Product Name: 1,4-Naphthoquinone
Chemical Formula: C10H6O2
Synonyms: Para-naphthoquinone, Quinone, 1,4-Naphthoquinone
CAS Number: 130-15-4
Manufacturer: List supplier or company contact details
Recommended Use: Laboratory chemicals, synthesis, reference material
Restrictions: Industrial/intermediate use, not for food, drug, or household application
Classification: Acute Toxicity—Oral: Category 3; Acute Toxicity—Inhalation: Category 3; Eye Irritant: Category 2A; Skin Irritant: Category 2
Signal Word: Danger
Hazard Statements: Toxic if swallowed; May cause allergy or asthma symptoms or breathing difficulties if inhaled; Causes serious eye irritation; Causes skin irritation
Pictograms: Skull and Crossbones, Exclamation Mark
Precautionary Statements: Avoid breathing dust or vapors; Wash hands thoroughly after handling; Wear protective gloves, clothing, and eye protection; Do not eat, drink, or smoke when using this product
Target Organs: Eyes, skin, respiratory system, central nervous system
Potential Health Effects: Rapid onset of headache, confusion, irritation, shortness of breath, severe eye damage
Chemical Name: 1,4-Naphthoquinone
Common Name: Para-naphthoquinone
Concentration: Typically ≥ 98%
Impurities: Trace amounts of related naphthoquinones or residual solvents (depending on supplier)
EC Number: 204-977-6
Molecular Weight: 158.16 g/mol
Inhalation: Move to fresh air immediately, keep at rest, seek medical attention if symptoms persist or breathing becomes difficult
Skin Contact: Rinse thoroughly with water for at least 15 minutes, remove contaminated clothing, seek medical support if irritation or burns appear
Eye Contact: Flush eyes continuously with plenty of water for at least 20 minutes, hold eyelids apart, remove contact lenses if present, and immediately seek medical help
Ingestion: Do not induce vomiting, rinse mouth with water, get urgent medical advice and show the product safety data sheet
Symptoms and Effects: Cough, shortness of breath, skin redness, severe eye redness, dizziness, nausea, potential delayed symptoms
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, alcohol-resistant foam
Unsuitable Media: Do not use a high-powered water jet as it may spread the chemical
Hazards from Combustion: Toxic and irritating gases and vapors like carbon monoxide, carbon dioxide, and organic compounds may develop
Protective Equipment: Full protective clothing, self-contained breathing apparatus, face shield, and boots, avoid inhalation of smoke and combustion products
Special Firefighting Instructions: Evacuate area, contain water used for firefighting, do not allow runoff to contaminate water sources or drains
Personal Precautions: Restrict access to area, ventilate enclosed spaces, avoid dust generation, use appropriate respirator, rubber gloves, safety goggles, and disposable suits
Environmental Precautions: Prevent spillage from entering drains, sewers, and open waterways
Containment/Methods for Cleaning Up: Collect and sweep up spilled material using tools and shovels, avoid raising dust, transfer waste into well-labeled, tightly sealed containers, clean area with water and detergent after collection
Precautions for Safe Handling: Use in well-ventilated environments, wear protective equipment, reduce dust formation and direct contact, do not eat, drink, or smoke in work area, wash hands after handling
Storage Conditions: Keep container tightly sealed in a dry, cool, and well-ventilated location, segregate from oxidizers, reducers, acids, and incompatible chemicals, label storage with hazard indicators
Material Incompatibility: Strong oxidizing agents, alkaline substances, reducers, and strong bases may cause hazardous reactions
Occupational Exposure Limits: Consult your local regulations, no established OSHA or ACGIH limits, use lowest achievable exposure
Engineering Controls: Fume hood, exhaust ventilation, dust collection devices, process enclosures
Personal Protection: Face shield, goggles with side shields for splash hazards, nitrile or butyl rubber gloves, lab coat or disposable coveralls, safety boots, approved respirator if dust is generated or ventilation is inadequate
Hygiene Practices: Change contaminated clothing, clean protective gear before reuse, maintain eyewash stations and emergency showers nearby
Appearance: Yellow to orange crystalline solid
Odor: Characteristic strong quinone odor
Melting Point: 125–128 °C
Boiling Point: 295 °C (decomposes)
Flash Point: 150 °C
Solubility: Slightly soluble in cold water, more soluble in ethanol, ether, and chloroform
Vapor Pressure: Very low at 20 °C
Density: 1.41 g/cm³ at 20 °C
pH: Not applicable (insoluble in water)
Partition Coefficient (log Kow): Approx. 1.85
Auto-ignition Temperature: Not established
Decomposition Temperature: Above 250 °C
Stability: Stable under recommended storage conditions
Reactive Hazards: Exposed to air and light for long periods may degrade product
Conditions to Avoid: Moisture, heat, open flames, static discharge, strong sunlight
Incompatible Materials: Strong oxidants, alkalis, reducing agents, strong bases
Hazardous Decomposition: Decomposition can yield toxic fumes including carbon monoxide, carbon dioxide, and organic vapors
Acute Toxicity: LD50 (oral, rat): 190 mg/kg, LC50 (inhalation, rat): 0.27 mg/L/4h
Skin Corrosion/Irritation: Causes skin irritation, redness, blister formation
Serious Eye Damage/Irritation: High risk of severe eye injury and potential corneal damage
Respiratory Sensitization: Inhalation can lead to respiratory issues, coughing, asthma, or lung damage
Carcinogenicity: No studies suggesting direct carcinogenic effects, absence of long-term data
Reproductive Toxicity: Insufficient data to classify as reproductive toxin
Mutagenicity: Positive results in certain in-vitro tests
Symptoms from Exposure: Dizziness, nausea, coughing, severe skin and eye redness, delayed central nervous system effects
Aquatic Toxicity: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Biodegradation in environment expected to be slow
Bioaccumulation Potential: Moderate, log Kow suggests some bioaccumulation possible
Mobility in Soil: Binds to particulate matter, moderate mobility
Additional Notes: Avoid contamination of soil, surface water, and groundwater
Waste Treatment Methods: Treat as hazardous waste, contact licensed waste disposal contractors
Disposal of Product: Use EPA or local authorized facility that complies with chemical disposal regulations
Container Disposal: Decontaminate and dispose of empty containers as hazardous material or recycle where possible
Contaminated Packaging: Triple rinse with water and a compatible solvent, keep rinsate for hazardous waste disposal, do not reuse packaging
Additional Precautions: Do not discharge to sewer, waterways, or soil
UN Number: 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (1,4-Naphthoquinone)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Label: Toxic
Transport by Road/Rail (ADR/RID): Class 6.1, Packing Group III, environment hazard considerations
Transport by Air (ICAO/IATA): Class 6.1, Packing Group III
Transport by Sea (IMDG): Class 6.1, Packing Group III, avoid contamination of marine environments
Special Transport Precautions: Well-sealed, sturdy containers, temperature control not usually required, comply with local and international transport codes
US Federal Regulations: Listed in TSCA inventory, not subject to SARA Title III, Section 313
OSHA: Covered under Hazard Communication Standard (29 CFR 1910.1200)
EU Regulations: Classified according to Regulation (EC) No 1272/2008, must be labeled and handled under REACH guidelines, subject to hazard communication
Canada: Included in DSL/NDSL inventory
International Inventories: Listed in major chemical inventories (Australia, Japan, China, South Korea)—check local agreements
Other Rules: Responsibility falls on employer and worker training, labeling, and access to updated MSDS and hazard signage at point of use
