Product Name: 2-Amino-p-Cresol
Chemical Formula: C7H9NO
CAS Number: 95-84-1
Synonyms: 4-Amino-2-methylphenol, p-Cresamin, 2-Methyl-4-aminophenol
Recommended Use: Intermediate for chemical synthesis, dye and pigment precursor
Supplier Details: Supplier identification, address, contact numbers, and emergency phone information included on product packaging and SDS
Emergency Phone: Refer to local regulations or company specific contact
GHS Classification: Acute Toxicity (Oral, Dermal, Inhalation), Serious Eye Damage, Skin Sensitization
Hazard Statements: Harmful if swallowed, in contact with skin, or if inhaled. Causes serious eye irritation. May cause allergic skin reaction.
Pictograms: Exclamation mark, Health hazard, Environment (if data available)
Signal Word: Warning
Precautionary Statements: Avoid breathing dust, wash thoroughly after handling, use only outdoors or in a well-ventilated area, wear protective gloves, clothing, and eye/face protection, do not eat, drink, or smoke when using product.
Other Dangers: May trigger asthma-like symptoms or skin sensitization in susceptible people.
Chemical Name: 2-Amino-p-Cresol
Concentration: >99%
Impurities/Additives: Minimal impurities, generally less than 1%, not believed to contribute to hazard classification
Molecular Weight: 123.16 g/mol
Inhalation: Remove person to fresh air. Seek medical advice if symptoms persist. Give oxygen if difficult breathing develops.
Skin Contact: Remove contaminated clothing immediately. Rinse skin under running water for at least 15 minutes. Seek medical help for persistent irritation or allergic reaction.
Eye Contact: Rinse continuously with water for several minutes, lifting eyelids. Remove contact lenses if present and easy to do. Call physician if irritation or vision changes occur.
Ingestion: Rinse mouth. Do not induce vomiting unless advised by medical personnel. Never give anything by mouth to someone unconscious. Get medical attention promptly.
Acute Symptoms: Burning sensation, cough, headache, nausea, skin or respiratory tract irritation.
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Unsuitable Extinguishing Media: Direct water jets may scatter chemical.
Specific Hazards: Emits toxic fumes of nitrogen oxides, carbon oxides, and phenolic compounds when burned.
Protective Equipment: Firefighters use self-contained breathing apparatus and chemical-resistant clothing.
Special Precautions: Move container from fire area if safe. Use water to cool fire-exposed containers. Contain runoff to prevent environmental contamination.
Personal Precautions: Evacuate unnecessary personnel. Wear suitable personal protective equipment, including chemical-resistant gloves, splash goggles, and respiratory protection.
Environmental Precautions: Prevent entry into drains, surface water, or soil.
Spill Cleanup Methods: Gather spillage mechanically. Avoid dust formation. Sweep or scoop material into suitable containers for disposal. Wash spill site after cleanup.
Other Notes: Notify regulatory authorities if material contaminates water or environment as per local laws.
Handling: Avoid contact with skin and eyes. Ensure adequate ventilation. Do not breathe dust. Wear proper personal protective equipment. Use explosion-proof equipment if dust clouds can form.
Safe Practices: Avoid eating, drinking, or smoking while working with this substance. Wash hands after use. Use appropriate waste containers.
Storage: Store in tightly closed original container, in a cool, dry, and well-ventilated place. Store away from incompatible substances like strong oxidizers or acids. Keep away from food, drinks, and animal feed.
Packaging Materials: Use chemically-resistant containers. Label containers clearly.
Exposure Limits: No OSHA or ACGIH exposure limits assigned; minimize exposure as no level is considered safe for all users.
Engineering Controls: Use local exhaust ventilation, fume hood, or general area ventilation to minimize airborne concentrations.
Personal Protection: Wear chemically-resistant gloves (nitrile or neoprene), lab coat or protective clothing, safety glasses with side shields, face shield for bulk handling. Respirators (NIOSH-approved) required where airborne concentrations may exceed safe levels.
Hygiene Practices: Keep work clothes separate; launder frequently. Wash hands before breaks and after handling.
Appearance: Pale yellowish to brownish crystalline solid
Odor: Slightly phenolic
Odor Threshold: Not established
pH: Weakly alkaline in aqueous solution
Melting Point: 121-123°C
Boiling Point: 273°C (estimated)
Solubility: Soluble in hot water; slightly soluble in cold water and organic solvents
Density: 1.16 g/cm³
Vapor Pressure: Low at room temperature
Flash Point: Not easily ignited, >150°C
Partition Coefficient (n-octanol/water): Log Kow 0.68 (estimated)
Other Properties: Stable under recommended storage; decomposes above melting point releasing toxic vapors.
Chemical Stability: Stable under recommended conditions and temperatures.
Incompatibilities: Strong oxidizers, acids, acyl chlorides, anhydrides.
Conditions to Avoid: Avoid contact with incompatible materials, excessive heat, moisture.
Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides, and phenolic compounds.
Hazardous Reactions: None expected under normal conditions.
Routes of Exposure: Inhalation, ingestion, skin/eye contact.
Acute Toxicity: Harmful by oral and dermal exposure; estimated oral LD50 (rat): 930 mg/kg
Skin Corrosion/Irritation: Can cause skin irritation and allergic response.
Eye Damage/Irritation: Causes serious eye irritation.
Respiratory Sensitization: Dust or vapor exposure can sensitize airways in susceptible people.
Chronic Toxicity: Prolonged skin exposure can cause dermatitis.
Carcinogenicity: Not classified as a known carcinogen by IARC, NTP, or OSHA.
Other Effects: Contact can cause headache, dizziness, nausea if inhaled or absorbed through skin.
Ecotoxicity: Harmful to aquatic organisms. Long-term adverse effects possible in aquatic environments.
Persistence and Degradability: Not readily biodegradable.
Bioaccumulative Potential: Low potential, log Kow suggests minimal buildup in organisms.
Mobility in Soil: Can leach to groundwater in large spills.
Other Adverse Effects: No detailed bioaccumulation or toxicity data available for most species.
Methods of Disposal: Dispose as hazardous waste by authorized facility in accordance with federal, state, and local regulations.
Product Disposal: Do not release to sewers, surface water, soil, or public waterways.
Packaging Disposal: Rinse containers, render them unusable, dispose according to local environmental regulations.
Additional Information: Incineration in approved facility preferred for larger volumes.
UN Number: Not regulated for transport under most international guidelines (consult local transport regulations if required)
UN Proper Shipping Name: Not allocated
Transport Hazard Class: Not classified
Packing Group: Not assigned
Environmental Hazards: Not classified as a marine pollutant
Special Precautions: Ensure containers remain tightly closed and minimize dust generation during transport
TSCA Status: Listed in the U.S. Toxic Substances Control Act Inventory
REACH Status: Registered or pre-registered in European Chemical Agency inventory (check specifics)
SARA Title III: Not listed as extremely hazardous (Section 302), not specifically listed in Section 313
California Proposition 65: Not listed
Other Regulatory Lists: OSHA Hazard Communication Standard applies; WHMIS (Canada): D2B (Toxic material causing other toxic effects)
Labeling Requirements: Comply with hazard, precautionary, and risk statements as stated above for workplace safety
