Product Name: 4-Chloro-3,5-Xylenol
Chemical Name: 4-Chloro-3,5-dimethylphenol
Other Names: PCMX, para-chloro-meta-xylenol
CAS Number: 88-04-0
Recommended Use: Antiseptic, disinfectant, preservative
Supplier Information: Contact details for manufacturer or distributor include company name, address, phone number, emergency contact details.
Classification: Irritant; harmful if swallowed; risk of serious damage to eyes and skin.
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; harmful if inhaled or ingested; can cause respiratory irritation.
Precautionary Statements: Wear protective gloves and eye protection; avoid breathing dust or fumes; wash thoroughly after handling.
GHS Pictograms: Exclamation mark; Health hazard
Target Organs: Skin, eyes, respiratory tract.
PPE Required: Goggles, chemical-resistant gloves, lab coat.
Chemical Component: 4-Chloro-3,5-Xylenol
Chemical Formula: C8H9ClO
Concentration: 99% or greater purity in technical grade; may contain low levels of related aromatic impurities.
Impurities: Trace levels of 3,5-dimethylphenol, other substituted phenols noted in analytical reports.
Inhalation: Move person to fresh air. Provide oxygen if breathing difficulty occurs. If symptoms persist, seek medical attention.
Skin Contact: Wash affected area with soap and water for at least 15 minutes. Remove contaminated clothing and launder before reuse.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing and get medical advice.
Ingestion: Rinse mouth, drink water if subject is conscious, do not induce vomiting. Call poison control or physician.
Most Important Symptoms/Effects: Irritation, redness, burning feeling in contact area. In severe cases, severe respiratory distress or systemic effects possible.
Emergency Medical Attn: Recommended for eye exposure, major ingestion, or breathing difficulty.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide.
Unsuitable Media: Direct water jet may spread chemical.
Specific Hazards: Thermal decomposition releases toxic fumes of hydrogen chloride, carbon monoxide, and chlorinated organics.
Fire-fighting Procedures: Use self-contained breathing apparatus; fight fire from safe distance, use protective clothing.
Hazardous Combustion Products: Phenolic vapors, chlorine compounds.
Special PPE: Full gear with respiratory protection required for fire environment.
Explosion Data: Dust can generate explosive mixtures when suspended in air under rare circumstances.
Personal Precautions: Evacuate area; provide ventilation; avoid breathing dust.
Protective Equipment: NIOSH-approved respirator, gloves, goggles, and chemical-resistant apron.
Emergency Procedures: Prevent further leakage or spillage; control dust formation.
Containment: Stop leak if safe. Surround spill with absorbent material (vermiculite, sand).
Cleanup Methods: Carefully collect spilled material. Transfer to a container for disposal. Clean area with water and detergent.
Environmental Precautions: Do not release to sewers or waterways; notify authorities if significant spill occurs.
Handling: Avoid contact with skin, eyes, and clothing. Do not breathe dust or fumes. Wash hands thoroughly after use. Provide adequate ventilation in work area.
Storage: Store in a tightly closed container away from incompatible materials such as oxidizers and acids. Keep in a cool, dry, and well-ventilated place. Protect from direct sunlight and moisture.
Incompatibilities: Strong oxidizers, acids, bases. Contact may produce hazardous gases.
Storage Conditions: Temperature stability between 5°C and 30°C optimal for preservation of material quality. Label all containers clearly. Ensure secondary containment for bulk storage.
Safe Transfer Methods: Use grounded equipment to prevent static buildup. Avoid handling near ignition sources due to dust risk.
Occupational Exposure Limits: No OSHA PEL or ACGIH TLV specifically assigned; minimize as low as reasonably achievable.
Engineering Controls: Use fume hoods, local exhaust ventilation. Monitor air for dust.
Personal Protection: Nitrile gloves, safety goggles, lab coat, and, if required, face shield.
Respiratory Protection: Dust mask or half-mask respirator for powder handling or low-level vapor exposure.
Hygiene Measures: No eating, drinking, or smoking in work areas. Wash hands and face after handling.
Environmental Controls: Spill containment, regular facility cleaning, and proper air flow necessary.
Appearance: White to faintly yellow crystalline powder
Odor: Slight phenolic
Odor Threshold: Not established
pH: Approx. 6 (1% aqueous solution)
Melting Point: 114°C to 116°C
Boiling Point: 246°C
Flash Point: 163°C
Evaporation Rate: Not applicable
Flammability: May ignite at high temperature
Vapor Pressure: Very low at standard temperature
Vapor Density: Not available
Relative Density: About 1.22 (water = 1)
Solubility: Slightly soluble in water; freely soluble in alcohol and many organic solvents
Partition Coefficient (log Kow): 3.4
Auto-ignition Temperature: Not determined
Decomposition Temperature: Data not fully established
Viscosity: Not relevant for solid.
Chemical Stability: Stable under recommended storage and handling conditions.
Reactivity: Reacts with strong acids or bases, reacts with oxidizing agents.
Hazardous Reactions: Violent chemical reaction possible with incompatible materials.
Hazardous Decomposition: Phenol vapors, hydrogen chloride, carbon oxides.
Conditions to Avoid: High humidity, direct sunlight, open flames, static discharge.
Incompatible Materials: Strong oxidizers including chlorine, nitric acid, peroxides.
Polymerization: Does not undergo hazardous polymerization under normal conditions.
Routes of Exposure: Inhalation, ingestion, skin and eye contact.
Acute Toxicity: Oral LD50 (rat): around 3830 mg/kg
Skin Irritation: Moderate to severe in animal studies
Eye Irritation: Causes serious eye damage
Respiratory Irritation: Possible, especially if powders are inhaled
Chronic Exposure Risks: Prolonged or repeated exposure can cause dermatitis, damage to target organs such as liver if absorbed in large amounts.
Sensitization: Sensitization reactions reported rarely
Carcinogenicity, Mutagenicity, Reproductive Toxicity: Insufficient evidence available; not listed as carcinogen by IARC, NTP, OSHA
Ecotoxicity: Toxic to aquatic organisms; LC50 (fish, 96hr): 1.67 mg/L (Oncorhynchus mykiss).
Persistence and Degradability: Moderately biodegradable under environmental conditions; can persist in soil or water under anaerobic circumstances.
Bioaccumulative Potential: Log Kow value indicates moderate possibility for bioaccumulation.
Mobility in Soil: Low to moderate mobility; some leaching possible depending on soil type.
Other Harmful Effects: Do not allow unneutralized material into environment.
Aquatic Toxicity: Toxic to some forms of algae and bacteria even at low concentrations.
Waste Treatment Methods: Consult local, regional, and national requirements for hazardous waste disposal.
Product Disposal: Handled as hazardous organic waste. Incineration preferred in approved facility.
Contaminated Packaging: Dispose of as hazardous waste. Triple rinse then offer drum for recycling or disposal.
Special Precautions: Do not discharge into drains, waterways, or environment. Report spill as necessary.
Methods for Neutralization: Neutralize externally with sodium bicarbonate or calcium hydroxide under controlled conditions before final disposal.
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains 4-Chloro-3,5-xylenol)
Transport Hazard Class: 9
Packing Group: III
Labels Required: Environmentally hazardous, miscellaneous dangerous goods
Special Precautions for User: Transport in sealed, labelled containers with adequate protection against breakage.
International Transport: IMO, IATA, ADR regulations classify as hazardous.
Reportable Quantity: May be required to notify authorities for large releases.
US Federal Regulations: Listed under TSCA inventory. Not specifically regulated as a carcinogen or reproductive toxin.
OSHA: Not classified as highly hazardous, general duty applies.
SARA Title III: Section 311/312 - Acute health, chronic health hazard.
EPA: Regulated as hazardous waste under RCRA; subject to reporting under CERCLA for large releases.
EU Regulations: Listed under REACH registration; subject to use restrictions in biocidal products.
Canada WHMIS: Classified as toxic and irritant; may require workplace training and labeling.
Other Requirements: National, state, and local rules may also apply based on facility size and use.
Label Requirements: Product must carry hazard warning, precautionary instructions, and supplier identification.
