Cresol Purple - Material Safety Data Sheet (MSDS)
Identification
- Product Name: Cresol Purple
- Chemical Name: o-Cresolsulfonphthalein
- Synonyms: Cresol Red, Cresolsulfonephthalein
- CAS Number: 62625-29-0
- Recommended Uses: Laboratory reagent, pH indicator
- Supplier: Details available on the supplier label or safety documentation
- Emergency Contact: Company-specific emergency numbers and local poison control centers should be referenced during incidents
Hazard Identification
- Classification: Not labeled as a hazardous substance under GHS; certain reactions can create irritant conditions
- Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
- Hazard Statements: May cause irritation to skin, eyes, and respiratory tract; contact with large quantities or prolonged exposure increases risk
- Precautionary Statements: Avoid breathing dust; use protective equipment; wash exposed skin thoroughly after handling material
- Signal Word: Not classified under GHS with specific danger or warning for small laboratory use, but exercise caution
- Symptoms: Redness, discomfort, coughing, gastrointestinal upset in severe cases
- Other Hazards: No evidence of carcinogenicity according to available data; chronic exposure data is limited
Composition / Information on Ingredients
- Cresol Purple Content: >98% pure, may contain trace impurities
- Chemical Formula: C21H18O5S
- Molecular Weight: 382.43 g/mol
- Ingredient Disclosure: No known toxic impurities present above disclosure limits
First Aid Measures
- Inhalation: Move to fresh air promptly; seek medical advice if breathing difficulties persist
- Skin Contact: Remove contaminated clothing; rinse affected area with soap and water for several minutes
- Eye Contact: Rinse eyes cautiously with water for several minutes; remove contact lenses if possible; continue rinsing
- Ingestion: Rinse mouth; seek medical attention if feeling unwell; do not induce vomiting unless directed by medical personnel
- Most Important Symptoms: Mild to moderate irritation or redness; persistent symptoms require doctor evaluation
- Medical Attention: Show safety data sheet or label to health professionals
Fire-Fighting Measures
- Suitable Extinguishing Media: Water mist, CO₂, dry chemical, foam
- Unsuitable Media: Avoid direct streams of water, which could spread powder
- Specific Hazards: Burning may produce irritating fumes, including carbon oxides and sulfur oxides
- Protective Equipment: Wear self-contained breathing apparatus and full protective gear in confined fires
- Special Procedures: Control runoff to prevent contamination of waterways; ventilate area after extinguishing flames
Accidental Release Measures
- Personal Precautions: Use proper personal protection including gloves, lab coat, eye protection, and dust mask if needed
- Environmental Precautions: Avoid discharge into drains, water courses, or soil
- Clean-up Methods: Sweep up material carefully; place in sealable, labeled waste container; ventilate area thoroughly after cleanup
- Decontamination: Wash spill area with water and mild detergent; prevent dust formation during cleanup
Handling and Storage
- Handling: Avoid contact with skin, eyes, and clothing; minimize dust generation and accumulation; use in a well-ventilated environment
- Hygiene Practices: Wash hands and exposed skin before eating, drinking, or smoking after handling...contaminated clothing should not be reused until properly cleaned
- Storage Conditions: Store in tightly closed containers; keep in a cool, dry, ventilated area; avoid direct sunlight and sources of ignition or excessive heat
- Incompatible Materials: Keep away from strong oxidizers and acids
- Storage Class: General chemical storage according to institutional guidelines
Exposure Controls and Personal Protection
- Engineering Controls: Use fume hood or adequate ventilation to keep airborne concentrations low
- Respiratory Protection: Wear approved dust mask or respirator if powder or dust is generated during use
- Skin Protection: Nitrile gloves recommended due to the chemical’s potential to cause irritation; inspect gloves before use and discard damaged ones
- Eye Protection: Chemical safety goggles with side shields minimize risk of contact
- Body Protection: Laboratory coat or apron prevents contact with street clothing or exposed skin
- Environmental Control: Keep workplace clean; prevent material releases to the environment
Physical and Chemical Properties
- Appearance: Purple to reddish powder or crystals
- Odor: Odorless or faint organic scent
- pH: 3.4 – 8.8 (indicator range in solution)
- Melting Point: 220 °C (428 °F) with decomposition
- Boiling Point: Not applicable (decomposes)
- Flash Point: Not flammable under normal conditions
- Solubility: Slightly soluble in water, freely soluble in alcohol and other organic solvents
- Vapor Pressure: Not available or negligible at ambient temperature
- Density: Approximately 1.4 g/cm³
- Partition Coefficient: Not determined
- Other Properties: Forms fine dust when handled as a powder; stable in dry, sealed packaging
Stability and Reactivity
- Chemical Stability: Stable under normal temperatures and recommended storage conditions
- Reactivity: Shows low reactivity under ambient laboratory conditions
- Conditions to Avoid: Excessive humidity, direct sunlight, strong oxidizers or acids
- Hazardous Decomposition: May release carbon oxides and sulfur oxides on decomposition above melting temperature
- Polymerization: Not expected to occur
Toxicological Information
- Acute Effects: Dust can cause irritation to eyes, skin, and upper respiratory tract; ingestion in significant amounts could upset stomach
- Chronic Effects: No evidence for mutagenicity, carcinogenicity, or reproductive toxicity based on current research
- Sensitization: No known sensitization reactions reported in standard laboratory use
- LD50 Values: Not established for this compound according to publicly available sources, but not known to be acutely toxic
- Medical Conditions Aggravated by Exposure: Pre-existing allergies or skin sensitivities may increase response severity
Ecological Information
- Toxicity to Aquatic Life: Expected to be low but not fully tested; do not allow to enter drains or natural waters
- Persistence and Degradability: Degrades slowly in the environment through chemical or biological processes
- Bioaccumulative Potential: No significant bioaccumulation is anticipated due to limited solubility and rapid degradation
- Mobility: Low mobility in soil and water; binds to particles and organic matter
- Other Adverse Effects: No known significant effects or hazards under recommended disposal and use
Disposal Considerations
- Waste Disposal: Dispose as hazardous laboratory chemical waste according to local, regional, and national regulations; incineration in authorized facilities preferred
- Contaminated Packaging: Empty packaging should be treated and disposed of in the same way as unused chemical
- Waste Codes: Follow guidelines provided by authorities for laboratory waste or unlisted hazardous chemicals
- Precautions for Disposal: Avoid release to environment; do not mix with incompatible wastes
Transport Information
- UN Number: Not regulated for transport under major international guidelines for laboratory quantities
- Transport Hazard Class: Not assigned under standard court systems
- Packing Group: Not classified for transport packing group
- Proper Shipping Name: Cresol Purple (not restricted in small laboratory container sizes)
- Special Precautions: Package securely to prevent spills; transport in compliance with institutional and regional chemical transport policies
- Environmental Hazards: Not expected under normal handling and shipping for laboratory supply
Regulatory Information
- TSCA Inventory: Listed in the United States Toxic Substances Control Act Inventory
- OSHA: Not regulated as a hazardous material under the OSHA Hazard Communication Standard
- REACH Registration: Subject to European Union REACH obligations for chemical supply; check with suppliers regarding registration status for larger scale use
- SARA Title III: Not listed under Section 302, 304, or 313 Toxic Release Inventory
- California Prop 65: Not listed as a chemical known to cause cancer or reproductive harm
- Other: Consult national, regional, and local regulations governing laboratory or industrial chemical use and waste