Product Name: 4-Chloro-O-Cresol
Chemical Name: 4-Chloro-2-methylphenol
Synonyms: Para-chloro-o-cresol, PCMC
CAS Number: 1570-64-5
Recommended Uses: Antimicrobial agent, disinfectant, preservative
Manufacturer Contact: [Refer to supplier details on packaging]
Emergency Contact: [Refer to regulatory reporting requirements]
Classification: Acute Toxicity (oral, dermal, inhalation), Eye Irritation, Skin Corrosion/Irritation
GHS Label Elements: Danger, skull and crossbones pictogram, exclamation mark, corrosive
Hazard Statements: Causes severe skin burns and eye damage; Harmful if swallowed, in contact with skin, or inhaled
Precautionary Statements: Avoid inhalation, wear protective gloves/clothing/eye protection, wash exposed skin thoroughly
Potential Health Effects: Irritation to eyes, skin, respiratory tract; May cause symptoms like burning sensation, coughing, headache, nausea
Signal Word: Danger
Chemical: 4-Chloro-2-methylphenol
CAS Number: 1570-64-5
Concentration: ≥ 98% (typically pure substance)
Impurities: Possible trace levels of related chlorophenols or methylphenols, as per technical grade
Molecular Formula: C7H7ClO
Molecular Weight: 142.58 g/mol
Inhalation: Move person to fresh air. If breathing difficulties arise, provide oxygen, seek medical advice.
Skin Contact: Remove contaminated clothing, rinse affected body parts with running water for at least 15 minutes, consult a physician if irritation occurs.
Eye Contact: Rinse immediately with plenty of water for at least 15 minutes, lifting eyelids. Consult an ophthalmologist at once.
Ingestion: Rinse mouth with water, do not induce vomiting, get medical help immediately. Never give anything by mouth to an unconscious person.
Additional Information: Show MSDS or product label to healthcare workers. Monitor for symptoms of toxicity and provide symptomatic support.
Suitable Extinguishing Media: Use dry chemical, CO2, foam, or water spray. Avoid direct streams of water if possible.
Hazardous Combustion Products: Irritating fumes, hydrochloric acid, phenol derivatives, carbon monoxide, carbon dioxide
Firefighting Instructions: Wear full protective clothing and self-contained breathing apparatus. Approach from upwind to avoid hazardous fumes.
Special Hazards: Vapors are heavier than air and may travel to ignition sources. Avoid dust formation. Chemical runoff may contaminate water supplies.
Explosion Hazards: May produce toxic or corrosive vapors under fire conditions.
Personal Precautions: Isolate spill area, evacuate unnecessary personnel, wear chemical-resistant gloves, eye protection, and suitable clothing. Avoid breathing vapors or dust.
Environmental Precautions: Prevent entry into drains, sewers, basements, waterways
Methods for Cleaning Up: Absorb spill with inert material (sand, earth, vermiculite), place in chemical waste container for local disposal. Wash spill area with water after material pickup.
Note: Use non-sparking tools for cleanup. Ventilate affected area.
Handling: Wear suitable PPE, wash hands and exposed skin after use. Avoid all contact with eyes, skin, and clothing. Prevent inhalation of dust, mist or vapor. Keep product containers tightly closed.
Storage: Store in a cool, dry, well-ventilated area away from incompatible substances including oxidizers, acids, and strong bases. Keep container tightly sealed to avoid moisture intake and contamination.
Incompatibilities: Acids, bases, oxidizing agents, and strong reducing agents
Exposure Limits: No specific OSHA/NIOSH PEL established. Employers should set workplace limits based on risk assessment and good industrial hygiene.
Engineering Controls: Local exhaust ventilation, general dilution ventilation recommended to minimize airborne levels.
Personal Protective Equipment:
– Eyes: Chemical goggles or face shield
– Skin: Suitable chemical-resistant gloves (nitrile, neoprene), long-sleeved clothing
– Respiratory: Approved respirators (P95 or better) if airborne levels are high
– Other: Eyewash station and emergency shower in work area
Appearance: White to off-white crystalline powder
Odor: Phenolic, medicinal
pH: 5.5–6.5 (1% aqueous solution)
Melting Point: 86–89°C
Boiling Point: 246°C
Flash Point: Above 120°C (closed cup)
Solubility: Slight in water; easily soluble in organic solvents such as ethanol, ether
Vapor Pressure: Low at room temperature (estimated 0.008 mmHg at 25°C)
Density: 1.29 g/cm3
Partition Coefficient (log Kow): 2.3
Chemical Stability: Remains stable under normal storage and handling conditions.
Reactivity: Can react with oxidizers, acids, bases. Product breaks down at high temperatures to release toxic gases.
Possibilities of Hazardous Reactions: Exothermic reactions with bases and strong oxidizing agents.
Decomposition Products: Phenol derivatives, chlorine compounds, carbon monoxide, carbon dioxide.
Conditions to Avoid: Heat, sunlight, moisture, storage with incompatible materials.
Acute Toxicity (Oral): LD50 (rat): ~ 183 mg/kg
Acute Toxicity (Dermal): LD50 (rabbit): ~ 850 mg/kg
Acute Toxicity (Inhalation): Data limited, expect toxicity with airborne dusts.
Skin Corrosion/Irritation: Causes severe burns; irritation and redness common.
Eye Damage/Irritation: Corrosive; permanent damage possible.
Sensitization: Possible skin sensitizer on prolonged or repeated contact.
Chronic Effects: May cause liver and kidney damage, CNS symptoms with high exposures.
Mutagenicity/Carcinogenicity: Not classified as carcinogenic by IARC, OSHA, or NTP.
Other Symptoms: Headache, dizziness, nausea, difficulty breathing after acute exposure.
Toxicity to Aquatic Life: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. LC50 (fish, 96h): ~2 mg/L
Persistence and Degradability: Moderately persistent; breaks down slowly by biodegradation in soil and water.
Bioaccumulation Potential: Moderate potential for bioaccumulation (log Kow = 2.3).
Mobility in Soil: Limited due to low water solubility.
Other Ecological Notes: Prevent release to surface water, soil, or groundwater. Fish and aquatic invertebrates especially susceptible.
Waste Disposal: Treat chemical and contaminated packaging as hazardous waste. Incineration preferred in chemical incinerator equipped with afterburner and scrubber.
Disposal Containers: Use tightly closed, properly labeled chemical waste drums/containers.
Environmental Precautions for Disposal: Do not discharge to sewer or waterways.
Regulatory Compliance: Dispose according to federal, state, and local regulations concerning hazardous chemicals.
Additional Instructions: Contact licensed waste disposal services for appropriate guidance on handling and permitted disposal methods.
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (4-Chloro-O-Cresol)
Transport Hazard Class: 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Labels: Environmentally hazardous, Class 9
Marine Pollutant: Yes
Special Precautions: Avoid shipping in large bulk containers without secondary containment. Comply with all packaging and labeling requirements.
TSCA: Listed on U.S. Toxic Substances Control Act inventory
REACH Status (EU): Registered substance under European REACH regulations
SARA Title III: Not specifically listed as hazardous, but reportable for large releases
OSHA Hazard Communication Standard: Hazardous chemical
California Prop 65: Not listed
WHMIS Classification (Canada): D2B—Toxic material
Other Regulatory Data: Subject to workplace monitoring and environmental release prevention under community health and safety laws
