Product Name: 2-Bromo-p-cresol
Chemical Family: Brominated phenol derivatives
Synonyms: 2-Bromo-4-methylphenol
CAS Number: 95-65-8
Formula: C7H7BrO
Molecular Weight: 187.04 g/mol
Usage: Laboratory reagent, chemical synthesis, research chemistry
Manufacturer Contact: Manufacturer’s name, address, and emergency phone provided on product packaging or available through central safety administration.
GHS Classification: Acute toxicity (oral, dermal, inhalation); Skin and eye irritation; Environmental hazard (aquatic toxicity)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, toxic to aquatic life with long lasting effects
Precautionary Statements: Avoid breathing dust or vapor, wash skin thoroughly after handling, keep out of reach of untrained users, avoid release into the environment
Label Elements: Exclamation mark for irritation, dead fish/tree pictogram for environmental hazard
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Chemical Name: 2-Bromo-p-cresol
CAS Number: 95-65-8
Concentration: 98–100% as primary ingredient
Impurities: Trace by-products from synthesis, often phenol-based, concentration below regulatory reporting thresholds
Additives: None deliberate, pure grade intended for research and manufacturing use
Inhalation: Move person to fresh air, seek medical attention for persistent coughing, shortness of breath, or dizziness
Skin Contact: Remove contaminated clothing, wash skin with soap and plenty of water for at least 15 minutes, medical evaluation if irritation continues
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, continue rinsing, prompt medical evaluation for any sign of damage
Ingestion: Rinse mouth, avoid inducing vomiting, immediate medical attention recommended due to toxic potential
Acute Effects: Headache, nausea, skin redness, respiratory discomfort, eye watering and stinging
Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray for larger fires only
Unsuitable Media: Direct jet of water can spread burning material
Specific Hazards: Releases hydrogen bromide, carbon monoxide, and carbon dioxide when burned; smoke can be irritant and toxic
Protective Equipment: Full self-contained breathing apparatus, protective gear resistant to chemical splashes
Advice for Firefighters: Approach from upwind, contain run-off, avoid inhaling combustion products
Personal Protection: Chemical goggles, gloves, lab coat or chemical suit, use of local exhaust ventilation
Environmental Precautions: Prevent spills from reaching drains, sewers, or surface water, contain and collect spillage
Cleanup Procedures: Sweep up or vacuum material (using HEPA filter if dusty), transfer to sealable waste container, wash spill area with water and detergent, ventilate affected space
Disposal: Deliver waste and contaminated cleanup materials to licensed chemical disposal facility
Handling: Avoid contact with skin and eyes, prevent formation of dust and vapors, work in a fume hood or well-ventilated area, use tools dedicated to this chemical only
Technical Measures: Employ secondary containment, chemical-resistant, closed systems where possible
Storage Conditions: Store in tightly sealed container, cool, dry, and well-ventilated place, away from direct sunlight, incompatible chemicals (strong oxidizers, acids)
Incompatibilities: Oxidizing agents, strong acids, bases, sources of ignition
Engineering Controls: Local exhaust ventilation, laboratory fume hood, closed process systems for bulk amounts
Exposure Limits: No OSHA PEL, ACGIH TLV, or local workplace exposure limits specified; use caution for all dusts and vapors
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles or face shield, long-sleeved lab coat, closed-toe shoes, respiratory protection if airborne dust is generated
Hygiene Measures: Wash hands before eating or drinking, remove contaminated clothing, shower at end of work shift, keep work area clean
Form: White to off-white crystalline powder
Odor: Phenolic, slightly medicinal
Boiling Point: 243°C
Melting Point: 101–104°C
Solubility: Moderately soluble in organic solvents (ethanol, ether), slightly soluble in water
Density: 1.63 g/cm³
Vapor Pressure: Very low at room temperature
pH: Not applicable in solid form
Flash Point: Not readily flammable, but handle as combustible solid; flash point unavailable or above typical ambient temperatures
Chemical Stability: Stable under recommended storage and use conditions
Reactive With: Strong oxidizers, acid chlorides, alkali metals
Hazardous Reactions: Excess heat or moisture contact can degrade product, forming irritant and potentially toxic by-products
Decomposition Products: Hydrogen bromide, phenolic derivatives, carbon oxides
Polymerization: Not anticipated under normal conditions
Acute Toxicity: LD50 (oral, rat): estimated around 500–1,000 mg/kg, can cause moderate toxicity; data based on structurally related compounds
Inhalation Risk: Irritation to respiratory tract, headaches, possible dizziness at high concentrations
Skin Contact: Causes irritation, redness, possible allergic skin reactions in sensitized individuals
Eye Contact: Irritating, may cause pain, redness, tearing
Chronic Effects: Extended contact may lead to dermatitis, repeated exposure can affect liver or kidneys (based on phenolic analogues)
Carcinogenicity: Not listed as carcinogen by IARC, NTP, or OSHA
Ecotoxicity: Harmful to aquatic organisms, long-lasting effects on aquatic environment; do not allow contamination of water sources
Persistence and Degradability: Degrades slowly in environment, can persist and bioaccumulate in sediments and organisms
Bioaccumulation: Moderate potential; measured by log Kow values of structurally related compounds
Mobility in Soil: Moderate, binds moderately to most soil types, risk of leaching if spilled near water
Other Adverse Effects: May alter microbial populations in soil and water systems
Waste Handling: Treat as hazardous waste, store in compatible, properly labeled containers for disposal
Disposal Method: Engage licensed chemical waste contractor, incineration at approved facility, avoid discharge to sewage or municipal landfill
Contaminated Packaging: Must be triple rinsed, disposed as hazardous waste or incinerated, avoid re-use of packaging for any other purpose
Special Precautions: Empty containers retain chemical residue and vapors; dispose promptly and safely
UN Number: UN2811 for toxic solid, organic, n.o.s. (if applicable)
Proper Shipping Name: Toxic solid, organic, n.o.s. (2-Bromo-p-cresol)
Hazard Class: 6.1 (Toxic substances)
Packing Group: III (low danger for transport)
Labeling Requirements: Toxic (skull and crossbones), environmental hazard (where required)
Special Transport Precautions: Minimize temperature extremes, prevent accidental contact with incompatible materials
TSCA: Listed on the United States Toxic Substances Control Act Inventory
REACH: Should be registered for handling or manufacture >1 ton/year in the European Union
SARA 313: Not subject to SARA Title III Section 313 reporting (check for regional updates)
California Prop 65: Not listed as a known carcinogen or reproductive toxicant as of latest update
Other Regulations: Observe all applicable international, national, and regional regulations for hazardous chemicals, including workplace safety, environmental releases, and transport requirements
