Product Name: O-Cresol
Chemical Name: 2-Methylphenol
CAS Number: 95-48-7
Synonyms: ortho-Cresol, 2-Hydroxytoluene
Recommended Use: Chemical intermediate, Disinfectants, Solvent, Resins and dyes manufacturing
Supplier Information: Manufacturer and distributor contact details, including address and emergency phone numbers
Emergency Contact: Fire department, poison control center or local emergency service numbers
UN Number: 2076
Molecular Formula: C7H8O
Molecular Weight: 108.14 g/mol
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation) Category 3, Skin Corrosion/Irritation Category 1B, Serious Eye Damage/Irritation Category 1, Specific Target Organ Toxicity (Single Exposure) Category 3
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin or inhaled; causes severe skin burns and eye damage; may cause respiratory irritation
Pictograms: Skull and crossbones, Corrosion, Exclamation mark
Precautionary Statements: Avoid breathing dust/vapors; use only outdoors or in a well-ventilated area; wear protective gloves/clothing/eye/face protection; wash exposed skin thoroughly after handling
Other Hazards: May cause central nervous system depression, kidneys and liver toxicity, harmful to aquatic life
Chemical: O-Cresol
Common Name: 2-Methylphenol
Concentration: ≥99%
CAS Number: 95-48-7
Impurities: Trace phenols, nonhazardous stabilizers (if present, supplier-specific)
Inhalation: Move victim to fresh air; keep at rest; seek immediate medical attention if symptoms like coughing or difficulty breathing develop; provide oxygen if breathing becomes difficult
Skin Contact: Remove contaminated clothing immediately; rinse skin thoroughly with running water for at least 15 minutes; get medical attention as soon as possible; do not attempt to neutralize with chemicals
Eye Contact: Rinse cautiously with water for several minutes; remove contact lenses if present and easy to do; continue rinsing for at least 15 minutes; seek urgent medical attention
Ingestion: Do not induce vomiting; rinse mouth; drink water if conscious; never give anything by mouth to an unconscious person; seek emergency medical help without delay
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide (CO2), water spray (use protective shielding for water)
Unsuitable Extinguishing Media: Direct water jet as it may spread the product
Hazardous Combustion Products: Toxic fumes such as carbon monoxide, carbon dioxide, and phenolic vapors
Protective Equipment: Full protective gear required, including self-contained breathing apparatus (SCBA)
Special Precautions: Fight fire from a safe distance; avoid inhalation of decomposition products; containers may explode in heat; remove unaffected containers if it can be done safely
Personal Precautions: Evacuate personnel to safe areas; use personal protective equipment; keep unnecessary people away
Environmental Precautions: Prevent further leakage or spillage; do not let product enter drains, watercourses, or soil
Methods for Containment: Stop leak if safe to do so; contain and collect spillage with inert absorbent material (sand, earth, vermiculite)
Cleanup Procedures: Place absorbed material in labeled containers for disposal according to local regulations; clean contaminated surfaces thoroughly; ventilate the area; wash spill site after material pickup
Precautions for Handling: Wear personal protective gear; handle only in well-ventilated areas; avoid contact with skin, eyes, and clothing; do not breathe vapors or mist
Safe Storage Conditions: Store in a tightly closed container in a cool, dry, and well-ventilated place; keep away from heat sources, sparks, and open flames; store separately from oxidizing agents, acids, and bases; segregate from food and drink
Recommended Packaging Materials: Use containers made of compatible materials like polyethylene or stainless steel
Other Advice: Practice good housekeeping; keep away from children and unauthorized personnel
Control Parameters: Occupational exposure limit (OEL): ACGIH TLV 5 ppm (skin); OSHA PEL 5 ppm (skin)
Engineering Controls: Use local exhaust or general dilution ventilation to maintain airborne levels below exposure limits
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene); tightly sealed safety goggles and face shield; flame-retardant lab coat; suitable respiratory protection (air-purifying respirator with organic vapor cartridge)
Hygiene Measures: Wash hands thoroughly before breaks and after handling; separate contaminated clothing and wash before reuse; eye wash station and emergency shower must be accessible
Environmental Controls: Monitor to prevent environmental release; use containment methods when transferring or mixing
Appearance: Colorless to pale yellow liquid or solid (crystals) at room temperature
Odor: Distinct phenolic odor, sharp and medicinal
Odor Threshold: 0.1–0.5 ppm
pH: Weakly acidic
Melting Point: 28–31°C (82–88°F)
Boiling Point: 191–192°C (376–378°F)
Flash Point: 81°C (178°F), closed cup
Evaporation Rate: Slow
Flammability: Combustible at room temperature
Vapor Pressure: 0.2 mm Hg at 25°C
Vapor Density: 3.7 (air = 1)
Solubility: Moderately soluble in water, soluble in ethanol and ether
Partition Coefficient (log Kow): 1.95
Auto-Ignition Temperature: 555°C (1031°F)
Decomposition Temperature: Not specified
Viscosity: Not specified
Chemical Stability: Stable under standard temperature and pressure conditions
Reactivity: May react vigorously with strong oxidizing agents
Conditions to Avoid: Heat, sparks, open flames, sources of ignition, strong acids, strong bases, direct sunlight
Incompatible Materials: Oxidizers (e.g., nitric acid), strong acids (e.g., sulfuric acid), chlorinating agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phenolic compounds
Polymerization: Does not occur under normal handling and storage
Routes of Exposure: Skin absorption, inhalation, ingestion, eye contact
Acute Toxicity: Oral LD50 (rat) 121 mg/kg; Dermal LD50 (rabbit) 890 mg/kg
Chronic Effects: May cause dermatitis, central nervous system depression, liver and kidney damage after repeated exposure
Symptoms of Exposure: Burning sensation, coughing, shortness of breath, headache, nausea, vomiting, abdominal pain, drowsiness, convulsions, unconsciousness in severe cases
Corrosive/Irritant Properties: Causes severe skin burns and eye damage; toxic by skin absorption
Other Risks: Data indicates possible mutagenic effects in animal tests; not listed as carcinogenic by IARC, OSHA, NTP
Aquatic Toxicity: Toxic to aquatic organisms; LC50 (fish, 96 h): 35.1 mg/L
Persistence and Degradability: Biodegradable but may persist in water or soil under certain conditions
Bioaccumulative Potential: Low to moderate, log Kow 1.95
Mobility in Soil: Moderately mobile; can leach through soil to groundwater
Other Adverse Effects: Dangerous to aquatic plants and invertebrates, even at low concentrations; large spills can disrupt microbial communities in soil and water
Disposal Methods: Dispose of product and contaminated packaging via licensed hazardous waste disposal contractor; incineration recommended under controlled conditions
Contaminated Packaging: Triple rinse with suitable solvent; dispose of rinsate safely; containers should not be reused
European Waste Catalogue (EWC) Code: 07 01 08 (pharmaceutical and chemical waste)
Additional Guidance: Comply with federal, state, and local regulations; do not discharge to sewers or natural water bodies
Precautions: Notify relevant environmental authorities in case of large-scale release impacting environment
UN Number: 2076
Proper Shipping Name: Cresols
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Labels Required: Toxic
Environmental Hazards: Marine pollutant
Special Transport Precautions: Store and transport in upright, tightly sealed containers away from sources of ignition and oxidizing agents; ensure clear labeling and documentation
Applicable Regulations: IMDG, IATA, ADR compliant; notify transport authorities before moving large quantities
OSHA Classification: Hazardous chemical; covered under Hazard Communication Standard (29 CFR 1910.1200)
TSCA Status: Listed
SARA 313: Subject to reporting; o-cresol listed as a toxic chemical
RCRA Status: Classified as hazardous waste (U052)
CERCLA Reportable Quantity (RQ): 100 lbs (45.4 kg)
WHMIS Classification (Canada): Class D1B (Toxic), Class E (Corrosive material)
EU Classification: Xn (Harmful), C (Corrosive), N (Dangerous for the environment); R-phrases and S-phrases apply
REACH Registration: Registered under REACH; use restricted in some applications
Other Regulations: Subject to local, state, and international handling and use restrictions; always check the latest requirements for your region
