Product Name: 4-Ethylguaiacol
Chemical Name: 4-Ethyl-2-methoxyphenol
CAS Number: 2785-89-9
Synonyms: p-Ethylguaiacol, 2-Methoxy-4-ethylphenol
Formula: C9H12O2
Recommended Use: Laboratory chemicals, flavor and fragrance research
Supplier: Laboratory supply company or authorized distributor
Contact Information: Emergency contact number, address of supplier
Classification: Flammable liquid, irritating to eyes and skin, may cause respiratory irritation
Signal word: Warning
Hazard Statements: Highly flammable liquid and vapor; Causes skin and eye irritation; May cause drowsiness or dizziness
Pictograms: Flame, exclamation mark
Precautionary Statements: Keep away from heat, sparks, and open flames; Wear protective gloves and eye/face protection; Handle with good ventilation
Health Effects: Short-term exposure may result in irritation from skin contact, reddening of eyes, or headaches from fumes
Environmental Effects: Toxic to aquatic life with long lasting effects
Chronic Exposure: Prolonged contact may cause dermatitis or respiratory sensitization in sensitive individuals
Chemical Identity: 4-Ethylguaiacol
CAS Number: 2785-89-9
Concentration: ≥98% (pure substance)
Impurities: Minor isomeric and process impurities less than 1% by weight
Additives: No stabilizers, allergens or preservatives intentionally added
Inhalation: Move to fresh air, keep at rest, seek medical attention if symptoms persist such as headache, nausea, dizziness
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, consult a physician for persistent irritation or rash
Eye Contact: Rinse cautiously with water for several minutes, remove any contact lenses, seek medical advice if irritation continues
Ingestion: Rinse mouth, do not induce vomiting, drink water, seek immediate medical help
Most Important Symptoms: Burning sensation, redness, coughing, difficulty breathing on inhalation of high concentrations
Special Advice for Doctors: Symptomatic treatment recommended based on clinical judgement, monitor for delayed respiratory effects
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray (small fires)
Unsuitable Extinguishing Media: Direct water jet, which may spread the fire
Specific Hazards: Produces carbon monoxide, carbon dioxide, and irritating fumes on combustion
Protective Equipment: Wear self-contained breathing apparatus and firefighting protective clothing including gloves and boots
Special Procedures: Evacuate area, fight fire from safe distance, cool exposed containers with water spray to prevent bursting
Explosion Risk: Vapors are heavier than air, may travel along ground and ignite from distant point
Personal Precautions: Evacuate non-essential personnel, ensure adequate ventilation, wear gloves, eye and face protection, use chemical-resistant footwear
Environmental Precautions: Prevent spillage from entering drains, sewers, or watercourses, contain spill with sand or earth
Cleanup Methods: Absorb with inert material like sand or vermiculite, sweep up carefully, place in labeled container for disposal, ventilate area thoroughly
Decontamination: Wash contaminated area with plenty of water after material is removed, collect washings for proper disposal
Other Advice: Dispose of collected material following local and national regulations for hazardous chemical waste
Handling: Handle in well-ventilated area, avoid breathing vapors or contact with skin and eyes, do not eat, drink or smoke when using product, wash thoroughly after use, avoid release to environment
Storage: Store in tightly closed original container, keep cool and dry, segregate from oxidizing agents, strong acids and bases, away from ignition sources, use explosion-proof equipment
Incompatibilities: Keep away from oxidizers, strong reducing agents, acids, alkalis
Storage Temperature: Room temperature, avoid heat and direct sunlight
Special Requirements: Use secondary containment trays to prevent accidental release in storage rooms
Engineering Controls: Local exhaust ventilation or chemical fume hood recommended, especially in confined or poorly ventilated areas
Exposure Limits: No established occupational exposure limits specifically for 4-ethylguaiacol, use limits for similar solvents as guidance
Respiratory Protection: Organic vapor respirator if exposure to vapors exceeds recommended limits or ventilation is inadequate
Hand Protection: Impervious protective gloves, such as nitrile or neoprene
Eye Protection: Safety goggles with side-shields or full-face shield
Skin Protection: Protective lab coat, chemical-resistant apron if risk of splashing
Hygiene Practices: Wash hands and exposed skin before eating, drinking, smoking or leaving work area, promptly remove contaminated clothing
Appearance: Clear to pale yellow liquid
Odor: Spicy, smoky, clove-like
Odor Threshold: Noticeable at very low concentrations, distinctive smell
pH: Not applicable (organic liquid)
Melting Point: -1 °C
Boiling Point: 227 °C
Flash Point: 87 °C (closed cup)
Evaporation Rate: Lower than water
Flammability: Flammable liquid, vapor forms explosive mixture with air
Vapor Pressure: 0.16 mmHg at 25 °C
Vapor Density: Heavier than air
Relative Density: 1.045 g/cm³
Solubility: Slightly soluble in water, miscible with organic solvents like ethanol, ether
Partition Coefficient (Log Kow): 2.3-2.8
Auto-ignition Temperature: 405 °C
Decomposition Temperature: Above 400 °C
Viscosity: Moderate, mobile liquid
Chemical Stability: Stable under recommended storage and normal temperature conditions
Reactivity: Not reactive with most materials under standard conditions
Incompatible Materials: Strong oxidizers such as peroxides, nitric acid, concentrated sulfuric acid, strong alkalies
Hazardous Decomposition: Carbon monoxide, carbon dioxide, and phenolic fumes on thermal decomposition
Polymerization: Does not polymerize spontaneously
Conditions to Avoid: Heat, sparks, open flames, static discharge
Acute Toxicity: LD50 (oral, rat) estimated above 1500 mg/kg
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Effects: Drowsiness, dizziness, nausea, eye and respiratory tract irritation, nausea with large ingestions
Skin Irritation: Causes mild to moderate irritation, prolonged exposure can worsen effects
Eye Irritation: Causes eye discomfort, redness, and tearing
Chronic Toxicity: May cause contact dermatitis, repeated exposure can sensitize skin
Carcinogenicity: No information supporting any carcinogenic effect for 4-ethylguaiacol
Germ Cell Mutagenicity: Not considered mutagenic in available studies
Reproductive Toxicity: No data indicating reproductive risk at low-level exposure
Sensitization: Some individuals may become sensitized after repeated skin contact
Other Information: Not listed by IARC, NTP, OSHA as carcinogenic
Ecotoxicity: Harmful to aquatic organisms, may cause long-term adverse effects in aquatic environments
Persistence/Degradability: Expected to be biodegradable, moderate environmental persistence
Bioaccumulative Potential: Potential for low to moderate bioaccumulation (Log Kow 2.3-2.8)
Mobility: Low mobility in soil due to moderate water solubility, likely to partition into organic matter
Aquatic Toxicity: LC50 (fish, 96h): 10-100 mg/L (estimated)
Warnings: Prevent bulk material release to waterways, follow best practices for wastewater treatment
Waste Disposal: Collect and store waste in tightly closed, clearly labeled chemical containers
Methods: Hand over to a licensed specialty chemical disposal contractor
Incineration: Suitable for combustion at approved incineration facilities with after-burners and scrubbing
Precautions: Do not pour into drains or public sewage, do not landfill untreated residues
Packaging Disposal: Rinse empty containers, dispose as hazardous waste following local requirements
Regulatory References: Follow applicable regional, national, and local environmental waste management authority guidelines
UN Number: 1993
Proper Shipping Name: Flammable liquid, n.o.s. (contains 4-Ethylguaiacol)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: III (minor hazard)
Label Required: Flammable liquid
Special Precautions: Avoid transport with incompatible goods, keep containers upright and secure during transit, follow all local and international requirements
Environmental Hazards: Marine pollutant
Transport Provisions: Emergency information for accidental spillage must accompany shipment
OSHA Status: Classified as hazardous under OSHA Hazard Communication Standard
TSCA: Listed on Toxic Substances Control Act inventory
SARA Title III: Not subject to emergency planning or community right-to-know reporting
REACH Registration: Compliant with REACH requirements for laboratory chemicals
GHS Compliance: GHS labeling and classification followed
Other Regulations: Subject to state-specific right-to-know, workplace risk assessment and control, international hazard communication rules
Workplace Exposure: Refer to national occupational safety acts for legal exposure limits and safety training
Consumer Use: Not intended for public use; professional handling recommended under controlled conditions
