
Special Requirements: Segregate from incompatible substances; routinely check containers for signs of corrosion or leakage
Occupational Exposure Limits (Phenol): ACGIH TLV: 5 ppm; OSHA PEL: 5 ppm
Exposure Controls: Use laboratory fume hood; install explosion-proof ventilation; maintain eyewash stations and safety showers
Personal Protective Equipment (PPE): Chemical splash goggles, face shield, resistant gloves (nitrile, neoprene), full-length lab coat, respiratory protection if ventilatory controls are inadequate
Hygiene Measures: Wash hands and exposed skin thoroughly after use; do not eat, drink, or smoke during handling
Appearance: Clear, colorless to pale pink liquid
Odor: Phenolic, sweet odor
pH: Slightly acidic
Boiling Point (Mixture): 185 – 205°C
Melting/Freezing Point: < 10°C, depending on proportion
Flash Point: 79°C (phenol)
Specific Gravity: 1.1 – 1.2
Solubility: Soluble in water, ethanol; miscible with many organics
Vapor Pressure: Moderate
Viscosity: Viscous due to glycerol
Partition Coefficient (log Kow): Phenol: 1.5, Glycerol: -1.76
Chemical Stability: Normally stable under recommended storage and handling conditions
Reactivity: Reacts with strong oxidizers, acids, anhydrides, chlorinating agents
Hazardous Reactions: Emits toxic fumes when heated or combusted; incompatible with strong bases and metals
Decomposition Products: Phenol vapors, benzene, formaldehyde, carbon monoxide/dioxide
Conditions to Avoid: Excess heat, open flame, incompatible substances, direct sunlight
Acute Toxicity: Phenol LD50 (oral, rat): 340 mg/kg; Glycerol LD50 (oral, rat): 12,600 mg/kg
Chronic Effects: May cause systemic poisoning, affects central nervous system, kidney, liver with prolonged exposure
Routes of Exposure: Inhalation, dermal, ocular, ingestion
Symptoms: Burns, dizziness, sweating, nausea, respiratory distress, shock
Carcinogenicity: Phenol not classified as carcinogen by IARC; insufficient evidence for glycerol
Mutagenicity & Teratogenicity: Data for phenol indicate potential mutagenicity; glycerol rated low hazard
Eco-toxicity: Phenol highly toxic to aquatic life
Persistence and Degradability: Phenol biodegrades but can accumulate in water and soil before breakdown; glycerol readily degrades
Bioaccumulation Potential: Low for both ingredients
Mobility in Soil: Phenol moderately mobile in soil; glycerol high mobility
Other Hazards: Avoid uncontrolled environmental release; contamination can lead to large-scale aquatic toxicity
Disposal Methods: Dispose of through licensed chemical waste contractor; incinerate in compliance with local, state, and federal regulations
Contaminated Packaging: Treat empty containers as hazardous waste; triple rinse and puncture before disposal
Precautions: Never discharge into drains, waterways, or on ground; segregate from municipal waste streams
UN Number: UN1671
Proper Shipping Name: Phenol Solution
Transport Hazard Class: 6.1 (Toxic substance)
Packing Group: II
Label: Toxic, Corrosive
Special Transport Precautions: Containers secure, upright, adequately labeled; emergency response kit recommended for transport vehicles; follow national and international regulations for hazardous material transport
U.S. Regulations: Phenol listed under SARA Title III, CERCLA reportable quantities apply; both chemicals appear on TSCA inventory
EU Classification: EC Index No. 604-001-00-2; GHS/CLP compliant labeling required
Workplace Safety: Follow OSHA, ACGIH, NIOSH exposure limits
Lab Use: Controlled under chemical hygiene plans and laboratory safety standards
Other International Regulations: Compliant with WHMIS (Canada), GHS (UN), and REACH (EU) as applicable
