Product Name: 5-Amino-O-Cresol
Chemical Formula: C7H9NO
Synonyms: 5-Amino-2-methylphenol, 2-Methyl-5-aminophenol
CAS Number: 2835-99-6
Recommended Use: Dye intermediate, chemical research
Manufacturer Details: Chemical supplier and contact details provided on packaging
Emergency Contact Number: Listed on shipped container label or regional safety response number
REACH Registration Number: Available for European countries through local distributor
GHS Classification: Acute toxicity (oral), Skin sensitization, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause allergic skin reactions
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, wash skin thoroughly after handling, wear protective gloves and eye protection, do not eat, drink, or smoke during use
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Effects of Overexposure: Redness, itching, swelling, nausea, gastrointestinal distress, headache
Chemical Name: 5-Amino-2-methylphenol
Percentage by Weight: >98%
Impurities: Trace phenolic and aminophenol derivatives
Molecular Weight: 123.15 g/mol
EC Number: 220-619-0
Index Number (Annex VI): Not assigned
Inhalation: Move to fresh air, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash area thoroughly with plenty of soap and water, consult medical personnel for irritation
Eye Contact: Rinse eyes gently with water for 15–20 minutes while holding eyelids open, remove contact lenses if possible, continue rinsing, seek professional care
Ingestion: Rinse mouth, do not induce vomiting, drink water if conscious, obtain immediate medical help
Symptoms: Burning sensation, respiratory discomfort, mild gastrointestinal upset, potential allergenic response
Immediate Medical Attention: Strongly recommended in case of severe exposure or persistent effects
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray for larger fires
Unsuitable Extinguishing Media: Strong water jets may spread dust
Fire Hazards: Combustible solid, releases toxic fumes of nitrogen oxides and carbon monoxide under fire
Protection for Firefighters: Use self-contained breathing apparatus and chemical-resistant protective clothing
Firefighting Procedures: Evacuate area, prevent runoff into water sources, cool containers with water spray
Decomposition Products: Nitrogen oxides, carbon monoxide, irritant gases
Personal Precautions: Isolate area, avoid dust formation, use respiratory protection and gloves
Environmental Precautions: Prevent run-off into drains, surface water, or soil
Spill Containment: Sweep up material without creating dust, place in properly labeled container for disposal
Cleaning Methods: Clean surfaces with water and detergent, ventilate area
Decontamination: Ensure proper disposal of cleaning materials in line with local regulations
Handling: Use only in well-ventilated areas, minimize dust generation, avoid contact with eyes, skin, and clothing, do not eat, drink, or smoke during handling
Storage Conditions: Store in tightly closed, properly labeled containers, in a cool, dry location away from incompatible materials such as strong oxidizers and acids
Incompatible Materials: Strong acids, strong oxidizing agents, bases
Special Requirements: Keep containers tightly sealed, segregate from food and feedstuffs
Occupational Exposure Limits: No established national or international exposure limits
Engineering Controls: Local exhaust ventilation, process enclosures
Respiratory Protection: Approved filter mask (NIOSH or EN standards) for dust
Eye Protection: Chemical safety goggles
Hand Protection: Chemical-resistant gloves (nitrile, neoprene)
Skin Protection: Wear suitable protective clothing (long sleeves, laboratory coat)
Hygiene Measures: Wash thoroughly after handling, do not reuse contaminated clothing, maintain clean work environment
Appearance: Light brown to beige crystalline powder
Odor: Faint phenolic
Melting Point: 154–157°C
Boiling Point: Not applicable (decomposes)
pH: Slightly acidic to neutral in water solution
Solubility: Moderate in water, soluble in ethanol and acetone
Density: Approximately 1.18 g/cm³
Vapor Pressure: Not significant at room temperature
Partition Coefficient: log Pow estimated around 0.8
Flash Point: >110°C (closed cup, estimated)
Auto-Ignition Temperature: Not established
Explosive Properties: No data, not expected to form explosive dust-air mixtures under typical conditions
Chemical Stability: Stable under recommended handling and storage conditions
Decomposition: Decomposes on heating producing toxic gases (nitrogen oxides, carbon monoxide)
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Reactions: May react vigorously with oxidizing agents
Polymerization: Not expected under normal conditions
Thermal Degradation: Avoid exposure to excessive heat, sparks, flame
Acute Toxicity: Harmful if swallowed (oral LD50 in rats approx. 200–500 mg/kg, based on related aminophenols)
Skin Irritation: Causes mild to moderate irritation
Eye Irritation: Causes irritation and possible damage with prolonged exposure
Respiratory Irritation: Dust may cause nose and throat irritation
Skin Sensitization: Possibility of allergic reaction in susceptible individuals
Repeated Dose Toxicity: No specific data, but similar compounds show risk of organ effects after chronic overexposure
Carcinogenicity: Not classified as carcinogenic by NTP, IARC, OSHA or EU agencies
Mutagenicity / Reproductive Toxicity: Insufficient data for classification, avoid unnecessary exposure
Toxicity to Aquatic Life: May be toxic to aquatic organisms at sufficient concentrations
Persistence and Degradability: Not readily biodegradable, may persist in environment
Bioaccumulation Potential: Low to moderate, structure suggests possible bioconcentration in aquatic organisms
Mobility in Soil: Moderate water solubility implies some mobility if released
Other Adverse Effects: Potential for inhibition of microbial activity in soil and water
Avoid Release: Do not discharge into waterways, soil, or storm sewers
Disposal Methods: Dispose in accordance with local, regional, and national regulations as hazardous chemical waste
Container Disposal: Containers must be triple-rinsed, destroyed, and disposed of in licensed facility
Waste Treatment: Chemical incineration preferred, with gas scrubbing
Do Not: Dump into sewage systems, public water supplies, or soil
Code for Disposal: Use assigned waste code for chemical substances containing aminophenols
UN Number: Not classified as dangerous goods under UN regulations
Proper Shipping Name: 5-Amino-2-methylphenol, not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not expected, but avoid bulk release into marine setting
Special Transport Requirements: Keep container tightly closed, protected from extreme heat, handle as hazardous chemical in bulk shipments
Label Requirements: Chemical name and hazard pictograms if regulated under country-specific dangerous goods rules
Safety Assessment: Subject to chemical hazard communication regulations
TSCA Status (USA): Listed or notification provided
REACH (EU): Registration or pre-registration required for import above 1 tonne/year
EINECS: Listed under number 220-619-0
California Proposition 65: Not listed
Canadian DSL/NDSL: Present on DSL
Right-to-Know Listings: Some states require disclosure under worker safety laws
Labeling Requirements: Complies with GHS/CLP regulation, hazard symbols, and precautionary statements
SDS Revision Date: Provided on data sheet, regular updates encouraged for compliance
