Product Name: 1,4-Benzoquinone
Synonyms: para-Benzoquinone, p-Benzoquinone, quinone, quinone-1,4
CAS Number: 106-51-4
EC Number: 203-405-2
Recommended Use: Laboratory reagent, dye intermediate, oxidizing agent
Manufacturer Name: Consult product label or supplier
Emergency Phone: Refer to local, state, or national guidelines
Hazard Class: Acute toxicity, skin corrosion/irritation, serious eye damage/irritation, respiratory sensitization
Label Elements: Danger, skull and crossbones pictogram, exclamation mark
Signal Word: Danger
Hazard Statements: Toxic if inhaled, swallowed, or absorbed through skin. Causes severe skin burns and eye damage. Harmful to aquatic life.
Precautionary Statements: Avoid contact with skin and eyes, do not breathe dust or vapors, use only outdoors or in a well-ventilated area, keep container tightly closed.
Chemical Name: 1,4-Benzoquinone
Purity: Greater than or equal to 99%
Common Impurities: Hydroquinone, phenol derivatives
Molecular Formula: C6H4O2
Molecular Weight: 108.09 g/mol
Inhalation: Move individual to fresh air immediately. Provide oxygen or artificial respiration if breathing is difficult. Seek medical attention without delay.
Skin Contact: Remove contaminated clothing and wash skin with plenty of water for at least 15 minutes. Immediate medical attention required.
Eye Contact: Rinse eyes thoroughly with water for at least 15 minutes, lifting eyelids occasionally. Obtain medical attention immediately.
Ingestion: Rinse mouth. Do not induce vomiting. Give water if victim is conscious. Get medical aid as soon as possible.
Most Important Symptoms: Severe irritation, burns, headache, dizziness, eye damage, difficulty breathing.
Advice for Physicians: Treat symptomatically and supportively. Monitor for delayed pulmonary edema.
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, foam. Avoid using a direct stream of water.
Unsuitable Media: High-pressure water jets may spread material.
Hazards from Combustion: Produces irritating, corrosive, and possibly toxic gases including carbon monoxide and carbon dioxide.
Protective Equipment: Full protective clothing and self-contained breathing apparatus for firefighters.
Special Procedures: Evacuate area if possible. Use water spray to cool containers exposed to fire.
Personal Precautions: Evacuate non-essential personnel, avoid breathing dust or vapor, wear protective gloves, eye protection, and fit-tested respirator if needed.
Environmental Precautions: Prevent further leakage or spillage if safe. Do not let material enter drains or environment.
Clean-up Methods: Scoop spilled substance into suitable containers. Absorb residue with inert material such as sand or vermiculite. Provide adequate ventilation. Dispose of according to local regulations.
Handling: Avoid skin and eye contact. Avoid inhalation of dust or vapor. Use in well-ventilated areas. Practice good hygiene, wash thoroughly after use.
Storage: Store in tightly closed containers in a cool, dry, well-ventilated area away from incompatible substances, heat, and sources of ignition. Keep away from strong acids, strong bases, reducing agents.
Incompatible Products: Strong acids, strong bases, reducing agents, combustible material.
Exposure Limits: OSHA PEL: 0.1 ppm TWA; ACGIH TLV: 0.1 ppm TWA
Engineering Controls: Ensure proper ventilation and local exhaust. Use fume hood in laboratory settings.
Personal Protective Equipment (PPE): Chemical-resistant gloves, safety goggles or face shield, lab coat, suitable respiratory protection if airborne exposure is possible.
Other Protection: Emergency eyewash stations and safety showers, wash hands and skin after handling, remove contaminated clothing before leaving work area.
Appearance: Yellow crystalline solid
Odor: Sharp, unpleasant and pungent
Odor Threshold: Low, easily detectable
pH: Not applicable (solid)
Melting Point: 115–116°C
Boiling Point: 108°C at 11 hPa
Flash Point: 79°C (closed cup)
Evaporation Rate: Data not available
Flammability: Flammable solid
Vapor Pressure: 1.5 mmHg at 25°C
Vapor Density: 3.72 (air = 1)
Solubility: Slightly soluble in water, readily soluble in ethanol, ether, and benzene
Partition Coefficient (log Kow): 0.2
Auto-ignition Temperature: 380°C
Decomposition Temperature: Data not available
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions. Sensitive to heat, light, and moisture.
Reactivity: Reacts with reducing agents, bases, strong acids. Incompatible with combustibles.
Hazardous Reactions: Vapors may form explosive mixtures with air.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, possible toxic fumes.
Conditions to Avoid: Heat, flames, sparks, moisture, direct sunlight.
Routes of Entry: Inhalation, skin contact, ingestion, eye contact
Acute Effects: Toxic by all routes, causes burns, may affect central nervous system, damages lungs, eyes, and skin
Chronic Effects: Repeated or prolonged exposure may cause affect liver, kidneys, or lead to sensitization
LD50 (oral, rat): 130 mg/kg
LC50 (inhalation, rat): 11 mg/m³ (4 hr)
Symptoms: Burning sensation, cough, wheezing, shortness of breath, red or blistered skin
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, EPA
Other Toxicity Data: Can induce methemoglobinemia at high doses
Toxicity to Aquatic Life: Harmful to aquatic organisms, may cause long-term adverse effects
Persistence and Degradability: Moderately persistent, can undergo photodegradation
Bioaccumulative Potential: Low, estimated bioconcentration factor (BCF) under 10
Mobility in Soil: Relatively mobile, but rapid degradation reduces environmental impact
Other Adverse Effects: No data on ozone depletion, global warming, or other indirect effects
Waste Treatment Methods: Burn in a chemical incinerator equipped with afterburner and scrubber. Neutralize carefully before disposal.
Contaminated Packaging: Dispose of as hazardous waste. Containers should be emptied and rinsed before recycling or disposal.
Regulations: Abide by all local, state, national, and international hazardous waste regulations. Incinerate where allowed.
UN Number: UN2587
Proper Shipping Name: 1,4-Benzoquinone
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Label Required: Toxic
Environmental Hazards: Harmful to aquatic environment
Special Precautions: Avoid rough handling, keep containers upright, inform carriers of dangers
OSHA: Listed as hazardous
TSCA: Listed on US Toxic Substances Control Act inventory
SARA Title III: Section 313: subject to reporting
REACH Regulation (EU): Registered substance, follows restrictions
DSL/NDSL (Canada): Listed or may be subject to notification
Other International Inventories: Listed in AICS (Australia), ENCS (Japan), KECL (Korea), PICCS (Philippines), NZIoC (New Zealand)
GHS Classification: Covers acute toxicity, skin and eye damage, aquatic hazard
