Product Name: 1,2-Benzoquinone
Synonyms: ortho-Benzoquinone, o-Quinone
Chemical Formula: C6H4O2
Molecular Weight: 108.09 g/mol
CAS Number: 526-51-4
Manufacturer: Refer to supplier’s physical label
Recommended Use: Laboratory reagent, organic synthesis intermediate
Emergency Contact: Refer to workplace emergency numbers
GHS Classification: Acute Toxicity (Oral, Category 3), Skin Corrosion/Irritation (Category 2), Eye Damage/Irritation (Category 2A), Specific Target Organ Toxicity (Single Exposure, Category 3), Aquatic Chronic Toxicity (Category 2)
Signal Word: Danger
Hazard Statements: Toxic if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation, toxic to aquatic life with long lasting effects
Precautionary Statements: Avoid breathing dust/fume/gas/mist/vapors/spray, wash thoroughly after handling, avoid release to the environment, use personal protective equipment as required
Pictograms: Skull and crossbones, exclamation mark, health hazard, aquatic hazard
Chemical Name: 1,2-Benzoquinone
Concentration: ≥98% by weight
Impurities: Trace phenols, hydroquinone may be present in low concentrations
CAS Registry Number: 526-51-4
EC Number: 208-392-1
Inhalation: Move exposed person to fresh air, keep person warm and at rest, seek medical attention for any breathing difficulty or if symptoms persist
Skin Contact: Remove contaminated clothing and shoes, immediately wash skin with plenty of soap and water, seek medical attention for irritation or allergic reaction
Eye Contact: Immediately rinse eyes with plenty of water for at least 15 minutes, ensure eyelids are held apart, seek medical attention without delay
Ingestion: Rinse mouth with water, never give anything by mouth to an unconscious person, seek medical attention immediately, do not induce vomiting unless directed by medical personnel
Most Important Symptoms/Effects: Burning sensation, coughing, wheezing, shortness of breath, skin and eye redness, possible allergic reactions
Suitable Extinguishing Media: Dry chemical, CO2, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Full water jet
Specific Hazards: Emits toxic fumes of carbon oxides under fire conditions, dust may form explosive mixtures with air
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and protective clothing
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, irritating fumes and smoke
Personal Precautions: Evacuate unnecessary personnel, ventilate area, wear respiratory protection and protective clothing including eye and face protection
Environmental Precautions: Prevent spillage from entering soil, sewers, and waterways
Methods for Cleanup: Absorb spillage in suitable inert material (sand, earth, diatomaceous earth), place in container for disposal using appropriate methods, clean contaminated surfaces with soap and water, ensure adequate ventilation, avoid generating dust, dispose as hazardous waste
Precautions for Safe Handling: Handle in well-ventilated area, avoid contact with skin, eyes, and clothing, avoid breathing dust, wash hands and face thoroughly after handling, use proper personal protective equipment
Storage Conditions: Store tightly closed in original container, keep in a cool, dry, well-ventilated location, segregate from incompatible materials such as strong bases, strong oxidizers, and reducing agents, keep away from heat and direct sunlight
Incompatibilities: Bases, reducing agents, strong oxidizing agents
Occupational Exposure Limits: No specific OSHA or ACGIH exposure limits established; minimize exposure as low as reasonably achievable
Engineering Controls: Use chemical fume hood, emergency shower and eyewash stations should be nearby, ensure proper ventilation
Personal Protection: Wear chemical-resistant gloves (nitrile or neoprene), safety goggles, lab coat or chemical-resistant apron, use NIOSH-certified respirator if exposure limits are exceeded or in case of inadequate ventilation
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling, avoid eating, drinking, or smoking in work area
Appearance: Yellow crystalline solid
Odor: Distinct, penetrating, unpleasant
Odor Threshold: Not established
Melting Point: 55–57 °C
Boiling Point: 108 °C at 14 mmHg
Vapor Pressure: Not available
Density: 1.31 g/cm3
Solubility: Moderately soluble in water; soluble in ethanol, ether, and chloroform
pH: Not applicable
Partition Coefficient (log Kow): 0.2
Flash Point: Not available
Autoignition Temperature: Not determined
Explosive Limits: Not determined
Decomposition Temperature: Not known
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts with strong bases, strong oxidizers, and strong reducing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, other irritating and toxic gases
Possibility of Hazardous Reactions: Dust may form explosive mixtures with air, may react violently with incompatible materials
Conditions to Avoid: Excess heat, open flame, incompatible materials, humidity, light
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (mouse): 89 mg/kg; data for humans limited
Skin Corrosion/Irritation: Causes skin irritation
Serious Eye Damage/Irritation: Causes serious eye irritation
Respiratory or Skin Sensitization: May cause allergic skin reaction
Carcinogenicity: No data, not listed by IARC, NTP, OSHA
Mutagenicity: Evidence of mutagenic activity from in vitro studies
Reproductive Toxicity: No data available
Specific Target Organ Toxicity (Single Exposure): May cause respiratory irritation
Chronic Effects: Prolonged exposure may cause dermatitis or respiratory effects
Toxicity to Aquatic Life: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Not readily biodegradable, may persist in the environment
Bioaccumulative Potential: Low, based on estimated log Kow
Mobility in Soil: Likely to have moderate mobility
Other Adverse Effects: Avoid release into environment, impacts on microorganisms and aquatic life occur at low concentrations
Waste Disposal Methods: Dispose of product and contaminated packaging as hazardous waste in accordance with local, regional, and national regulations, incineration or chemical treatment recommended where permitted
Contaminated Packaging: Rinse containers with appropriate solvent, dispose as hazardous waste
Special Precautions: Do not dispose of via sewage system, open dumping or uncontrolled landfilling must be avoided
UN Number: 2811
UN Proper Shipping Name: Toxic Solid, Organic, N.O.S. (1,2-Benzoquinone)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions for User: Avoid contact during handling and transport, follow proper emergency procedures in case of spillage
US TSCA: Listed
EU Regulation (REACH): Substance of very high concern (SVHC) registration may apply
Canada (DSL/NDSL): Listed
Australia (AICS): Listed
Labeling Requirements: Follow OSHA, GHS, and local regulatory guidelines, hazard labeling and safety data sheets required in workplace settings
Other Regulations: Workplace exposure controls required, hazardous communication training recommended for all personnel, hazardous waste generator rules apply
