Product Name: 2,6-Dimethyl-4-Nitrophenol
Chemical Formula: C8H9NO3
Synonyms: 2,6-Xylenol, 4-nitro derivative; 4-Nitro-2,6-dimethylphenol
CAS Number: 609-95-4
Recommended Use: Research, synthesis in chemical laboratories, analytical reference
Supplier: Established scientific chemical distributor or laboratory supply entity; ensure direct sourcing for safety traceability
Contact Information: Accessible emergency phone, up-to-date digital communications, safety officer details
Classification: Eye irritant, skin irritant, hazardous to aquatic life, possible harmful effects if inhaled or ingested
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation; toxic to aquatic organisms; may trigger respiratory discomfort; may cause allergic skin reaction
Pictograms: Exclamation mark, environment, health hazard
Precautionary Statements: Use gloves, wear proper eye/face protection, avoid inhalation of dust, prevent release to environment, wash exposed areas thoroughly after handling
Chemical Identity: 2,6-Dimethyl-4-Nitrophenol
CAS Number: 609-95-4
Purity: 97% minimum (technical grade typical)
Impurities: Minor traces of unreacted xylenol, less than 1% residual solvents from synthesis
Molecular Weight: 167.17
Other Components: No additional hazardous additives reported
Eye Contact: Rinse immediately with lots of water for at least 15 minutes, remove contact lenses, continue rinsing, seek medical attention for irritation
Skin Contact: Wash skin thorough with soap and water, remove contaminated clothing, medical treatment necessary for continuing irritation or burns
Inhalation: Move person to fresh air, monitor for cough or breathing difficulty, seek medical care if symptoms persist
Ingestion: Rinse mouth with clean water, do not induce vomiting, immediate medical evaluation important
Notes for Physician: Treat symptomatically based on clinical judgment and patient response
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam; avoid water jets as spreading or reactivity may increase
Specific Hazards: Decomposition releases toxic gases, including nitrogen oxides and carbon oxides; risk of intense local heat
Protective Equipment: Full protective gear for firefighters, including self-contained breathing apparatus
Measures: Stay upwind, prevent run-off from entering watercourses, cool containers with water spray far from fire site
Personal Precautions: Wear gloves, lab coat, goggles, suitable respirator in case of dust, avoid contact with eyes and skin
Environmental Precautions: Block entry to drains, rivers, and soil; isolate spill area
Cleaning Up: Scoop up solid with inert absorbent, transfer to sealed hazardous waste container, ventilate affected zone, decontaminate surfaces with suitable detergent, avoid raising dust
Disposal: Observe local and national regulations for hazardous waste, detailed instructions below
Handling: Operate in fume hood or well-ventilated lab, use only with proper PPE, minimize dust generation, do not eat, drink, or smoke in work area
Storage: Store locked in tightly closed containers, away from strong oxidizers or sources of ignition, maintain in cool, dry conditions, clearly labeled chemical storage for hazardous organics
Other Considerations: Keep away from incompatible materials like strong bases and acids, segregate from food and feedstuffs
Exposure Limits: No established OSHA/ACGIH limits for this compound; avoid occupational exposure, follow best laboratory practice
Engineering Controls: Local exhaust ventilation, chemical fume hood, eyewash station and safety shower must be nearby
Personal Protection: Chemical splash goggles, gloves resistant to organic chemicals (nitrile), lab coat, P2 or N95 particulate respirator if airborne dust expected
Hygiene Measures: Wash hands and face after handling, do not share lab clothing, regular training and standardized PPE audits improve compliance
Appearance: Yellow to orange crystalline solid
Odor: Slight phenolic, not sharply pungent
pH: Not applicable for solid, acidic in solution
Melting Point: 116-120 °C
Boiling Point: Decomposes before boiling
Flash Point: Data not clearly established, handle as potentially combustible
Vapor Pressure: Extremely low at ambient temperature
Solubility: Low in water, moderate in organic solvents like ethanol, acetone
Partition Coefficient (log Pow): Estimated 1.5-2.3
Density: 1.3-1.35 g/cm³
Stability: Stable under recommended storage, decomposes on strong heating
Chemical Stability: Stable in closed containers at cool, dry conditions, avoid heat and light
Reactivity: Mildly reactive with oxidizers or strong reducing agents
Hazardous Reactions: Risk of exothermic decomposition if overheated; nitrophenols prone to slow darkening over time
Incompatible Materials: Strong acids, alkalis, oxidizing agents, reducing agents, some metals
Decomposition Products: Nitrogen oxides, phenolic vapors, carbon monoxide, carbon dioxide
Acute Toxicity: Limited study data; acute oral toxicity estimated at moderate (LD50 rat oral approx. 350-600 mg/kg)
Routes of Exposure: Eyes, skin, inhalation of dust, ingestion
Symptoms: Eye/skin irritation, headache, cough, nausea with substantial exposure, sensitization may occur on repeated contact
Chronic Toxicity: Data limited; long-term effects from chronic exposure not fully characterized; similar compounds have reported liver and kidney effects
Carcinogenicity: Not classified by IARC, NTP, or OSHA
Mutagenicity / Reproductive Toxicity: Data insufficient for definitive statements; treat with caution due to nitrophenolic structure
Aquatic Toxicity: Harmful or toxic to aquatic organisms, low concentrations may impact algae and invertebrates
Persistence and Degradability: Moderate to low biodegradability, nitrophenols tend to resist easy breakdown
Bioaccumulative Potential: Moderate risk of bioaccumulation, especially in low-flow waterways
Mobility in Soil: Moderately mobile, may leach through sandy soil in high rainfall areas; weakly adsorbed to organic matter
Other Adverse Effects: Avoid release to waterways and soil, potential long-term percolation into groundwater
Waste Handling: Treat unused and contaminated material as hazardous waste; do not mix with general trash; never pour down drains
Methods: Incineration in licensed chemical waste facility; chemical destruction for small quantities after neutralization and specialist advice
Container Disposal: Triple rinse and puncture before disposing in hazardous waste stream; label as persistent organic chemical
Regulatory Compliance: Observe all local and national guidelines; obtain waste transfer documentation with hazardous waste codes
UN Number: 2811 (Toxic Solid, Organic, N.O.S.) as reference for similar organonitro phenols
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III (lowest relative danger within toxic substances)
Labels: Toxic, environmental hazard
Transport Precautions: Secure tightly closed containers, insulate from direct sunlight, avoid rough handling, emergency procedures for spills or personnel contact during transit
Regulations: Subject to national and international ADR/RID, IMDG, IATA rules
US TSCA: Listed or subject to reporting for manufacture/import
EU REACH: Pre-registration or notification may apply, check current status
OSHA: Treat as hazardous chemical under Hazard Communication Standard
Other National Inventories: Check country-specific lists, including Canadian DSL/NDSL, Australian AICS, Japanese ENCS
Label Requirements: Hazard pictograms, precautionary, hazard, and signal word statements; reference UN and GHS alignment
Worker Safety: Handle under written standard operating procedures, keep SDS accessible to exposed workers
