Product Name: 4-Chloroacetylcatechol
Synonyms: 3,4-Dihydroxyphenylchloroacetyl, 2-Chloro-1-(3,4-dihydroxyphenyl)ethanone
Chemical Formula: C8H7ClO3
CAS Number: 77876-66-9
Recommended Use: Laboratory chemical, chemical synthesis intermediate
Supplier Details: Chemical supply distributor information required per transaction
Emergency Contact: CHEMTREC: 1-800-424-9300
Classification: Acute Toxicity (Oral), Skin Irritation, Eye Irritation, Specific Target Organ Toxicity (Single Exposure)
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes skin and eye irritation.
Precautionary Statements: Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Pictograms: Exclamation mark
Effects of Overexposure: May cause dizziness, nausea, burning or stinging sensation upon contact with eyes or membrane surfaces
Routes of Entry: Ingestion, skin, eye contact, inhalation of dusts
Chemical Name: 4-Chloroacetylcatechol
Purity: >98%
Impurities: Trace solvents <2% (methanol, remains of synthesis), traces of unreacted precursor
Ingredient Weight %: 100%
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes. Remove contact lenses. Seek medical advice.
Skin Contact: Remove contaminated clothing. Wash skin with soap and water for minimum 15 minutes. Seek medical attention if irritation persists.
Inhalation: Move person to fresh air. Support breathing with oxygen if needed. Get medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting. Get medical help quickly.
Signs and Symptoms: Stinging eyes, redness, cough, skin irritation, headache, nausea
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Media: Do not use strong water jet
Hazards: Emits toxic fumes (hydrochloric acids, carbon oxides) if burned
Protective Equipment: Firefighters use self-contained breathing apparatus and chemical protective clothing
Special Procedures: Contain runoff with barriers, avoid contamination into drains or water supplies
Personal Protection: Use chemical-resistant gloves, goggles, respirator (if dust possible), lab coat
Environmental Precautions: Keep out of drains, surface water, or soil
Spill Cleanup: Ventilate area. Absorb spills with inert material (vermiculite, sand). Collect residue in labeled container. Wash spill site after material pick-up is complete.
Disposal: Follow Section 13 regulations for proper chemical waste removal
Handling: Avoid breathing dust. Use only in well-ventilated areas or fume hood. Prevent contact with eyes, skin, clothing. Use proper PPE (protective personal equipment).
Storage: Store tightly closed in a cool, dry, well-ventilated area. Store away from incompatible substances (oxidizers, bases). Keep container upright and clearly labeled. Keep away from ignition sources. Avoid humidity.
Workplace Exposure Limits: No established OSHA/ACGIH PEL/TLV, minimize exposure according to good manufacturing practice
Engineering Controls: Use local exhaust, fume hoods, eyewash and emergency shower equipment
Personal Protection: Chemical-resistant gloves (nitrile or PVC), full splash goggles, long sleeves, lab coat, NIOSH-approved respirator if dust or vapors expected
Hygiene Measures: Wash hands and face after handling. Do not eat, drink, or smoke in lab areas.
Environmental Controls: Prevent emission of dust/fumes via sealed process/vacuum methods
Physical State: Crystalline solid
Color: Usually white to pale beige
Odor: Faint phenolic
Molecular Weight: 186.59 g/mol
Melting Point: 109 - 113°C
Boiling Point: Decomposes before boiling
Solubility: Partially soluble in water, soluble in methanol, ethanol, dimethyl sulfoxide
Vapor Pressure: Not data available
Density: 1.5–1.6 g/cm³
pH: Not available (for solid), slightly acidic in solution
Partition Coefficient (log Kow): Not established
Flash Point: Not established
Autoignition Temperature: Not available
Chemical Stability: Stable under recommended storage conditions
Reactivity: Non-reactive under normal procedures; reacts with strong oxidizers, strong bases
Hazardous Reactions: May release HCl gas or irritating fumes on strong heating or mixing with acids
Hazardous Decomposition: Hydrochloric acid, carbon oxides, small quantities of chlorine
Incompatibilities: Strong oxidizing agents, strong alkali, reducing agents
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Toxicity: Oral LD50 (rat): Not determined. Harmful if swallowed.
Chronic Toxicity: Data not available for repeated dose effects
Skin/Eye Irritation: Causes irritation based on structure and related substances
Sensitization: No data
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity / Teratogenicity: Not tested, related catechols can show mutagenic potential at high doses
Other Information: Catechols sometimes cause allergic reactions in sensitive individuals
Toxicity to Fish/Invertebrates: Not directly tested, but aromatic chloro-ketones show moderate toxicity to aquatic organisms
Persistence/Degradability: Stable in environment, slow natural degradation expected
Bioaccumulative Potential: Potential for low-moderate based on logP of related compounds
Mobility in Soil: May leach with water but binds to organic matter
Other Harmful Effects: Avoid uncontrolled release due to possible adverse effects on aquatic life, especially invertebrates
Product Disposal: Dispose of unused chemical as hazardous waste according to local, national, and federal regulations. Small quantities safely neutralized using appropriate professional methods.
Contaminated Packaging: Containers must be triple rinsed and then disposed as hazardous waste.
Additional Procedures: Never discharge into the environment or municipal drains
UN Number: Not classified for bulk transport under UN/IMDG/IATA for general shipment
Shipping Name: Laboratory chemicals, n.o.s.
Transport Hazard Class: Not regulated as dangerous goods
Packing Group: Not regulated
Special Precautions: Avoid extreme temperatures, strong impact, and rough handling. Use firm secondary containment.
OSHA Status: Not specifically listed
TSCA Inventory: Check lot-specific status with supplier
SARA Title III (Sections 302, 311/312, 313): Not subject to reporting under normal conditions
DSL/NDSL (Canada): Check with supplier per batch
REACH (EU): Low-volume, not registered at this time
WHMIS Classification (Canada): Not classed
California Proposition 65: Not listed
Other National Inventories: Check current status by region if needed for import/export
