Product Name: 3-Methoxyphenol
Synonyms: m-Methoxyphenol, Resorcinol monomethyl ether, 3-Hydroxyanisole
Chemical Formula: C7H8O2
Molecular Weight: 124.14 g/mol
CAS Number: 150-19-6
Recommended Use: Organic synthesis, chemical research, pharmaceutical intermediate
Supplier Details: Manufacturer and distributor contact information (phone, email, address) provided on product packaging and standard MSDS sheets
Emergency Contact: Chemtrec international or local emergency numbers supplied for fast reference in case of accident
Classification: Acute toxicity, skin and eye irritation, specific target organ toxicity
Labeling: GHS compliant labels, pictograms for irritant, exclamation mark
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing dust, vapors, or mists; use protective equipment; wash exposed skin thoroughly after handling
Signal Word: Warning
Physical Hazards: Not highly flammable but can combust at elevated temperature
Health Hazards: Exposure by inhalation, ingestion, or skin contact can lead to irritation or more severe health concerns at high doses
Environmental Hazards: Potentially hazardous to aquatic life with long-lasting impacts
Chemical Name: 3-Methoxyphenol
PURITY: Typically above 99% by weight
Common Impurities: Traces of anisole, phenol, and other methoxyphenol isomers (usually less than 1%)
Other Constituents: No additional hazardous ingredients expected or present based on manufacture’s declarations
Inhalation: Move person into fresh air, keep comfortable, consult a doctor if symptoms persist (dizziness, shortness of breath, or irritation)
Skin Contact: Remove contaminated clothing and rinse skin thoroughly with soap and water—seek medical advice if irritation shows or persists
Eye Contact: Flush open eyes gently with plenty of water for at least 15 minutes; remove contact lenses if present and easy to do so; get medical attention
Ingestion: Rinse mouth, never give anything by mouth if unconscious; do not induce vomiting—immediate medical attention recommended
Symptoms: Redness, headache, nausea, chemical burns possible following exposure
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide; avoid direct water jet on burning chemical
Special Hazards: Combustion releases irritating and toxic fumes—carbon monoxide, carbon dioxide, and phenolic compounds
Firefighting Procedures: Wear full protective gear including self-contained breathing apparatus; cool exposed containers with water spray to prevent pressure build-up
Explosion Data: Does not form explosive mixtures at standard use concentrations under normal conditions
Precautions: Remove all unnecessary personnel; prevent run-off to waterways
Personal Protection: Use gloves, splash goggles, face shield, and suitable protective clothing
Environmental Precautions: Contain spill to prevent entry into water, soil, or sewers—notify authorities in case of large spills or environmental contamination
Methods for Cleanup: Absorb liquid in inert material (sand, vermiculite), shovel into appropriate container for disposal, ventilate spill area
Decontamination: Wash area of spill thoroughly with water and mild detergent—dispose of contaminated material according to local and national regulations
Handling: Operate in well-ventilated areas; avoid breathing vapors, dust, or mists; minimize skin and eye contact; maintain good industrial hygiene by washing hands after use
Storage: Store in original, tightly closed containers in a cool, dry, well-ventilated location, away from sparks, open flames, or incompatible chemicals like oxidizers
Incompatibilities: Strong acids, strong bases, oxidizers, halogens
Storage Temperature: Keep containers tightly sealed between 2°C and 8°C if long term
Special Requirements: Label containers clearly, do not store near food, animal feed, or drinking water
Occupational Exposure Limits: No established OSHA/ACGIH TLVs, but control as for nuisance dust and phenolic materials—workplace exposure should not exceed recommended values for similar compounds
Engineering Controls: Fume hood, local exhaust, and general dilution ventilation
Personal Protective Equipment: Chemical resistant gloves (nitrile, neoprene), lab coat, safety goggles, face shield if splash risk exists
Respiratory Protection: NIOSH-approved mask if ventilation does not maintain airborne concentrations below recommended limits
Other Controls: Eye wash station and safety shower in working area
Appearance: Colorless or pale yellow crystalline solid
Odor: Mild, phenolic
Odor Threshold: No reliable data reported
Melting Point: 47–50 °C
Boiling Point: 243–245 °C
Flash Point: 122 °C
Evaporation Rate: Not measured, non-volatile at room temperature
Flammability: Not highly flammable but combustible
Vapor Pressure: 0.05 mmHg at 25 °C
Vapor Density: 4.3 (air = 1)
Solubility: Moderately soluble in water (15 g/L at 20°C); soluble in alcohol, ether
Partition Coefficient (log Kow): 1.17
Auto-Ignition Temperature: 400 °C
Decomposition Temperature: Not specified
Viscosity: Not applicable (solid at room temperature)
Reactivity: Stable under recommended storage conditions
Chemical Stability: Stable under ordinary conditions of use and storage; decomposition may occur at elevated temperatures, generating toxic vapors
Possible Hazardous Reactions: May react violently with strong oxidizing agents, acids, or bases
Conditions to Avoid: Excess heat, sunlight, sources of ignition, incompatible materials
Incompatible Materials: Strong oxidizers, strong acids and bases, halogens
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, phenol vapors
Routes of Exposure: Inhalation, ingestion, dermal, ocular
Acute Toxicity: LD50 (oral, rat): 810 mg/kg; irritation possible at lower doses
Chronic Effects: Long-term exposure may lead to dermatitis, liver or kidney effects, or sensitization
Symptoms: Skin redness, eye irritation, headache, nausea, mucous membrane irritation, central nervous system depression possible at high levels
Carcinogenicity: Not listed by IARC, NTP, OSHA as carcinogen
Mutagenicity: No mutagenic effects reported in standard assays
Reproductive Toxicity: Data not available; avoid unnecessary exposure
Aquatic Toxicity: Harmful to aquatic organisms based on structurally related substances; EC50 (daphnia magna): estimated to be 10–100 mg/L over 48 hours
Persistence and Degradability: Moderately biodegradable with potential for persistence in the environment if released in significant quantity
Bioaccumulation: Not expected to bioaccumulate significantly with a modest log Kow
Mobility in Soil: Potential to leach into groundwater; moderate mobility
Other Adverse Effects: Spillage or improper disposal can disrupt local ecosystems; prevent material from entering drains or water sources
Waste Treatment Methods: Dispose via properly licensed chemical waste facility
Incineration: Preferred disposal using approved incineration with flue gas scrubbing
Container Disposal: Triple rinse empty containers, puncture, and dispose as hazardous chemical waste if not reused
Legal Requirements: Always follow local, regional, and national waste disposal regulations for hazardous chemicals
Special Instructions: Do not discharge into sewers, on ground, or into water bodies
UN Number: Not classified as dangerous under most current international transport regulations
Proper Shipping Name: 3-Methoxyphenol
Transport Hazard Class: Not regulated as hazardous material by US DOT, IATA, IMDG
Packing Group: Not assigned
Environmental Hazards: Avoid release into environment during transit
Special Precautions: Package securely, label container plainly, include spill response instructions
Inventory Status: Listed on TSCA (US), EINECS (EU), DSL (Canada), and other national inventories
SARA Title III: Not considered a CERCLA hazardous substance or SARA extremely hazardous substance at normal laboratory volumes
California Proposition 65: Not listed
European Regulation: Classified according to EC No. 1272/2008 (CLP/GHS); requires standard pictogram and warning label
Workplace Regulations: U.S. OSHA standard for hazardous chemicals applies; ensure availability of Safety Data Sheets at workplace
Labeling Requirements: Clearly labeled with hazard pictograms, signal word, precautionary and hazard statements
