Boxa Chemical Group Ltd
Knowledge

Material Safety Data Sheet (MSDS): Hydroquinone Dimethyl Ether

Identification

Chemical Name: Hydroquinone Dimethyl Ether
Synonyms: 1,4-Dimethoxybenzene, p-Dimethoxybenzene, p-Methoxyphenol Dimethyl Ether
CAS Number: 150-78-7
Product Use: Intermediate in organic synthesis, fragrance, dye manufacturing
Manufacturer: [Company Name and Address]
Emergency Contact: [Phone Number]

Hazard Identification

GHS Classification: Flammable solid (Category 4), Acute toxicity (Oral, Category 5), Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation, harmful if swallowed, flammable solid
Pictograms: Exclamation mark, Flame
Precautionary Statements: Keep away from open flames, avoid breathing dust, use personal protection for skin and eyes

Composition / Information on Ingredients

Chemical Formula: C8H10O2
Component: Hydroquinone Dimethyl Ether
Concentration: >99%
Impurities: Trace phenolic derivatives, residual solvents, moisture less than 0.5%

First Aid Measures

Inhalation: Move exposed person to fresh air immediately, loosen clothing at neck and waist, seek medical attention if symptoms appear
Skin Contact: Wash skin thoroughly with plenty of water and mild soap for at least 15 minutes, remove contaminated clothing, medical care required if irritation persists
Eye Contact: Rinse eyes cautiously with water for several minutes, remove contact lenses if possible, continue rinsing, seek medical help if irritation remains
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical assistance

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam, water spray (avoid direct water stream as it may spread material)
Specific Hazards: Produces toxic fumes of carbon monoxide, carbon dioxide, possible phthalic anhydride
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus (SCBA) and full protective clothing
Firefighting Instructions: Approach fire from upwind, contain runoff, avoid inhaling vapors and residues

Accidental Release Measures

Personal Precautions: Wear gloves, face shield, goggles, and suitable protective clothing, ventilate area well
Environmental Precautions: Prevent substance from entering drains, watercourses, or soil
Methods for Cleaning Up: Shovel or sweep up, place in suitable labeled sealed containers, wash spill site thoroughly after material pickup

Handling and Storage

Handling Precautions: Maintain good industrial hygiene, avoid contact with skin and eyes, use only with adequate ventilation, keep away from ignition sources
Storage Conditions: Store in cool, dry, well-ventilated area away from oxidizers, acids, and direct sunlight, keep container tightly sealed
Incompatibilities: Strong oxidizing agents, acids, bases
Hygiene Measures: Wash thoroughly after handling, maintain clean work clothing, never eat or drink near material

Exposure Controls and Personal Protection

Exposure Limits: No specific OSHA or ACGIH exposure limits set, control is based on minimizing dust
Engineering Controls: Use local exhaust ventilation, process enclosure, face shield or chemical splash goggles
Personal Protection: Butyl rubber or nitrile gloves, chemical-resistant apron, safety goggles or face shield, NIOSH approved respirator under dust forming conditions
Skin and Body Protection: Laboratory coat, protective boots
Hygiene Practices: No contact with skin, eyes, clothes; wash hands after handling

Physical and Chemical Properties

Appearance: White crystalline solid
Odor: Characteristic, sweet aromatic
Melting Point: 54–57 °C
Boiling Point: 174–175 °C (at 760 mmHg)
Flash Point: 73 °C
Vapor Pressure: 0.08 mmHg at 25 °C
Solubility: Slightly soluble in water, readily soluble in ethanol and ether
Specific Gravity: 1.07 (water = 1)
Partition Coefficient (octanol/water): 1.85
pH: Not applicable
Evaporation Rate: No data available

Stability and Reactivity

Chemical Stability: Stable under normal conditions, sensitive to strong oxidizers and acids
Reactivity: May react vigorously with strong oxidizing agents
Decomposition: Produces toxic gases, including carbon monoxide and carbon dioxide, on combustion or thermal decomposition
Conditions to Avoid: Heat, moisture, flames, sparks
Incompatible Materials: Oxidizing materials, concentrated nitric and sulfuric acids
Hazardous Polymerization: Will not occur

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 1500–3000 mg/kg
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms of Exposure: Irritation of eyes, skin, respiratory tract, possible headache, dizziness, weakness
Chronic Effects: Prolonged exposure may cause dermatitis, possible liver or kidney effects based on animal studies
Carcinogenic Status: Not classified as carcinogen by IARC, NTP, ACGIH, or OSHA
Mutagenicity and Reproductive Toxicity: No strong evidence from animal or epidemiological studies

Ecological Information

Aquatic Toxicity: Harmful to aquatic life, toxic to fish and invertebrates under high concentration
Persistence and Degradability: Readily biodegradable in environment, tends to break down to smaller organic compounds
Bioaccumulation: Low potential, partition coefficient suggests minimal logP values
Mobility in Soil: Moderate, more soluble in organic solvents than in water
Other Adverse Effects: No known ozone depletion potential, not expected to bioconcentrate in food chains

Disposal Considerations

Waste Treatment Methods: Small quantities may be dissolved in combustible solvent and incinerated in a chemical incinerator with afterburner and scrubber
Container Disposal: Containers should be triple rinsed and then punctured or otherwise rendered unusable before disposal in accordance with local environmental regulations
Environmental Precautions: Do not allow product or residue to enter water systems, soil, or drains
Disposal Regulations: Dispose of in accordance with federal, state, and local requirements

Transport Information

UN Number: Not classified as dangerous for transport under UN, IMO, or IATA
Transport Hazard Class: Not regulated
Packing Group: None
Proper Shipping Name: Hydroquinone Dimethyl Ether
Special Precautions for Transport: Keep container tightly closed and upright during transport, avoid breakage or exposure to heat sources

Regulatory Information

TSCA Status: Listed in the United States TSCA Inventory
OSHA: Not specifically regulated as a hazardous material
SARA Title III: Not listed for specific reporting under Sections 302, 304, 313
California Proposition 65: Not listed as a known carcinogen or reproductive toxin
European Regulations: Listed in EINECS/ELINCS; classified as Xi (Irritant) under EU directives
Label Requirements: Warning labels required for workplace safety, including hazard pictograms and statements in accordance with GHS