Chemical Name: 4-Isopropyl-m-cresol
Synonyms: p-Isopropyl-m-cresol, Thymol
CAS Number: 3228-02-2
Recommended Use: Intermediate in organic synthesis, disinfectant
Supplier Information: Available on request from distributor
Emergency Contact Number: Refer to local safety department or product provider
Classification: Irritant to skin, serious eye irritant, possible respiratory tract irritant
GHS Label Elements: Signal word: Warning; Hazard pictograms: Exclamation mark
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation
Precautionary Statements: Wear protective gloves, wash skin thoroughly after handling, avoid inhaling dust or vapor, use only outdoors or in a well-ventilated area
Other Hazards: Not classified as flammable, can cause environmental effects if released in large amounts
Substance Name: 4-Isopropyl-m-cresol
Chemical Identity: C10H14O
Purity: Usually ≥98%, minor impurities may include organic byproducts
CAS Number: 3228-02-2
Relevant Impurities: Individual batches may contain trace levels of similar phenolic derivatives
General Advice: Move affected individual from exposure area, consult medical professional
Inhalation: Move to fresh air immediately, keep at rest, consult physician if symptoms persist
Skin Contact: Wash with soap and plenty of water for at least fifteen minutes, remove contaminated clothing
Eye Contact: Rinse thoroughly with plenty of water for several minutes, remove contact lenses if present
Ingestion: Rinse mouth with water, do not induce vomiting, get medical attention
Most Important Symptoms: Stinging, redness, irritation of eyes, skin irritation, sore throat from inhalation
Suitable Extinguishing Media: Use carbon dioxide, dry chemical powder, foam, or water spray
Special Hazards: May decompose under fire to phenolic vapors and carbon oxides, irritating fumes possible
Protective Equipment: Firefighters should use self-contained breathing apparatus, full protective gear
Advice for Firefighters: Move containers from fire area if it can be done safely, use water spray to cool
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, incomplete combustion products
Personal Precautions: Wear suitable protective equipment, avoid breathing vapors, prevent skin and eye contact
Environmental Precautions: Prevent product from entering drains, soil, waterways, alert local authorities if large spill occurs
Methods for Containment: Stop leak if it can be done safely, avoid dust formation, ventilate area
Methods for Cleanup: Collect spillage with non-combustible absorbent material (sand, earth, vermiculite), clean contaminated surfaces thoroughly with water and detergent
Reference to Other Sections: See disposal and protective measures for follow-up actions
Safe Handling: Use only in well-ventilated areas, avoid contact with skin, eyes, and clothing, do not breathe dust or vapor, wash hands thoroughly after handling
Safe Storage Conditions: Store tightly closed container in cool, dry, well-ventilated location, avoid direct sunlight, keep away from strong oxidizers and acids
Special Requirements: Store in original container, segregate from food and drink supplies
Incompatible Materials: Strong oxidizing agents, strong acids
Prevention of Accidental Release: Ensure proper secondary containment for larger quantities
Engineering Controls: Use local exhaust ventilation to control airborne exposure, secure eyewash station in vicinity
Personal Protective Equipment:
Respiratory: Use particulate respirator if airborne dust or vapor exceeds occupational exposure limits
Hand Protection: Wear chemical-resistant gloves (such as nitrile rubber)
Eye Protection: Safety goggles or face shield
Skin Protection: Protective clothing (lab coat, long sleeves)
Occupational Exposure Limits: Not established for this compound, consult workplace guidelines for phenolic compounds
Hygiene Measures: Remove contaminated clothing, wash before reuse, practice good personal hygiene
Appearance: White to off-white crystalline powder or solid
Odor: Characteristic phenolic, medicinal
Odor Threshold: Low, recognizable at low concentrations
pH: Slightly acidic to neutral in solution
Melting Point: 47°C to 51°C
Boiling Point: 233°C to 238°C
Flash Point: 123°C (closed cup)
Evaporation Rate: Not determined, low volatility
Flammability: Not considered highly flammable, but combustible at higher temperatures
Vapor Pressure: Very low at room temperature
Vapor Density: Heavier than air
Solubility: Low solubility in water, soluble in organic solvents (alcohol, ether)
Partition Coefficient (log Kow): Estimated moderate (due to hydrophobic isopropyl group)
Auto-ignition Temperature: Not determined
Decomposition Temperature: Above 200°C
Viscosity: Not applicable to solid form
Chemical Stability: Stable under recommended storage conditions, sensitive to strong oxidizers or acids
Conditions to Avoid: Excessive heat, improper storage, exposure to strong acids
Materials to Avoid: Strong oxidizing agents, strong acids, peroxide compounds
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, phenolic vapors
Possibility of Hazardous Reactions: Unlikely under normal handling, may react with oxidizing materials
Acute Toxicity: May cause harmful effects if swallowed, inhaled, or absorbed through skin
Skin Irritation: Causes redness, irritation, may cause dermatitis with repeated contact
Eye Damage: Strong irritant, causes pain, tearing, risk of corneal injury
Respiratory Sensitization: Upper respiratory tract irritation, cough, discomfort
Chronic Exposure Risks: Prolonged skin exposure may intensify irritation, risk of allergic reaction in sensitized individuals
Carcinogenicity: No data indicating carcinogenic effect; not listed by IARC, NTP, or OSHA
Mutagenicity: No available data to suggest mutagenicity
Reproductive Toxicity: No available data to indicate risk
Route of Exposure: Inhalation, skin contact, eye contact, ingestion
Aquatic Toxicity: Can be toxic to aquatic life in high concentrations, low water solubility reduces risk under normal use
Persistence and Degradability: Expected to undergo slow degradation, may persist in soil or sediment
Bioaccumulation: Low to moderate risk due to hydrophobic properties
Mobility in Soil: Limited, binds to soil particles
Other Effects: Avoid release into the environment, significant quantities may affect microorganisms
Waste Treatment Methods: Incinerate in approved facility, landfilling for small quantities in compliance with regulations
Product Disposal: Follow local, national, or regional regulations, do not release into drains
Contaminated Packaging: Dispose as hazardous waste, containers should be completely emptied and rinsed
Additional Notes: Consult local and state environmental authorities for guidance on disposal
UN Number: Not regulated as a hazardous material for most transport modes
UN Proper Shipping Name: No classification required
Transport Hazard Class: Not classified
Packing Group: Not assigned
Special Precautions: Keep container tightly closed, protect from physical damage
Environmental Hazards: Not designated as marine pollutant
Safety, Health, and Environmental Regulations: Not listed by REACH, TSCA (US), or other major chemical control inventories. Check country-specific regulatory status
Labelling Requirements: Hazard warnings required for workplace use
Other Relevant Legislation: Observe chemical safety workplace regulations, water act, waste act where applicable
Occupational Restrictions: Use in accordance with national and workplace directives for hazardous substances. Keep updated with regulatory changes
