Product Name: Isopropyl Cresols
Chemical Family: Alkylphenols
Molecular Formula: C10H14O
Synonyms: o-cresol isomers, 2-isopropyl-5-methylphenol, IPC
CAS Numbers: 88-69-7 (o-isopropyl cresol), 3228-02-2 (m-isopropyl cresol), 100-06-1 (p-isopropyl cresol)
Recommended Use: Industrial chemical, antiseptic, disinfectant, raw material in chemical synthesis
Supplier: Commercial and chemical-grade manufacturers
Emergency Telephone: Refer to local emergency contact
Classification: Flammable liquid; Irritant; Harmful if inhaled or swallowed
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation, may cause allergy, harmful if inhaled or ingested, may cause respiratory tract irritation, flammable liquids and vapors
Pictograms: Flame, Exclamation Mark
Precautionary Statements: Keep away from heat and ignition sources, avoid breathing vapors, wash hands thoroughly after handling, use only in well-ventilated areas, wear personal protective equipment
Chemical Name: Isopropyl Cresols
Concentration: Typically > 98% pure; trace impurities may include other cresol isomers
CAS Numbers: See above in Identification
Impurities: Not expected to add significant additional hazards, but manufacturing grade may contain phenol derivatives or small solvent residues
Eye Contact: Flush with water for at least 15 minutes, remove contact lenses, seek medical help
Skin Contact: Wash with soap and plenty of water, remove contaminated clothing, get medical attention for persistent irritation
Inhalation: Move person to fresh air, if symptoms persist get medical attention
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, call poison center or doctor
General Advice: Show MSDS to medical personnel; provide symptom-focused treatment
Suitable Extinguishing Media: Foam, dry chemical, CO2, water spray
Unsuitable Media: Use water jet only for cooling surfaces
Special Hazards: Produces toxic fumes of carbon monoxide, carbon dioxide, phenolic vapors
Protective Equipment: Wear full protective clothing and self-contained breathing apparatus
Firefighting Instructions: Cool tanks with water spray, prevent runoff to water systems, evacuate area if necessary
Personal Precautions: Evacuate area, ventilate, avoid contact with skin and eyes, wear proper PPE
Environmental Precautions: Prevent release to soil, sewers, drains
Spill Cleanup: Absorb with inert material (sand, earth, vermiculite), collect into containers for disposal, thoroughly ventilate area
Disposal: Follow local regulations for hazardous waste disposal
Handling: Use only with adequate ventilation, avoid inhalation of vapors, avoid direct contact with product, do not eat or drink when handling
Storage Conditions: Keep in tightly closed container, store in cool, dry, well-ventilated place away from heat, sparks, open flame, and incompatible materials (oxidizers, acids)
Incompatibilities: Strong acids, bases, oxidizing agents
Exposure Limits: No specific OSHA or ACGIH TLV established; minimize exposure as cresols in general have workplace recommendations (2-5 ppm)
Engineering Controls: Local exhaust ventilation, general dilution ventilation if needed
Personal Protective Equipment: Protective gloves (nitrile or butyl), safety goggles, lab coats or chemical-resistant clothing, respiratory protection if airborne levels exceed threshold
Hygienic Practices: Wash hands before breaks and after handling, launder clothing and PPE regularly
Appearance: Clear to yellowish liquid or crystalline solid
Odor: Characteristic phenolic odor
Melting Point: 16-22°C (varies by isomer)
Boiling Point: 215-243°C
Flash Point: 84-100°C (closed cup)
Autoignition Temperature: 450-525°C
Vapor Pressure: 0.11-0.18 mmHg at 20°C
Solubility: Slightly soluble in water; soluble in ethanol, ether, benzene
Density: 0.99–1.04 g/cm³
pH: Not applicable (neutral compound)
Partition Coefficient (log Kow): 2.8–3.4
Chemical Stability: Stable under normal conditions
Reactivity: May react with strong oxidizers, forming explosive mixtures
Hazardous Reactions: May release toxic gases in contact with acids or bases
Decomposition Products: Carbon dioxide, carbon monoxide, phenolic compounds
Conditions to Avoid: Excessive heat, open flame, static discharge, incompatible chemicals
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral rat LD50 ~2360 mg/kg; can irritate airways and mucous membranes, cause nausea, headaches in moderate exposure
Chronic Exposure: Long-term contact may damage liver and kidneys; can cause dermatitis with repeated skin contact
Irritation: Eyes and skin irritation likely
Carcinogenicity: Not classified by IARC, NTP, or OSHA; no strong evidence, but related cresols show some risk in high exposures
Sensitization: Skin sensitizer in susceptible individuals
Aquatic Toxicity: Harmful to aquatic organisms; LC50 (fish, 96 h) 14-25 mg/L
Biodegradability: Readily biodegradable in soil and water, but high concentrations may persist locally
Bioaccumulation: Moderate potential in aquatic environments (log Kow >2.8)
Environmental Fate: Risk of soil and water contamination from spills; avoid uncontrolled release
Other Adverse Effects: Disrupts microbial communities at high concentrations
Waste Disposal: Collect and dispose by incineration or chemical treatment in approved facilities
Contaminated Packaging: Dispose as chemical waste; containers should be thoroughly rinsed and destroyed
Disposal Regulations: Observe national and local regulations concerning hazardous chemical waste; do not pour into drains, sewers, or natural waterways
UN Number: 2810 (Toxic liquid, organic, n.o.s.)
Proper Shipping Name: Isopropyl Cresols, solution
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Label Required: Toxic, Flammable Liquid
Marine Pollutant: Yes
Special Precautions: Secure containers, keep away from food and feedstuffs, avoid shipment with oxidizers and acids
TSCA Status: Listed
EINECS: Listed (202-001-8 for o-isopropyl cresol)
OSHA Hazards: Flammable, irritant
SARA 313: Not subject to reporting
REACH Status: Subject to restrictions in the EU
Chemical Inventory: Registered in national and international regulatory lists
Labeling Requirements: GHS-compliant labeling, hazard and precautionary statements, warning pictogram
