Boxa Chemical Group Ltd
Knowledge

Material Safety Data Sheet for 6-Amino-m-Cresol

Identification

Product Name: 6-Amino-m-Cresol
Chemical Formula: C7H9NO
CAS Number: 2835-98-5
Synonyms: 3-Cresol-6-amine, 6-Aminometacresol
Recommended Use: Intermediate for dyes, research, laboratory use
Manufacturer Contact: Supplier information required on shipment paperwork
Emergency Number: Emergency services or manufacturer’s provided line

Hazard Identification

Physical State: Solid, crystalline powder
Color: Off-white to light brown
GHS Classification: Acute toxicity (oral, dermal, inhalation), serious eye irritation, skin sensitization
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause allergic skin reaction, hazardous to aquatic environment
Signal Word: Warning
Pictograms: Exclamation mark, health hazard, aquatic toxicity
Routes of Entry: Inhalation, skin absorption, ingestion
Target Organs: Liver, kidneys, central nervous system
Health Effects: May cause headaches, respiratory irritation, allergic dermatitis, eye discomfort, nausea on significant ingestion or exposure

Composition / Information on Ingredients

Chemical Name: 6-Amino-m-Cresol
CAS Number: 2835-98-5
Concentration: ≥98% pure
Impurities: Trace related isomers or residual solvents may be present in commercial batches
Additives: No additional stabilizers or preservatives indicated for standard laboratory supply

First Aid Measures

Inhalation: Move person to fresh air, keep them calm and warm, seek immediate medical help for persistent symptoms like shortness of breath, coughing, or chest pain
Skin Contact: Remove contaminated clothing, rinse area thoroughly with soap and water, monitor for skin rash or burns, get help if irritation persists
Eye Contact: Flush open eyes gently but thoroughly with running water for at least 15 minutes, check for redness or vision changes, bring person promptly to a physician
Ingestion: Rinse mouth slowly, do not induce vomiting, offer small amounts of water if conscious, call a poison control center or healthcare provider for guidance

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, alcohol-resistant foam
Specific Hazards: Heat may produce toxic fumes such as nitrogen oxides and phenolic compounds
Personal Precautions: Wear self-contained breathing apparatus, full protective gear, avoid inhaling fumes
Combustion Products: Hazardous gases including CO, CO2, NOx, cresol derivatives
Firefighting Instructions: Keep containers cool with water spray, isolate fire area, avoid runoff into drains and water supplies

Accidental Release Measures

Personal Precautions: Use chemical splash goggles, gloves, dust mask or respirator, prevent skin and eye contact
Environmental Precautions: Do not allow runoff into sewers, surface waters, or soil, block all spill paths
Methods for Cleanup: Ventilate the area, collect spill on dry absorbent material, scoop gently into appropriate labeled waste container, wash area thoroughly with soap solution, follow up with regulatory disposal rules

Handling and Storage

Handling: Use only in well-ventilated areas, avoid raising dust, keep containers tightly sealed, do not eat, drink, or smoke near product, launder clothes after handling
Storage: Store in a cool, dry, well-ventilated space, protect from light and moisture, label containers properly, reserve storage for chemicals away from food and acid/base reagents, maintain temperature stability to prevent degradation

Exposure Controls and Personal Protection

Exposure Limits: No official TLV/PEL established specifically for 6-Amino-m-Cresol, use general limits for phenolic amines and organic dust
Engineering Controls: Exhaust ventilation, local fume hood, closed handling systems for large-scale use
Personal Protection: Approved chemical safety goggles, nitrile or butyl rubber gloves, protective lab coat, remove contaminated clothing promptly, NIOSH-approved respiratory protection for dust or vapor, do not reuse gloves

Physical and Chemical Properties

Appearance: Fine powder, off-white to pale brown shade
Odor: Mild, phenolic smell
Molecular Weight: 123.15 g/mol
Melting Point: 128–132°C
Boiling Point: Decomposition occurs before boiling
Solubility: Moderate in water, higher in ethanol and organic solvents
Vapor Pressure: Minimal at room temperature
Density: 1.13 g/cm3
pH: Typically neutral to slightly basic in solution
Other Properties: Non-volatile in standard lab settings, stable under normal pressures, light sensitive

Stability and Reactivity

Chemical Stability: Stable if kept cool, dry, protected from light
Conditions to Avoid: High humidity, excess heat, direct sunlight, exposure to strong acids and bases
Incompatible Materials: Strong oxidizers, acid chlorides, acyl halides, anhydrides
Hazardous Decomposition: May release toxic fumes such as aniline derivatives, cyanic gases, phenol vapors on decomposition

Toxicological Information

Acute Toxicity: Oral LD50 rats: ~500–800 mg/kg
Inhalation: Irritation to mucous membranes, airways, coughing, headache
Skin Contact: Can cause allergy or chemical burns, redness, swelling on prolonged exposure
Eye Contact: Irritation, possible blurred vision, conjunctivitis
Chronic Effects: Prolonged or repeat exposure can lead to liver or kidney function changes, allergic sensitization
Carcinogenicity: No data indicating carcinogenic link in humans, insufficient long-term studies
Mutagenicity: Limited available data, use with caution

Ecological Information

Ecotoxicity: Harmful to aquatic life even at low concentrations, causes long term adverse effects in the aquatic environment
Persistence: Not rapidly biodegradable, may persist in soil and sediment
Bioaccumulation: Potential for accumulation in aquatic organisms, high log Kow
Mobility in Soil: Moderate mobility, can leach through the soil and contaminate groundwater
Other Effects: Major spills raise risk for fish, plankton, and aquatic plants, rinse waters must not enter waterways

Disposal Considerations

Waste Disposal: Treat as hazardous chemical waste, package securely in appropriate drums, incinerate in controlled facility, avoid landfill release
Contaminated Containers: Empty containers must be triple rinsed, punctured, sent for hazardous waste treatment
Local Regulations: Follow national, state, and municipal environmental management standards, consult licensed waste disposal contractors, document disposal activities

Transport Information

UN Number: Not assigned for small laboratory quantities; large shipments may require special paperwork
Transport Hazard Class: Not regulated for small packages, classified as hazardous for bulk transport
Packing Group: III (if regulated as toxic solid)
Special Provisions: Protect from moisture, ship separately from foodstuffs, declare properly on manifest
Labels: Toxic, environmental hazard, handle under appropriate shipping code
Shipment Restrictions: By air: consult airline DG department; By road/rail: compliant with local rules, placard as required

Regulatory Information

TSCA: Listed in US inventory
ECHA REACH: Subject to pre-registration and notification in the EU
OSHA: Subject to workplace safety communication standards
WHMIS (Canada): Requires signal word and hazard statement
ADR/RID/IMDG: Not classified for most forms, but consult local authority for bulk shipments
Other National/International Regulations: Subject to regional chemical controls in Asia Pacific, South America, Africa based on end user’s location, consult safety officer for compliance