Product Name: 4-Vinylphenol
Chemical Name: 4-Ethenylphenol
Synonyms: p-Vinylphenol, para-Vinylphenol
CAS Number: 2628-17-3
EC Number: 220-100-7
Recommended Use: Used in chemical synthesis, research, and as a flavor/fragrance intermediate
Supplier Information: Reach out to registered manufacturers or global chemical distributors for specific contact and emergency numbers.
Emergency Phone: Refer to supplier details on the packaging or safety signage.
GHS Classification: Flammable Liquid, Skin Irritant, Eye Irritant
Label Elements: Signal word DANGER, flame and exclamation mark pictograms
Hazard Statements: Highly flammable liquid and vapor, Causes skin irritation, Causes serious eye irritation
Precautionary Statements: Keep away from heat, sparks, open flames, and hot surfaces. Wear protective gloves and eye/face protection. Avoid breathing vapor.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Target Organs: Eyes, respiratory tract, skin
Acute Effects: Burning sensation, redness, coughing, nausea
Chronic Effects: Prolonged skin contact may lead to dermatitis
Chemical: 4-Vinylphenol
Concentration: Greater than 98% purity
Additives: No significant impurities known affecting classification
Impurities: May include trace phenolic compounds or unpolymerized material dependent on supplier
Molecular Formula: C8H8O
Molecular Weight: 120.15 g/mol
Inhalation: Move affected person to fresh air. Seek medical attention if symptoms persist. Use artificial respiration if necessary.
Skin Contact: Remove contaminated clothing and wash exposed area thoroughly with soap and water. Seek medical attention if irritation remains.
Eye Contact: Rinse eyes with plenty of water for at least 15 minutes. Remove contact lenses if present and continue rinsing. Get medical help if irritation continues.
Ingestion: Do not induce vomiting unless directed by medical personnel. Rinse mouth, give water if conscious. Consult poison control or doctor immediately.
Suitable Extinguishing Media: Use dry chemical powder, carbon dioxide, alcohol-resistant foam.
Unsuitable Media: Avoid water jet, which can spread the fire.
Special Hazards: Vapors can form explosive mixtures with air. Combustion yields carbon oxides and possibly toxic fumes.
Protective Equipment: Firefighters need self-contained breathing apparatus and full protective gear.
Firefighting Instructions: Evacuate area and fight fire from a safe distance. Cool exposed containers with water spray.
Personal Precautions: Evacuate area. Wear gloves, goggles, and suitable respiratory protection. Avoid contact and vapor inhalation.
Environmental Precautions: Prevent entry into drains and waterways. Contain spill with non-combustible absorbent (sand, earth).
Cleanup Methods: Collect spilled material in appropriate chemical waste containers. Wash spill area with water, ventilate area.
Disposal: Arrange for chemical disposal in compliance with local, state, and national regulations.
Safe Handling: Work in well-ventilated areas, use closed systems. Wear standard lab protective attire. Handle away from ignition sources.
Precautions: Avoid inhalation, ingestion, and contact with skin or eyes. Keep container tightly closed when not in use.
Storage Conditions: Store in cool, dry, well-ventilated area. Keep away from sunlight, incompatible materials (like strong oxidizers). Use only originally labeled containers.
Incompatibilities: Strong oxidizing agents, acids, bases, and direct sunlight.
Engineering Controls: Fume hood or local exhaust ventilation required. Safety showers and eyewash stations in proximity.
Exposure Limit: No established OSHA or ACGIH threshold limit value, but handle as a hazardous chemical.
Personal Protective Equipment: Chemical goggles, impervious gloves (like nitrile), lab coat. For high vapor, use organic vapor respirator.
Hygiene Measures: Do not eat, drink, or smoke around product. Wash hands after use.
Appearance: Colorless to pale yellow liquid or crystals
Odor: Distinct, sweet phenolic odor
pH: Not available
Melting Point: 30–34°C
Boiling Point: 220–225°C at atmospheric pressure
Flash Point: 100°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid and vapor
Vapor Pressure: 0.05 mmHg (20°C)
Solubility: Slightly soluble in water; soluble in most organic solvents
Vapor Density: 4.1 (air = 1)
Partition Coefficient: Log Kow 1.95
Autoignition Temperature: 480°C
Decomposition Temperature: Not determined
Chemical Stability: Stable under recommended conditions. Tends to polymerize if exposed to heat, light, or peroxides.
Hazardous Reactions: Reacts violently with strong oxidizers. Polymerization risk in presence of acids, alkalis, or light.
Conditions to Avoid: Open flames, heat, incompatible materials, and light.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, irritating phenolic fumes.
Acute Toxicity: Oral rat LD50 approximately 1800 mg/kg; can cause serious irritation through skin and eye exposure.
Skin Corrosion/Irritation: Causes moderate to severe irritation with prolonged contact.
Eye Damage/Irritation: Causes irritation, may cause burns at higher concentrations.
Respiratory Effects: Inhalation of vapors can lead to irritation of respiratory tract.
Chronic Effects: Long-term or repeated exposure may induce sensitization or dermatitis.
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA.
Mutagenicity & Reproductive Toxicity: No known reports.
Aquatic Toxicity: Moderately toxic to aquatic life (LC50/EC50 ranges from 10–100 mg/L for fish and daphnia).
Persistence & Degradability: Expected to biodegrade, but persists if released in large quantities.
Mobility in Soil: Likely to adsorb to organic matter, but some migration possible in groundwater.
Bioaccumulation: Low to moderate bioaccumulation potential (Log Kow <2).
Other Adverse Effects: Handling spills responsibly protects water sources and organisms in surrounding environments.
Waste Handling: Treat as hazardous chemical waste. Incinerate under controlled conditions or use licensed chemical disposal facilities.
Container Disposal: Triple rinse empty containers before disposal; puncture and send to hazardous waste landfill where permitted.
Legal Requirements: Comply with local, regional, and national regulations governing hazardous waste.
Best Practice: Store waste in clearly labeled, sealed containers. Do not dispose down the drain or release to the environment.
UN Number: UN 1993
Proper Shipping Name: Flammable Liquid, n.o.s. (4-Vinylphenol)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Labeling Requirements: Flammable liquid label needed.
Environmental Hazards: Not classified as marine pollutant but avoid transport with incompatible chemicals.
Special Precautions: Transport in tightly closed containers, away from heat sources and oxidizers.
TSCA: Listed on U.S. Toxic Substances Control Act Inventory.
REACH Status: Registration or notification in EU under REACH may apply.
SARA Title III: Not listed as an extremely hazardous or toxic chemical, but falls under general chemical reporting.
California Proposition 65: Not identified as carcinogenic or reproductively toxic in California.
WHMIS Classification (Canada): Classified as a hazardous substance under several categories.
Workplace Labeling: As required for flammable and irritant materials—ensure proper hazard communication.
Other Local Requirements: Refer to local chemical safety guidelines and environmental rules for storage, disposal, and reporting.
