Product Name: Hydroquinone-Beta-D-Glucopyranoside
Chemical Formula: C12H16O7
Synonyms: Arbutin
CAS Number: 497-76-7
Intended Use: Laboratory chemicals, manufacturing of cosmetic and pharmaceutical products
Manufacturer Information: Contact information typically provided on packaging or safety data bulletin
Emergency Phone Number: Refer to local regulatory agency or poison control center
Recommended Restrictions: Professional use only; not intended for direct ingestion or application to large skin areas unformulated
Hazard Classification: Eye irritation Category 2A, Skin sensitization Category 1, Specific target organ toxicity – single exposure Category 3
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; may cause skin sensitization; may cause respiratory irritation
Pictograms: Exclamation mark symbol indicated by GHS
Precautionary Statements: Avoid inhalation of dust; wash thoroughly after handling; use only in well-ventilated areas
Unusual Hazards: Dust may form explosive mixtures with air; long-term exposure may increase risk of allergy or skin sensitization
Symptoms of Exposure: Redness, irritation of eyes and skin, coughing, sneezing, respiratory discomfort
Other Hazards: Not classified as carcinogenic by IARC or NTP
Chemical Name: Hydroquinone-Beta-D-Glucopyranoside
Common Name: Arbutin
Concentration: 98-100% purity
Impurities: Trace hydroquinone (typically less than 0.1%)
Molecular Weight: 272.26 g/mol
EC Number: 207-850-3
Other Components: No additional hazardous components reported
Eye Contact: Rinse well with plenty of water for at least 15 minutes, lifting upper and lower eyelids, seek medical attention for continued irritation
Skin Contact: Remove contaminated clothing, wash skin with soap and water, consult a doctor if symptoms develop
Inhalation: Move to fresh air, keep at rest in a comfortable position, consult physician if respiratory symptoms persist
Ingestion: Rinse mouth with water, do not induce vomiting unless advised by medical personnel, seek immediate medical care
Most Important Symptoms: Itching, burning, redness, possible allergic reactions on repeated exposures
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Specific Hazards: Combustion can release carbon monoxide, carbon dioxide, and potentially irritating or toxic fumes
Protective Equipment and Precautions: Firefighters must wear self-contained breathing apparatus and full protective gear
Fire Fighting Instructions: Use water spray to cool containers, avoid inhaling combustion vapors, prevent runoff from entering water supplies
Flash Point: Not highly flammable under normal circumstances but fine dust may pose hazard
Explosion Data: Dust accumulation can pose risk of explosion if exposed to ignition sources
Personal Precautions: Evacuate unnecessary personnel, avoid breathing dust, wear suitable protective clothing and gloves, ensure adequate ventilation
Environmental Precautions: Prevent material from contaminating drains or entering natural water sources
Containment: Scoop up material and place in a suitable, labeled waste container; dampen any dust with water mist to minimize airborne particles
Cleanup Methods: Clean spill area thoroughly, ventilate area, wash surfaces with water after cleanup
Safe Handling Advice: Avoid contact with skin, eyes, and clothing, avoid inhaling dusts or aerosols; wash hands after use; use only in well-ventilated spaces
Storage Conditions: Store in tightly sealed original container, away from sources of ignition and strong oxidizers, at temperatures between 2°C and 8°C
Incompatible Materials: Strong acids, strong bases, oxidizing agents
Other Precautions: Keep out of reach of children, store in a cool, dry location away from direct sunlight
Occupational Exposure Limits: No established limits for arbutin; observe general chemical exposure guidelines
Engineering Controls: Local exhaust ventilation or process enclosure for dust control
Personal Protective Equipment: Safety glasses or goggles, protective gloves made of nitrile or neoprene, lab coat, particulate respirator when risk of inhalation
Hygiene Measures: Remove contaminated clothing, wash hands before eating, drinking, or smoking
Appearance: White to off-white crystalline powder
Odor: Odorless
pH: Approximately 6.0 (1% aqueous solution)
Melting Point: 193°C
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Non-flammable as a solid
Solubility: Readily soluble in water, sparingly soluble in ethanol
Vapor Pressure: Negligible at ambient temperature
Density: Approximately 1.54 g/cm³
Partition Coefficient (log Kow): -1.5 (estimated)
Decomposition Temperature: Above 200°C
Chemical Stability: Stable under recommended use and storage conditions
Incompatible Materials: Strong acids, oxidizing agents, alkalis
Decomposition Products: Carbon monoxide, carbon dioxide, hydroquinone
Reactivity: Not expected to be highly reactive, but avoid exposure to light or heat over long periods
Hazardous Polymerization: Will not occur under normal conditions
Acute Toxicity: LD50 (oral, rat): approx. 9800 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Potential Effects: Eye and skin irritation, possible sensitization with repeated exposure, respiratory irritation
Carcinogenicity: Not identified as a carcinogen by IARC, ACGIH, NTP, or OSHA
Mutagenicity and Reproductive Toxicity: Animal studies show low risk at typical exposure levels
Chronic Effects: Potential risk of allergic reaction after repeated exposure; no established evidence of chronic systemic toxicity
Aquatic Toxicity: Low toxicity to aquatic organisms, LC50 (fish, 96hr): >100 mg/L
Persistence and Degradability: Biodegradable, degrades through microbial action in soil and water
Bioaccumulation: Not likely to bioaccumulate (log Kow below zero)
Mobility in Soil: High water solubility suggests high mobility in soil and water environments
Other Effects: No significant adverse ecological impact reported under normal use
Waste Disposal Methods: Dispose of as non-hazardous chemical waste in accordance with local, regional, national, and international regulations
Contaminated Packaging: Rinse and recycle or dispose of containers following official guidelines
Special Precautions: Do not allow material to reach sewage system or surface water
Recommended Disposal Site: Approved landfill site or incineration facility
UN Number: Not classified as a dangerous good for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Environmental Hazards: No
Special Precautions for User: Prevent dust release during transport; keep in original sealing; avoid contact with food and feed
Transport in Bulk: Not recommended, product provided in small, sealed containers
OSHA Status: Not regulated as a hazardous substance
TSCA Status: Listed
EINECS/ELINCS: Listed in European inventory
DSL/NDSL Canada: Listed
SARA 313: Not subject
California Proposition 65: Not listed as a chemical known to cause cancer or reproductive harm
WHMIS Canada: Not classified as hazardous
REACH Compliance: Exempt as naturally occurring substance
