Boxa Chemical Group Ltd
Knowledge

Material Safety Data Sheet for Bioactive Quinone

Identification

Product Name: Bioactive Quinone
Chemical Name: Quinone, 1,4-Benzoquinone derivative
Formula: C6H4O2
Synonyms: p-Benzoquinone, Bio-Quinone
Recommended Use: Laboratory reagent, biochemical research, pharmaceutical applications
Supplier Information: Manufacturer address, emergency contact numbers, email for technical support
CAS Number: 106-51-4
UN Number: 2587

Hazard Identification

Classification: Acute toxicity (oral and dermal), Eye irritation, Skin sensitization
Hazard Statement: May cause irritation to eyes, skin, and respiratory tract; Harmful if swallowed or absorbed through the skin; Suspected of causing genetic defects
Signal Word: Danger
Precautionary Statement: Avoid contact with skin, eyes, and clothing; Use personal protective equipment; Always work in a well-ventilated area; Do not breathe dust or vapors
GHS Pictograms: Skull and crossbones, exclamation mark, health hazard
Symptoms of Exposure: Redness, rash, headache, nausea, coughing, difficulty breathing
Potential Health Effects: Acute exposure may result in severe irritation or systemic toxicity; Chronic exposure may pose risks of mutagenicity or carcinogenicity

Composition / Information on Ingredients

Chemical Identity: 1,4-Benzoquinone
Concentration: 99% purity
Other Components: Trace impurities (less than 1%), may include oxidation byproducts
Molecular Weight: 108.09 g/mol

First Aid Measures

Inhalation: Move to fresh air as quickly as possible; Keep person calm; Seek immediate medical attention for symptoms like dizziness, persistent cough, or respiratory distress
Skin Contact: Remove contaminated clothing right away; Wash skin thoroughly with mild soap and plenty of water for at least 20 minutes; Seek medical help if any irritation develops or persists
Eye Contact: Rinse eyes cautiously with water for several minutes, lifting eyelids occasionally; Remove contact lenses if present and easy to do; Continue rinsing; Consult an eye specialist immediately
Ingestion: Rinse mouth well; Do not induce vomiting; Seek medical advice immediately; Never give anything by mouth to a person who is unconscious
Most Important Symptoms: Burning, redness, blistering, respiratory discomfort, headache, or nausea
Indication for Medical Attention: Immediate medical care is needed for significant exposure, especially if symptoms do not resolve

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, foam, dry chemical, or carbon dioxide
Unsuitable Media: Avoid using high-pressure water streams that may spread the material
Hazards from Burning: Toxic fumes release on combustion, such as carbon monoxide, carbon dioxide, and phenolic vapors
Protective Equipment for Firefighters: Full protective gear including breathing apparatus; Isolate area; Fight fire from safe distance
Advice for Firefighters: Prevent runoff into drains; Cool containers with water spray to reduce pressure increase

Accidental Release Measures

Personal Precautions: Wear chemical-resistant gloves, safety goggles, and appropriate respirator if ventilation is inadequate; Evacuate unprotected persons from area
Environmental Precautions: Prevent spillage from reaching drains or waterways; Alert authorities if contamination is extensive
Cleanup Procedures: Ventilate affected area; Absorb small spills using inert absorbents like sand or vermiculite; Place in labeled containers for disposal as hazardous waste; Decontaminate area after cleanup
Emergency Procedures: Notify safety personnel immediately in case of a major release or exposure; Secure area to prevent access

Handling and Storage

Safe Handling: Use only in well-ventilated fume hoods or enclosed systems; Minimize direct contact; Keep containers closed outside of use
Hygiene Practices: Always wash hands thoroughly after handling; Remove contaminated clothing; Avoid eating, drinking, or smoking during use
Conditions for Safe Storage: Store in cool, dry, well-ventilated area away from direct sunlight and incompatible substances like strong acids, oxidizers, and bases; Use tightly sealed, clearly labeled containers
Special Requirements: Secondary containment preferred; Access restricted to trained personnel

Exposure Controls and Personal Protection

Occupational Exposure Limits: ACGIH TLV 0.1 ppm (TWA), OSHA PEL not established for quinone specifically
Engineering Controls: Use laboratory exhaust hoods, local exhaust ventilation, or other mechanical means to keep air concentrations low
Personal Protective Equipment: Butyl or nitrile gloves, chemical splash goggles, face shield for large-scale handling, disposable coveralls or protective lab coat, closed footwear
Respiratory Protection: NIOSH/MSHA-approved respirator required for airborne concentrations or accidental release
Environmental Controls: Use in designated chemical fume areas with spill control procedures in place

Physical and Chemical Properties

Appearance: Bright yellow, crystalline solid or powder
Odor: Strong, sharp, chlorine-like odor
Odor Threshold: Detectable at low concentrations
Melting Point: 115-116°C (239-241°F)
Boiling Point: 155-156°C at 760 mmHg
Solubility: Slightly soluble in water, readily soluble in ethanol, ether, and acetone
Vapor Pressure: 1.2 mmHg at 25°C
pH: Not applicable in solid state
Flash Point: 79°C (175°F)
Evaporation Rate: Not available
Flammability: Combustible solid
Partition Coefficient (log Kow): 0.22
Decomposition Temperature: Above 180°C

Stability and Reactivity

Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong reducing agents, strong acids, and some metals
Hazardous Reactions: May polymerize or decompose in presence of alkalis, high temperature, or light
Decomposition Products: Produces toxic gases like carbon monoxide and phenolic vapors on combustion or decomposition
Conditions to Avoid: Avoid heat, flame, sparks, moisture, and uncontrolled mixing with incompatible substances or solvents

Toxicological Information

Acute Toxicity: LD50 (oral, rat): 130 mg/kg; LD50 (dermal, rabbit): 366 mg/kg
Inhalation Effects: May cause lung irritation, coughing, and difficulty breathing if inhaled
Skin Effects: Can cause redness, blistering, allergic reaction, or chemical burns
Eye Effects: Causes severe irritation, redness, watering, and possible corneal injury
Chronic Effects: Repeated exposure may trigger sensitivity or dermatitis; Suspected risk of mutagenicity and carcinogenicity;
Sensitization: May cause allergic skin reaction on prolonged or repeat contact
Target Organs: Lungs, skin, liver, kidneys

Ecological Information

Ecotoxicity: Toxic to aquatic organisms at low concentrations; Not rapidly degradable in the environment
Persistence and Degradability: Moderate persistence; Partial breakdown in soil and water due to microbial action
Bioaccumulative Potential: Low to moderate; Limited potential to build up in fish tissue
Mobility in Soil: Moderate mobility; Can leach in areas of high rainfall or poor containment
Other Adverse Effects: Contributes to chemical oxygen demand and aquatic toxicity; Precautions recommended to avoid environmental release

Disposal Considerations

Waste Disposal Methods: Treat as hazardous chemical waste; Contaminated material should be incinerated at a licensed facility; Consult local, regional, and national authority for disposal rules
Container Disposal: Empty containers must be decontaminated and disposed of according to applicable environmental regulations
Precautions: Do not flush to sewer or allow product to reach soil or watercourses; Keep waste in tightly closed, clearly labeled containers

Transport Information

UN Number: 2587
UN Proper Shipping Name: Benzoquinone, solid
Transport Hazard Class: 6.1 (Toxic substance)
Packing Group: II
Labels Required: Toxic (Skull and Crossbones), environmentally hazardous substance
Special Precautions: Keep containers upright and tightly sealed during transport; Do not transport with incompatible chemicals or foodstuffs; Emergency contact details must accompany shipment
Environmental Hazards: Marine pollutant label often required for bulk shipment

Regulatory Information

OSHA Status: Hazardous chemical, with enforced handling and exposure standards
TSCA Inventory: Listed
SARA Title III: Not subject to Section 313 reporting
RCRA Status: Classified hazardous waste, U206
REACH Status: Registered under applicable European regulations
WHMIS Classification: Class D2A (very toxic), Class D2B (irritant)
Other National/International Regulations: Subject to chemical safety and environmental regulations in jurisdictions such as EU, Canada, Japan, and Australia
Label Elements: Includes health and environmental warnings as required; End users must be informed about exposure risks, protective measures, and safe disposal