Product Name: 4-Butylresorcinol
Chemical Name: 4-Butyl-1,3-benzenediol
CAS Number: 18979-61-8
Synonyms: 4-n-Butylresorcinol, Butylresorcinol
Use: Used as an active ingredient in skin brightening formulas, cosmetic products, research and development.
Supplier: Chemical manufacturers or distributors in specialty chemicals sector.
Emergency Telephone: Consult regional Poison Control Centers or local emergency numbers for prompt guidance.
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Hazardous to aquatic environment (Category 3).
Pictogram: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation, harmful to aquatic life.
Precautionary Statements: Avoid breathing dust or vapors, wash thoroughly after handling, use protective equipment, prevent release to environment, seek medical advice after exposure.
Routes of Entry: Inhalation, skin and eye contact, ingestion.
Symptoms: Redness, swelling, discomfort, breathing difficulty if inhaled as dust.
Chemical Identity: 4-Butylresorcinol
Concentration: >98%
Molecular Formula: C10H14O2
Molecular Weight: 166.22 g/mol
Impurities: Trace organic by-products & residual solvents may occur at <2%.
Inhalation: Move exposed person to fresh air, seek medical attention if symptoms persist, provide artificial respiration if not breathing.
Skin contact: Remove contaminated clothing, wash area thoroughly with plenty of soap and water, seek medical help if irritation develops.
Eye contact: Rinse immediately with plenty of water for 15 minutes, hold eyelids apart, remove contact lenses if present, seek medical advice.
Ingestion: Do not induce vomiting, rinse mouth out with water, get medical attention promptly.
Most Important Symptoms: Irritation to mucous membranes, nausea, headache possible from heavy exposure, allergic reactions in sensitive individuals.
Suitable Extinguishing Media: Carbon dioxide, extinguishing powder, foam, water spray.
Unsuitable Media: High pressure water streams might spread product.
Hazardous Combustion Products: Carbon oxides, toxic vapors, phenolic compounds.
Protective Equipment: Self-contained breathing apparatus, full protective gear.
Fire Hazards: Can form explosive dust/air mixtures, emits toxic fumes if involved in fire, containers may rupture in heat.
Special Precautions: Cool fire-exposed containers with water, avoid inhalation of smoke, evacuate area if large fire ensues.
Personal Precautions: Avoid contact with skin, eyes, and clothing, use appropriate PPE, ventilate area.
Environmental Precautions: Prevent spillage from entering drains, surface waters, soil.
Cleanup Methods: Absorb spilled material with inert substance (sand, earth), collect for disposal in sealed container, decontaminate area with detergent.
Notification: Report significant spills to environmental authorities according to local requirements.
Handling: Avoid exposure by minimizing dust and direct contact, use only under well-ventilated conditions, prevent accumulation of dust on surfaces.
Hygiene: Wash hands before breaks and after handling, keep working clothes separate.
Storage Conditions: Keep container tightly closed in a cool, dry, well-ventilated place, away from direct sunlight and sources of ignition, segregate from incompatible materials like strong oxidizers.
Packing Materials: Use containers that resist chemical attack, clearly labeled to prevent mix-up.
Engineering Controls: Handle under exhaust ventilation, use protective enclosures for processes generating dust.
Occupational Exposure Limit: No established ACGIH, OSHA, or NIOSH values for pure substance—control exposure as for other low-volatility phenolic compounds.
Personal Protective Equipment: Safety glasses with side shields or goggles, chemical-resistant gloves (nitrile recommended), lab coat or coveralls, NIOSH approved respirator in absence of adequate ventilation.
Environmental Protection: Use spill containment and proper waste management systems in storage and handling areas.
Appearance: White to off-white solid or crystalline powder.
Odor: Mild, slightly phenolic.
Odor Threshold: Not available.
pH: Slightly acidic in solution.
Melting Point: 86-90°C.
Boiling Point: 296-298°C.
Flash Point: >130°C (closed cup).
Evaporation Rate: Not applicable.
Explosive Limits: Not established.
Vapor Pressure: Low at room temperature.
Solubility: Slightly soluble in water, soluble in ethanol, DMSO.
Partition Coefficient (log Pow): 2.2 (estimated).
Autoignition Temperature: Decomposes above 430°C.
Decomposition Temperature: Above 200°C.
Density: 1.1–1.2 g/cm³.
Stability: Stable under ordinary storage and handling conditions away from incompatible substances.
Reactivity: Non-reactive under recommended usage.
Incompatible Materials: Strong oxidizers, acids, alkalis, peroxides.
Hazardous Decomposition: Produces carbon monoxide, carbon dioxide, and other toxic fumes under fire conditions.
Polymerization: Not expected to occur.
Acute Toxicity: Oral LD50 (rat) estimated at >2,000 mg/kg.
Skin Corrosion/Irritation: Causes irritation on prolonged or repeated exposure.
Serious Eye Damage/Irritation: Causes significant eye irritation.
Respiratory Sensitization: Sensitization not expected, dust can irritate airways.
Skin Sensitization: May provoke allergic response in susceptible individuals.
Mutagenicity/Carcinogenicity: No data proving mutagenic or carcinogenic activity.
Reproductive Toxicity: No studies identifying risk.
Chronic Effects: Long-term exposure may increase dermatitis risk.
Ecotoxicity: Harmful to aquatic organisms at high concentrations, avoids discharge to sewers and water bodies.
Persistence and Degradability: Slowly biodegradable, persistent in poorly aerated water.
Bioaccumulation: Moderate potential for accumulation in aquatic organisms due to log Pow.
Mobility in Soil: Low mobility, binds strongly to soil materials.
Other Adverse Effects: Large quantities may compromise effluent quality.
Disposal Methods: Collect residue in tightly closed containers, incinerate at approved chemical waste facility, avoid landfill disposal whenever possible.
Waste Code: Depending on admixture, classify under local and national waste regulations.
Contaminated Packaging: Rinse thoroughly before disposal or offer for recycling as appropriate.
Precautions: Wear suitable protective equipment, do not permit release to the environment.
UN Number: Not regulated as dangerous for transportation by air, land, or water.
UN Proper Shipping Name: Not applicable.
Transport Hazard Class: Not classified.
Packing Group: Not classified.
Environmental Hazards: Avoid large releases, transport in sealed containers.
Special Precautions: Protect containers from physical damage and extreme weather.
TSCA Status: Listed or accepted for commercial use in the United States.
EU REACH: Registered under applicable registration numbers, ensure compliance with supply chain obligations.
GHS Labeling: Required for laboratory and industrial uses as described.
SARA 313: Not listed as a toxic chemical.
California Proposition 65: Not classified as carcinogen or reproductive toxin.
Other Regulations: Check national and regional chemical safety legislations for handling, reporting, and use.
