Product Name: 4-Bromocatechol
Chemical Formula: C6H5BrO2
CAS Number: 1675-61-6
Synonyms: 4-Bromo-1,2-benzenediol
Manufacturer: Supplier details should always be verified before ordering and handling.
Recommended Use: Research, laboratory reagent, synthesis in specialty chemical manufacturing.
GHS Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin irritation
Hazard Symbols: Exclamation mark, Health hazard
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, can cause respiratory discomfort with prolonged exposure.
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves and eye protection, avoid breathing dust or vapor, use personal protective equipment as required.
Chemical Name: 4-Bromocatechol
Purity: ≥98%
CAS Number: 1675-61-6
EC Number: 216-849-3
Impurities: Trace amounts of isomers and brominated impurities unlikely to exceed 1% total.
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, seek medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing, wash affected area with soap and water for at least 15 minutes, seek medical help if irritation or redness remains.
Eye Contact: Rinse eyes immediately with plenty of water for at least 15 minutes, keep eyelids open, consult an eye specialist if discomfort continues.
Ingestion: Do not induce vomiting, rinse mouth thoroughly with water, give water to drink if the person is conscious, seek immediate medical attention.
General Advice: Always get medical advice after significant exposure, bring the chemical label when seeking medical help.
Suitable Extinguishing Media: Use water spray, dry chemical powder, alcohol-resistant foam, or carbon dioxide.
Unsuitable Extinguishing Media: Do not use high-pressure water jets.
Special Hazards: Emits toxic fumes of hydrogen bromide, carbon monoxide, carbon dioxide, and phenolic vapors under fire conditions.
Advice for Firefighters: Wear self-contained breathing apparatus, full protective clothing, avoid skin/eye contact with fire runoff.
Precautions: Fight fire from upwind to avoid inhaling hazardous vapors.
Personal Precautions: Evacuate unnecessary personnel, ventilate area, wear appropriate protective equipment.
Environmental Precautions: Do not let material enter sewers, drains, surface water, or soil, contain spillage using inert absorbent.
Cleanup Methods: Scoop up and collect spilled substance in suitable, labeled containers using non-sparking tools, clean area with large amounts of water.
Disposal Considerations: Dispose of according to local, regional, national, and international regulations, minimize environmental release.
Handling: Minimize dust generation and accumulation, avoid contact with skin, eyes, and clothing, do not breathe dust, use only in well-ventilated areas with fume extraction.
Storage: Store locked up in a tightly closed container, keep container in a well-ventilated, dry, cool area away from incompatible substances such as strong oxidizing agents and bases.
Incompatible Materials: Bases, strong oxidizers, heat sources.
Hygiene Practices: Wash thoroughly after handling, remove contaminated clothing and launder before reuse.
Control Parameters: No established workplace exposure limits, handle as potentially hazardous, keep exposure as low as possible.
Engineering Controls: Use chemical fume hood, ensure good general ventilation.
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), fitted safety goggles or face shield, laboratory coat, suitable respiratory protection if airborne concentrations exceed safe levels.
Environmental Protection: Prevent release to environment using containment, regular monitoring for leaks or spills.
Appearance: White to off-white crystalline solid
Odor: Phenolic, faint
Odor Threshold: Not determined
pH: Not applicable (insoluble in water at neutral pH)
Melting Point: 163-167°C
Boiling Point: Decomposes before boiling
Flash Point: Not highly flammable
Solubility: Partially soluble in water, soluble in ethanol, acetone, and common organic solvents
Vapor Pressure: Negligible at room temperature
Density: Approx. 1.88 g/cm3
Partition Coefficient (log Kow): Estimated 1.5-2.1
Autoignition Temperature: Not determined
Decomposition Temperature: >200°C
Viscosity: Not applicable (solid)
Chemical Stability: Stable at room temperature under recommended storage conditions.
Reactivity: Can react with strong oxidizing agents, may undergo halogen exchange.
Hazardous Reactions: No dangerous reactions known under normal conditions, avoid strong bases and oxidizers to prevent possible decomposition.
Decomposition Products: Toxic gases like hydrogen bromide, carbon monoxide, carbon dioxide, and other brominated compounds.
Conditions to Avoid: Heating, strong light, moisture, contact with incompatible chemicals.
Acute Toxicity: Moderately toxic by oral and dermal exposure; estimated LD50 (oral, rat) between 200-2000 mg/kg; can cause nausea, vomiting, diarrhea if ingested in significant quantities.
Skin Corrosion/Irritation: Causes skin irritation, redness, possible blistering with prolonged contact.
Serious Eye Damage/Irritation: Causes severe eye irritation; corneal injury possible if not flushed promptly.
Respiratory Effects: Inhalation of dust may cause respiratory tract discomfort, coughing, shortness of breath.
Sensitization: May cause skin sensitization in sensitive individuals.
Chronic Effects: Repeated or prolonged exposure may produce cumulative health effects to skin, eyes, or respiratory tract.
Mutagenicity, Carcinogenicity, Reproductive Toxicity: Not classified as carcinogenic or mutagenic, limited data, handle with caution to avoid unnecessary exposure.
Ecotoxicity: Harmful to aquatic life; acute toxicity to fish and daphnia at concentrations above 10 mg/L, not readily biodegradable in standard OECD tests.
Persistence and Degradability: Phenolic structure may persist in natural waters and soils; slow biodegradation expected.
Bioaccumulation: Moderate potential due to log Kow; may accumulate in aquatic organisms.
Mobility in Soil: Moderately mobile, may reach groundwater with high rainfall or spills, but has some soil binding due to aromatic structure.
Other Adverse Effects: Avoid release to the environment, use appropriate waste containment at all steps.
Waste Treatment Methods: Dispose of as hazardous chemical waste by incineration or authorized chemical disposal contractor, avoid direct release to drains or watercourses.
Contaminated Packaging: Rinse containers with compatible solvents, discard in accordance with regional, national, and local regulations.
Special Precautions: Clearly label waste containers, store waste in leak-proof, sealed drums for safe transport.
UN Number: Not regulated under most transport regulations in small quantities, may be classified as a hazardous material in bulk.
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains 4-Bromocatechol).
Transport Hazard Class: 9 (Miscellaneous hazardous material, if applicable).
Packing Group: III (lower danger, if regulated).
Marine Pollutant: Yes, avoid transport with foodstuffs and animal feed.
Special Precautions: Transport with suitable labeling and documentation, comply with local transport authorities.
Labelling: Requires hazard pictograms and risk phrases on packaging in accordance with GHS/CLP guidelines.
Inventories: Listed in relevant chemical inventories including TSCA (USA), EINECS (Europe), DSL (Canada), ensure compliance before import/export.
REACH Compliance: Not subject to full REACH registration if imported/manufactured in small research quantities, verify with supplier.
Workplace Standards: Subject to hazard communication standards, proper training required before handling.
Special Regulations: Local and national guidelines may apply regarding use, release, and disposal to protect human health and the environment.
