Product Name: Hydroquinone Dipropionate
Other Names: 1,4-Benzenediol dipropionate, Hydroquinone Propionate Ester
Recommended Use: Chemical intermediate, cosmetic additive, laboratory reagent
Manufacturer: Chemical supply or cosmetic specialty company
Address: Included as per distributor’s requirements
Emergency Phone: Provided by distributor or national emergency number
CAS Number: 7418-97-3
UN Number: Not classified under current dangerous goods regulations
Molecular Formula: C12H14O4
GHS Classification: Eye irritation (Category 2A); Skin irritation (Category 2); Specific Target Organ Toxicity – Single Exposure (Category 3)
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation. May cause respiratory irritation. Harmful if swallowed or inhaled.
Precautionary Statements: Avoid breathing dust and fumes. Wear protective gloves and goggles. Wash thoroughly after handling. Use only outdoors or in a well-ventilated area. Do not eat, drink or smoke during use.
PBT/vPvB: Not classified as PBT/vPvB as per available data
Potential Health Effects: Eyes: severe irritation, redness, pain; Skin: redness, rash; Inhalation: coughing, sore throat, possible headache; Ingestion: stomach upset, vomiting
Chemical: Hydroquinone Dipropionate
CAS Number: 7418-97-3
Concentration: >95% (pure or technical grade)
Impurities: Trace hydroquinone, propionic acid, propionyl chloride (from synthesis)
Relevant Identified Uses: In research, controlled conditions, and formulation in cosmetic products with regulated concentrations
General Advice: Move the affected person to fresh air. Call for medical attention if symptoms persist.
Inhalation: Move to fresh air, keep at rest, seek medical help if irritation or symptoms develop.
Skin Contact: Remove contaminated clothing, wash skin with soap and water for at least 15 minutes. Seek medical attention if irritation continues.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses. Continue rinsing. Obtain medical assistance.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek medical advice immediately.
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, alcohol-resistant foam, water spray for large fires
Specific Hazards: May emit irritating and toxic fumes of carbon monoxide, carbon dioxide, and possibly phenolic compounds during combustion
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear
Special Procedures: Cool exposed containers with water spray; avoid direct runoff into sewers. Combustion may produce hazardous vapors.
Personal Precautions: Wear chemical-resistant gloves, protective clothing, and tight-fitting goggles. Provide adequate ventilation and confine area.
Environmental Precautions: Prevent spillage from entering waterways, soil, and drains. Notify authorities if large releases occur.
Methods for Cleanup: Use non-sparking tools to collect powders. Absorb spill with inert material (sand, vermiculite). Place in appropriate disposal container. Wash area with water after removal. Decontaminate surfaces as required.
Prevention of Secondary Hazards: Avoid re-suspending dust; use HEPA vacuum or wet clean-up methods.
Handling: Wear proper personal protective equipment and keep away from sources of ignition. Avoid contact with skin, eyes, and clothing. Use inside fume hood or ventilated area. Wash thoroughly after handling.
Storage: Store in tightly sealed containers in a cool, dry, and well-ventilated place. Keep away from direct sunlight and incompatible substances like strong oxidizers. Do not store near food or beverages.
Special Storage Requirements: Segregate from acids and bases. Store on secondary containment trays to prevent accidental leaks. Keep container labeled.
Specific End Uses: Must follow sector-specific guidelines for safe use in industrial and laboratory settings.
Control Parameters: No occupational exposure limits established; minimize exposure using good laboratory practices
Engineering Controls: Use fume hoods or local exhaust systems. Maintain negative pressure in storage and use areas.
Personal Protective Equipment: Chemical resistant gloves (nitrile, neoprene), lab coat or chemical apron, safety goggles or face shield. Use approved respirator for high concentration scenarios.
Hygiene Measures: Wash hands before eating, drinking, or smoking. Decontaminate equipment and dispose of contaminated materials promptly. Keep work area tidy to prevent accumulation of hazardous dust.
Appearance: White to off-white crystalline powder
Odor: Faint, characteristic; can be slightly sweet
Odor Threshold: Not available
pH: Not applicable in solid state
Melting Point/Range: 40–44 °C
Boiling Point/Range: Decomposes before boiling
Flash Point: > 100 °C (estimated)
Evaporation Rate: Not applicable
Flammability: Not easily ignitable but combustible
Vapor Pressure: Negligible at room temperature
Vapor Density: Not available
Relative Density: 1.12–1.16 g/cm3
Solubility: Slightly soluble in water, readily in alcohol and organic solvents
Partition Coefficient (log Kow): Approx. 2.3
Autoignition Temperature: Not determined
Decomposition Temperature: >150 °C
Viscosity: Not applicable
Chemical Stability: Stable under recommended handling and storage conditions.
Reactivity: Low for most laboratory procedures, potential for slow hydrolysis in strong acid or base.
Hazardous Reactions: Incompatible with strong oxidizers, strong acids, bases, and reducing agents.
Decomposition Products: Propionic acid, hydroquinone, carbon monoxide, carbon dioxide under fire or high-heat scenarios.
Polymerization: No known hazardous polymerization under normal use.
Acute Toxicity: Data limited; extrapolated from hydroquinone–oral LD50 (rat) 320 mg/kg
Skin Corrosion/Irritation: Causes irritation and potential allergic reactions
Serious Eye Damage/Irritation: May cause significant irritation and watering
Respiratory or Skin Sensitization: Possible allergen on repeated or prolonged exposure
Germ Cell Mutagenicity: Based on hydroquinone, possible concern at high exposure
Carcinogenicity: Hydroquinone classified as Class 3 (not classifiable), ester form lacks conclusive data
Reproductive Toxicity: No data available for this ester
STOT (Single): May cause drowsiness or dizziness, especially in poorly-ventilated areas
STOT (Repeated): No repeated dose data for this ester; experience with hydroquinone points to kidney and liver concerns at high doses
Aspiration Hazard: None anticipated as solid
Ecotoxicity: Harmful to aquatic life in uncontrolled release; hydroquinone derivatives known to impact aquatic organisms at moderate concentrations
Persistence and Degradability: Slowly biodegradable; will hydrolyze in water to hydroquinone and propionic acid over time
Bioaccumulative Potential: Moderate (log Kow >2), but hydrolysis reduces this over time
Mobility in Soil: Limited mobility; binds to organic matter in the environment
Other Adverse Effects: Monitoring and impact assessments advised if product is used in volumes near aquatic environments
Waste Treatment Methods: Treat as hazardous organic waste. Collect in sealed, clearly labeled chemical waste containers.
Disposal of Product: Hand over to licensed disposal contractor; observed incineration under controlled temperature preferred.
Disposal of Packaging: Triple rinse and puncture prior to landfill or recycling, following local regulations.
Special Precautions: Do not discharge unused or contaminated material into natural watercourses, sewers or ambient land.
UN Number: Not regulated as dangerous goods for transport
UN Proper Shipping Name: Not classified as hazardous substance in most regions
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Environmental Hazards: Not classified as marine pollutant
Special Precautions for Transport: Avoid physical damage and exposure to sunlight, heat, or moisture during transit. Ensure containers are firmly secured and labeled. Follow national and international transport standards.
Signal Word and GHS Classification: Subject to chemical control under safety and workplace regulations in most jurisdictions
Labelling Requirements: GHS-compliant labeling with hazard and precautionary statements mandatory for quantities above research limits
REACH Compliance (EU): May require registration depending on use and tonnage
OSHA/HCS Status (US): Covered by Hazard Communication Standard
TSCA Status (US): Listed where regulated
SARA Title III: Not listed as extremely hazardous. Reporting thresholds may exist.
DSL/NDSL (Canada): Review national inventory listings
Consumer Product Restrictions: Use in cosmetics may be restricted or banned in some regions owing to hydroquinone toxicity concerns
Other Regulations: Local and state regulations may impose stricter controls; always verify current guidelines
