Chemical Name: 2,3,6-Trimethylphenol
Synonyms: 2,3,6-Trimethyl-1-hydroxybenzene; Mesitol
CAS Number: 2416-94-6
Recommended Use: Intermediate for organic synthesis, chemical research, fine chemicals manufacturing
Supplier: Information available from manufacturer, ensure to contact local supplier for precise detail
Emergency Phone: Based on local and regional regulations, refer to provided packaging for emergency contact numbers
GHS Classification: Eye Irritant (Category 2), Skin Irritant (Category 2), Acute Toxicity Oral (Category 4), Acute Toxicity Inhalation (Category 5)
Label Elements: Exclamation mark symbol, hazard statements regarding irritation and toxicity
Hazards: May cause moderate eye and skin irritation, harmful if swallowed or inhaled, may provoke respiratory irritation or discomfort
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Precautionary Statements: Avoid breathing dust, avoid contact with eyes and skin, use in well-ventilated place, wash hands thoroughly after handling
Substance Name: 2,3,6-Trimethylphenol
Chemical Formula: C9H12O
Concentration: >99% w/w (as supplied, analytical grade)
Impurities/Other Components: Trace methylphenols, possible trace solvents depending on production lot
Molecular Weight: 136.19 g/mol
Inhalation: Move person to fresh air, support breathing if symptoms develop, seek medical attention for persistent irritation or distress
Skin Contact: Remove contaminated clothing, wash area thoroughly with soap and water, monitor for irritation, seek medical attention if rash or discomfort persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get medical advice if irritation continues
Ingestion: Rinse mouth if conscious, do not induce vomiting, seek medical attention immediately
Suitable Extinguishing Media: Dry chemical powder, carbon dioxide, water spray, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water jet may not be effective
Specific Hazards: May emit toxic fumes of carbon monoxide, carbon dioxide, methylated phenols when burned
Protective Equipment: Firefighters should use self-contained breathing apparatus and full protective gear
Special Procedures: Use caution in confined spaces, cool exposed containers with water spray to prevent pressure build-up
Personal Precautions: Wear protective gloves, goggles, and suitable clothing, ensure adequate ventilation, avoid dust formation
Environmental Precautions: Prevent entry to drains or water systems, contain spill using inert absorbent material
Cleanup Methods: Scoop up material and place in a labeled waste container, wash area with water and mild detergent, dispose of contaminated materials as chemical waste
Handling: Operate in a well-ventilated environment, avoid inhalation or prolonged skin contact, use appropriate PPE, keep containers tightly closed after use
Storage: Store in a cool, dry place away from heat and direct sunlight, keep away from incompatible substances such as strong oxidizers and acids, lock storage area if possible, secure containers upright and clearly labeled
Occupational Exposure Limits: No established exposure limits per OSHA or ACGIH for this compound, limit exposure by engineering controls
Engineering Controls: Use fume hoods or local exhaust in laboratory settings, maintain good general ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety goggles or face shield, lab coat, splash-resistant footwear
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink near product use, remove contaminated clothing before entering shared areas
Appearance: Pale yellow to white crystalline solid
Odor: Mild aromatic
Melting Point: 62–65°C
Boiling Point: 232–234°C
Flash Point: 114°C (closed cup)
Solubility: Slightly soluble in water, readily soluble in organic solvents such as ethanol and ether
Vapor Pressure: Low at room temperature
Density: 1.04–1.07 g/cm³ at 20°C
pH: Not applicable (solid state)
Partition Coefficient (log Kow): Data indicates moderate hydrophobic character
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: No hazardous reactivity expected under normal conditions
Incompatible Materials: Strong oxidizing agents, strong acids, peroxides
Hazardous Decomposition: Heating or combustion generates toxic gases including carbon oxides and methylated phenols
Polymerization: Will not polymerize spontaneously
Acute Toxicity: Oral (rat): LD50 ranges from 200 to 500 mg/kg
Chronic Toxicity: No extensive long-term studies, repeated or prolonged exposure may irritate skin, eyes, or respiratory tract
Symptoms: Irritation of skin or eyes, headache, dizziness, respiratory discomfort, nausea if inhaled or ingested
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Other Effects: No specific evidence for reproductive or developmental toxicity
Ecotoxicity: Harmful to aquatic life if large quantities enter waterways
Persistence and Degradability: Expected to degrade slowly in environment, not readily biodegradable
Bioaccumulation Potential: Moderate due to hydrophobic nature, may build up in aquatic organisms
Mobility in Soil: Limited, but leaching possible in loose, sandy soils
Additional Notes: Avoid unauthorized release into environment, comply with local environmental policies
Disposal Methods: Send waste material to licensed hazardous chemical waste facility, follow local, regional, and national regulations
Product Disposal: Incinerate under controlled conditions if allowed, do not dispose in regular municipal waste
Packaging Disposal: Rinse empty containers, render unusable, dispose in accordance with environmental protection authority guidance
UN Number: Not allocated for this material
Transport Hazard Class: Usually not regulated under standard transport classifications, check shipping documents for updates
Packing Group: Not assigned
Environmental Hazards: Not designated as marine pollutant, but best practices recommend secondary containment for large shipments
Special Precautions: Secure containers, avoid direct sunlight and moisture during transit
TSCA Status: Listed on United States Toxic Substances Control Act Inventory
REACH Registration: Registered or exempted in the European Union chemicals database
Other International Inventories: Included in Canada DSL, Australia AICS, Japan ENCS, Korea ECL
Hazard Statements: Comply with workplace labeling and safety sheet regulations
Additional Legislation: Follow all applicable health, safety, transport, and environmental rules for chemical substances
