Product Name: 4-Amino-M-Cresol
Chemical Formula: C7H9NO
Synonyms: 3-Methyl-4-aminophenol
CAS Number: 2835-99-6
Recommended Use: Intermediate in dye and chemical manufacturing
Supplier: Renowned chemical suppliers and manufacturers
Contact Information: Emergency phone numbers provided by distributing company, listed on package label
Restrictions: For laboratory, industrial, and research use only; not for food or drug use
Classification: Acute toxicity (oral, dermal); skin and eye irritation; possible environmental hazard
Label Elements: Hazard pictograms required on label, signal word “Warning”, hazard statements for acute toxicity and potential irritation
Potential Health Effects: Inhalation can irritate mucous membranes and upper respiratory tract; contact with skin and eyes may cause redness, pain, or burns; ingestion leads to gastrointestinal distress, dizziness, and possible CNS effects
Chronic Effects: Repeated exposure may impact liver or kidney function; sensitization risk for some users
OSHA Status: Classified as hazardous by OSHA Hazard Communication Standard
GHS Information: GHS/CLP labels specify irritant and toxicity features; advice to keep out of children’s reach
Chemical Name: 4-Amino-M-Cresol
Concentration: 98-100% pure substance for lab and manufacturing uses
Impurities: Trace organic and inorganic by-products from synthesis; variable by supplier
Identifiers: CAS 2835-99-6; EC Number 220-624-9
Inhalation: Move person to fresh air without delay; seek medical attention for coughing, dizziness, or breathing difficulties; provide artificial respiration if breathing has stopped
Skin Contact: Remove contaminated clothing, wash skin with soap and water for at least 15 minutes; contact physician if irritation persists or symptoms develop
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, lifting eyelids frequently; seek immediate medical evaluation
Ingestion: Do not induce vomiting; rinse mouth with water and give water to drink if person can swallow; arrange rapid medical attention
Special Medical Treatments: Provide safety data for health professionals; monitor for delayed symptoms; symptomatic care as advised by poison control
Suitable Extinguishing Media: Use dry chemicals, foam, carbon dioxide, or water spray; avoid using high-pressure water jets
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides, carbon monoxide, and carbon dioxide
Protective Equipment for Firefighters: Full-face self-contained breathing apparatus with chemical-resistant gloves and suit
Firefighting Instructions: Approach from upwind, isolate area, cool containers with water spray, stay clear of combustion zone
Personal Precautions: Ventilate area immediately; keep unprotected personnel away; use proper protective gear including gloves, goggles, and masks
Environmental Precautions: Prevent entry into drains, waterways, or soil; contain spill using dikes or absorbent materials
Cleanup Procedures: Use inert absorbent such as sand or vermiculite, scoop up carefully to avoid dust, place into labeled disposal containers; wash spill site after initial clean-up
Reporting: Notify authorities as required for spills above reportable quantities
Handling: Work in well-ventilated facilities; avoid generation of dust and inhalation; wear appropriate skin and eye protection; do not eat, drink, or smoke in handling areas
Storage Conditions: Store in tightly-closed containers away from moisture, sunlight, and incompatible agents; recommended temperature below 25°C in cool, dry areas; segregation from strong oxidizers, acids, bases recommended
Technical Precautions: Use fume hoods for laboratory manipulations, provide spill containment for bulk storage
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV; minimize exposure using industrial hygiene practices
Engineering Controls: Laboratory fume hoods, local exhaust ventilation, and HEPA filtration where necessary
Personal Protective Equipment: Nitrile or neoprene gloves, chemical goggles, face shields for splash risk, laboratory coats or coveralls; respiratory protection such as NIOSH-approved masks if airborne concentration expected
Hygiene Measures: Wash hands after use, remove contaminated clothing and clean before reuse
Appearance: Off-white to pale yellow crystalline powder
Odor: Slight phenolic odor
Melting Point: 125-128°C
Boiling Point: Data varies, expected above 250°C
Flash Point: Not easily flammable; test with care under strict conditions
Solubility: Moderately soluble in water, soluble in ethanol and organic solvents
pH: Typically neutral to slightly alkaline in water solution
Other Properties: Stable under general conditions, reacts with strong acids and oxidizers, decomposes before boiling
Chemical Stability: Timeline of stability extended under recommended storage conditions
Reactive Hazard: Reacts with acid chlorides, anhydrides, strong oxidizers, bases
Conditions to Avoid: Heat, moisture, storage near incompatible chemicals
Hazardous Decomposition: Breakdown forms toxic gases including ammonia, nitrogen oxides, carbon monoxide
Polymerization: No risk of hazardous polymerization observed
Routes of Exposure: Ingestion, inhalation, dermal, ocular
Acute Toxicity: Oral LD50 in rats approximately 375 mg/kg, demonstrating moderate toxicity; skin and eye irritation documented in animal studies
Chronic Exposure: Risk of kidney and liver effects with repeated or prolonged exposure; limited human epidemiological data
Symptoms: Irritation, redness, headache, nausea, abdominal pain, CNS depression at high doses
Sensitization: Documented risk in susceptible individuals, monitor for skin allergies
Ecotoxicity: Harmful to aquatic life at moderate to high concentrations; potential for toxicity in fish and invertebrate studies
Degradability: Data indicate moderate persistence in soil and water; partial breakdown by natural microbial activity
Bioaccumulation: Limited evidence for high bioaccumulation; monitoring required in industrial discharge regions
Mobility: Moderate mobility in aquatic systems; risk of contamination if released to water or soil
Aquatic Precaution: Control discharge to prevent harm to surface waters
Waste Treatment Methods: Incinerate under controlled chemical waste protocols; avoid landfill disposal where prohibited; use licensed hazardous waste processors
Packaging Disposal: Decontaminate and recycle or dispose as hazardous waste
Special Instructions: Reference federal, state, and local environmental agencies for compliance
UN Number: 2811
Shipping Name: Toxic solid, organic, n.o.s. (contains 4-Amino-M-Cresol)
Transport Hazard Class: Class 6.1 (toxic)
US Regulations: US EPA and OSHA list as regulated toxic substance; SARA Title III and RCRA requirements may apply
International Inventory: Listed on major chemical inventories such as TSCA, EINECS, DSL/NDSL
Hazard Ratings: NFPA and HMIS ratings assigned for health, fire, and reactivity based on supplier data
Other Compliance: Follow REACH registration and reporting in Europe; consult local and national regulatory agencies for up-to-date hazard communication rules
Worker Training: Ensure users understand chemical handling, emergency protocols, and legal responsibilities for safety
